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Accuracy of patient-specific I-131 dosimetry using hybrid whole-body planar-SPECT/CT I-123 and I-131 imaging
PurposeThis study aimed to assess the accuracy of patient-specific absorbed dose calculations for tumours and organs at risk in radiopharmaceutical...
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CYP3A4 inhibitors may influence the quantification of [123I]I-FP-CIT SPECT scans
Purpose[ 123 I]I-FP-CIT SPECT is an imaging tool to support the diagnosis of parkinsonian syndromes characterized by nigrostriatal dopaminergic...
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The “D&I Bridge”: introducing a teaching tool to define the D, the I, and the why
Interest in learning dissemination and implementation (D&I) science is at an all-time high. As founding faculty and fellows of a new center focused...
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Effects of medication on dopamine transporter imaging using [123I]I-FP-CIT SPECT in routine practice
PurposeDopamine transporter (DAT) imaging is used to support the diagnosis of neurodegenerative parkinsonian disorders. Specific medications have...
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Correlation between remnant thyroid gland I-131 uptake and serum thyroglobulin levels: can we rely on I-131 whole body scans?
BackgroundI-131 treatment (RAI) decision relies heavily on serum thyroglobulin (Tg) levels, as higher Tg levels are assumed to be correlated with...
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DHAV 3CD targets IRF7 and RIG-I proteins to block the type I interferon upstream signaling pathway
Duck hepatitis A virus type 1 (DHAV-1) is an acute, highly lethal infectious agent that infects ducklings and causes up to 95% mortality in ducklings...
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The neurobiology of insulin-like growth factor I: From neuroprotection to modulation of brain states
After decades of research in the neurobiology of IGF-I, its role as a prototypical neurotrophic factor is undisputed. However, many of its actions in...
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Type I interferon pathway in pediatric systemic lupus erythematosus
BackgroundThe role of type I interferon (IFN-I) signaling in systemic lupus erythematosus (SLE) has been well established. However, unanswered...
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Incidental detection of acquired unilateral nasolacrimal duct obstruction on I-131 whole body scan following I-131 therapy for thyroid cancer: a case report
BackgroundRadioactive iodine 131 (I-131) is used in the treatment of differentiated thyroid cancer after thyroidectomy; however, its accumulation in...
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Biodistribution and dosimetry for combined [177Lu]Lu-PSMA-I&T/[225Ac]Ac-PSMA-I&T therapy using multi-isotope quantitative SPECT imaging
PurposeQuantitative SPECT for patient-specific dosimetry is a valuable tool in the scope of radionuclide therapy, although its clinical application...
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Prenatal diagnosis of non-typical Chiari malformation type I associated with de novo Nuclear Factor I A gene mutation: a case report
BackgroundChiari malformation is one of the most common Central nervous system (CNS) abnormalities that can be detected in routine fetal scanning....
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Safety outcomes and patients’ preferences for home-based intravenous enzyme replacement therapy (ERT) in pompe disease and mucopolysaccharidosis type I (MPS I) disorder: COVID-19 and beyond
BackgroundThe Italian Medicines Agency (AIFA) demands precise information on benefit/risk profile of home-based enzyme replacement therapy (ERT) for...
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Quantitative electroencephalography (qEEG), apolipoprotein A-I (APOA-I), and apolipoprotein epsilon 4 (APOE ɛ4) alleles for the diagnosis of mild cognitive impairment and Alzheimer’s disease
IntroductionAlzheimer’s disease (AD) is the most common type of dementia. Amnestic mild cognitive impairment (aMCI), a pre-dementia stage is an...
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Characteristics of posterior zone I retinopathy of prematurity
ObjectiveTo report the demographic profile and clinical characteristics of retinopathy of prematurity (ROP) in posterior Zone I.
Methods ...
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Development and characterization of fused human arginase I for cancer therapy
Recombinant human arginase I (rhArg I) have emerged as a potential candidate for the treatment of varied pathophysiological conditions ranging from...
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A systematic review of the potential effects of medications and drugs of abuse on dopamine transporter imaging using [123I]I-FP-CIT SPECT in routine practice
PurposeIn routine practice, dopamine transporter (DAT) imaging is frequently used as a diagnostic tool to support the diagnosis of Parkinson’s...
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Effects of injectable platelet-rich fibrin (i-PRF) on pterygium surgery with conjunctival autograft
ObjectivesTo investigate the effects of subconjunctival injectable platelet-rich fibrin (i-PRF) injection on healing and complication rates after...
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Obsessions and suicidality in youth suffering from bipolar I disorder
BackgroundObsessive compulsive disorder (OCD) is a common comorbidity with bipolar disorder, a comorbidity that is known to increase suicide risk....
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“I Am Not the Same as I Was Before”: A Qualitative Analysis of COVID-19 Survivors
BackgroundLittle is known about the illness experience of patients’ long-term emotional and physical recovery from severe COVID-19 infection. This...
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Intestinal microbiota composition of children with glycogen storage Type I patients
AimDietary therapy of glycogen storage disease I (GSD I) is based on frequent feeding, with a high intake of complex carbohydrates (supplied by...
