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Prognostic PET [11C]-acetate uptake is associated with hypoxia gene expression in patients with late-stage hepatocellular carcinoma – a bench to bed study
BackgroundPositron Emission Tomography (PET) with combined [ 18 F]-FDG and [ 11 C]-acetate (dual-tracer) is used for the management of hepatocellular...
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A review of PET attenuation correction methods for PET-MR
Despite being thirteen years since the installation of the first PET-MR system, the scanners constitute a very small proportion of the total hybrid...
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Recent Update on PET/CT Radiotracers for Imaging Cerebral Glioma
Positron emission tomography/computed tomography (PET/CT) has dramatically altered the landscape of noninvasive glioma evaluation, offering...
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Use of 11C-acetate PET imaging in the evaluation of advanced atherogenic lesions
The use of 11 C-acetate as a PET/CT tracer for atherosclerotic lesions preferentially labels anti-inflammatory/pro-resolution intra-plaque...
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Uncovering atherosclerotic cardiovascular disease by PET imaging
Assessing atherosclerosis severity is essential for precise patient stratification. Specifically, there is a need to identify patients with residual...
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PET imaging of new target CDK19 in prostate cancer
PurposeProstate-specific membrane antigen (PSMA)-positron emission tomography (PET) is a superior method to predict patients’ risk of cancer...
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The Potential Role of PET in the Management of Peripheral Artery Disease
Purpose of ReviewCurrent non-invasive tests for evaluating patients with peripheral artery disease (PAD) have significant limitations for early...
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Granzyme B PET imaging inflammation and remodeling in myocardial infarction
PurposeThis study aimed to evaluate whether granzyme B (GzmB)-targeted positron emission tomography (PET) imaging agent ( 68 Ga-grazytracer) can...
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Preclinical characterisation of gallium-68 labeled ferrichrome siderophore stereoisomers for PET imaging applications
BackgroundSiderophores are small iron-binding molecules produced by microorganisms to facilitate iron acquisition from the environment. Radiolabelled...
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Prospective comparison of [18F]AlF-NOTA-octreotide PET/MRI to [68Ga]Ga-DOTATATE PET/CT in neuroendocrine tumor patients
BackgroundFluorine-18-labeled SSAs have the potential to become the next-generation tracer in SSTR-imaging in neuroendocrine tumor (NET) patients...
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18F-Choline PET/CT or PET/MR and the evaluation of response to systemic therapy in prostate cancer: are we ready?
PurposeDuring the last decade, [18F]F-choline positron emission tomography (PET) had a rising role in prostate cancer (PCa) imaging. However, despite...
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Noradrenaline transporter PET reflects neurotoxin-induced noradrenaline level decrease in the rat hippocampus
BackgroundThe neuropathological changes of early Alzheimer’s disease (AD) include neurodegenerative loss of noradrenaline neurons in the locus...
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Peptide-based PET imaging agent of tumor TIGIT expression
BackgroundAccumulating studies have demonstrated that elevated TIGIT expression in tumor microenvironment correlates with better therapeutic response...
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A comparative study of [68Ga]Ga-FAPI-04 PET/MR and [18F]FDG PET/CT in the diagnostic accuracy and resectability prediction of ovarian cancer
PurposeTo provide a theory for guiding clinical treatment by comparing the clinical application value of [ 18 F]fluorodeoxyglucose ([ 18 F]FDG) PET/CT...
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The Complementary Role of PET to Pathology in Differentiating the Primary Origin of a Malignant Skin Nodule from Liver or Lung
Metastasis from unknown primary is always a challenge because finding the true primary tumor significantly affects subsequent management. We present...
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Low TLR and PSMA-TV predict biochemical response to abiraterone acetate in metastatic prostate cancer patients develo** castration resistance after chemohormonal therapy at hormone-sensitive stage
ObjectiveTo explore whether 68 Ga-PSMA-11 PET/CT-derived parameters could predict biochemical response to abiraterone acetate (AA) treatment and...
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Comparison of 68Ga-FAPI-04 and 18F-FDG PET/CT in diagnosing ovarian cancer
PurposeThis study assesses the diagnostic performance of 68 Ga-FAPI-04 PET/CT compared to 18 F-FDG PET/CT in primary, recurrent, and metastatic...
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Optimization of an Allysine-Targeted PET Probe for Quantifying Fibrogenesis in a Mouse Model of Pulmonary Fibrosis
PurposeIdiopathic pulmonary fibrosis (IPF) is a destructive lung disease with a poor prognosis, an unpredictable clinical course, and inadequate...
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Clinical applications and prospects of PET imaging in patients with IDH-mutant gliomas
PET imaging using radiolabeled amino acids in addition to MRI has become a valuable diagnostic tool in the clinical management of patients with brain...