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A deep learning model for generating [18F]FDG PET Images from early-phase [18F]Florbetapir and [18F]Flutemetamol PET images
IntroductionAmyloid-β (Aβ) plaques is a significant hallmark of Alzheimer's disease (AD), detectable via amyloid-PET imaging. The...
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Head-to-head comparison of [18F]-Flortaucipir, [18F]-MK-6240 and [18F]-PI-2620 postmortem binding across the spectrum of neurodegenerative diseases
We and others have shown that [ 18 F]-Flortaucipir, the most validated tau PET tracer thus far, binds with strong affinity to tau aggregates in...
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Properties of [18F]FAPI monitoring of acute radiation pneumonia versus [18F]FDG in mouse models
ObjectiveIn this study, the uptake characteristics of [ 18 F]fibroblast activation protein inhibitor (FAPI) molecular imaging probe were investigated...
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Preclinical evaluation of [18F]SYN1 and [18F]SYN2, novel radiotracers for PET myocardial perfusion imaging
BackgroundPositron emission tomography (PET) is now an established diagnostic method for myocardial perfusion imaging (MPI) in coronary artery...
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A first-in-man study of [18F] FEDAC: a novel PET tracer for the 18-kDa translocator protein
PurposeN-benzyl-N-methyl-2-[7, 8-dihydro-7-(2-[ 18 F] fluoroethyl) -8-oxo-2-phenyl-9H-purin-9-yl] acetamide ([ 18 F] FEDAC) is a novel positron emission...
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Interleukin 18 and IL-18 BP response to Sars-CoV-2 virus infection
The immune response to the SARS-CoV-2 infection is crucial to the patient outcome. IL-18 is involved in the lymphocyte response to the disease and it...
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The diagnostic value of [18F]FAPI-42 PET/CT for pulmonary artery masses: comparison with [18F]FDG PET/CT
ObjectivesTo investigate the potential utility of [ 18 F]fibroblast activation protein inhibitor (FAPI) positron emission tomography/computed...
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Head-to-head comparison of 18F-FDG and 18F-FES PET/CT for initial staging of ER-positive breast cancer patients
PurposeTo compare the diagnostic performance of 18 F-fluorodeoxyglucose ( 18 F-FDG) and 18 F-fluoroestradiol ( 18 F-FES) positron emission...
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Cognitive restraint, uncontrolled eating, and emotional eating. The Italian version of the Three Factor Eating Questionnaire-Revised 18 (TFEQ-R-18): a three-step validation study
BackgroundThe Three Factor Eating Questionnaire-Revised 18 (TFEQ-R-18) is an extensively used questionnaire to measure three transdiagnostic features...
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Head-to-head comparison of 18F-FAPI and 18F-FDG PET/CT in staging and therapeutic management of hepatocellular carcinoma
BackgroundFluorine 18 ( 18 F) fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) has limitations in staging...
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18F-FACBC and 18F-FDG PET/MRI in the evaluation of 3 patients with primary central nervous system lymphoma: a pilot study
BackgroundThis PET/MRI study compared contrast-enhanced MRI, 18 F-FACBC-, and 18 F-FDG-PET in the detection of primary central nervous system...
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Content validation of the National Comprehensive Cancer Network/Functional Assessment of Cancer Therapy Lymphoma Symptom Index-18 (NFLymSI-18) in indolent B-cell non-Hodgkin’s lymphoma
BackgroundThe NFLymSI-18 is a patient-reported outcome measure comprised of the highest priority symptoms, emotional concerns, treatment side...
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Glioblastoma PET/MRI: kinetic investigation of [18F]rhPSMA-7.3, [18F]FET and [18F]fluciclovine in an orthotopic mouse model of cancer
PurposeGlioblastoma multiforme (GBM) is the most common glioma and standard therapies can only slightly prolong the survival. Neo-vascularization is...
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Optimizing adrenal vein sampling in primary aldosteronism subty** through LC–MS/MS and secretion ratios of aldosterone, 18-oxocortisol, and 18-hydroxycortisol
Adrenal venous sampling (AVS) is the gold standard for identifying curable unilateral aldosterone excess in primary aldosteronism (PA). Studies have...
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Preclinical study and first-in-human imaging of [18F]FAP-2286, and comparison with 2-[18F]FDG PET/CT in various cancer patients
PurposeFibroblast-activated protein (FAP) is highly expressed in cancer-associated fibroblasts (CAFs) of many solid cancers, but low or absent in...
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Biological and clinical roles of IL-18 in inflammatory diseases
Several new discoveries have revived interest in the pathogenic potential and possible clinical roles of IL-18. IL-18 is an IL-1 family cytokine with...
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[18F]SynVesT-1 and [18F]FDG quantitative PET imaging in the presurgical evaluation of MRI-negative children with focal cortical dysplasia type II
PurposeMRI-negative children with focal cortical dysplasia type II (FCD II) are one of the most challenging cases in surgical epilepsy management. We...
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Development, Characterization, and Radiation Dosimetry Studies of 18F-BMS-986229, a 18F-Labeled PD-L1 Macrocyclic Peptide PET Tracer
PurposeIn cancer immunotherapy, the blockade of the interaction between programmed death-1 and its ligand (PD-1:PD-L1) has proven to be one of the...
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Role of IL-18 in adipose tissue remodeling and metabolic dysfunction
Background/objectivesProinflammatory cytokines are increased in obese adipose tissue, including inflammasome key masters. Conversely, IL-18 protects...
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Clinical application of Al18F-NOTA-FAPI PET/CT in diagnosis and TNM staging of pancreatic adenocarcinoma, compared to 18F-FDG
PurposeThis study aimed to investigate the ability of Al 18 F-NOTA-FAPI PET/CT to diagnose pancreatic carcinoma and tumor-associated inflammation with...
