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Showing 1-20 of 34 results

  1. Comparison of absorbed dose extrapolation methods for mouse-to-human translation of radiolabelled macromolecules

    Background

    Extrapolation of human absorbed doses (ADs) from biodistribution experiments on laboratory animals is used to predict the efficacy and...

    Francesco Cicone, David Viertl, ... Silvano Gnesin in EJNMMI Research
    Article Open access 11 April 2022

  2. Multi-parametric PET/MRI for enhanced tumor characterization of patients with cervical cancer

    Aim

    The concept of personalized medicine has brought increased awareness to the importance of inter- and intra-tumor heterogeneity for cancer...

    Sahar Ahangari, Flemming Littrup Andersen, ... Barbara Malene Fischer in European Journal of Hybrid Imaging
    Article Open access 05 April 2022

  3. Comparison of integrin αvβ3 expression with 68Ga-NODAGA-RGD PET/CT and glucose metabolism with 18F-FDG PET/CT in esophageal or gastroesophageal junction cancers

    Background

    The primary aims of this study were to compare in patients with esophageal or esophagogastric junction cancers the potential of 68 Ga-NODAGA...

    Matthieu Dietz, Vincent Dunet, ... John O. Prior in European Journal of Hybrid Imaging
    Article Open access 01 February 2023

  5. There is a world beyond αvβ3-integrin: Multimeric ligands for imaging of the integrin subtypes αvβ6, αvβ8, αvβ3, and α5β1 by positron emission tomography

    Background

    In the context of nuclear medicine and theranostics, integrin-related research and development was, for most of the time, focused...

    Katja Steiger, Neil Gerard Quigley, ... Johannes Notni in EJNMMI Research
    Article Open access 12 October 2021

  6. Non-oncological applications of RGD-based single-photon emission tomography and positron emission tomography agents

    Introduction

    Non-invasive imaging techniques (especially single-photon emission tomography and positron emission tomography) apply several RGD-based...

    Thomas Ebenhan, Janke Kleynhans, ... Mike Sathekge in European Journal of Nuclear Medicine and Molecular Imaging
    Article 12 September 2020

  7. The aluminium-[18F]fluoride revolution: simple radiochemistry with a big impact for radiolabelled biomolecules

    The aluminium-[ 18 F]fluoride ([ 18 F]AlF) radiolabelling method combines the favourable decay characteristics of fluorine-18 with the convenience and...

    Stephen J. Archibald, Louis Allott in EJNMMI Radiopharmacy and Chemistry
    Article Open access 26 August 2021

  8. Drug conjugates for the treatment of lung cancer: from drug discovery to clinical practice

    A drug conjugate consists of a cytotoxic drug bound via a linker to a targeted ligand, allowing the targeted delivery of the drug to one or more...

    Ling Zhou, Yunlong Lu, ... Shuang Wei in Experimental Hematology & Oncology
    Article Open access 01 March 2024

  9. EANM guidance document: dosimetry for first-in-human studies and early phase clinical trials

    The numbers of diagnostic and therapeutic nuclear medicine agents under investigation are rapidly increasing. Both novel emitters and novel carrier...

    Caroline Stokke, Silvano Gnesin, ... Jonathan Gear in European Journal of Nuclear Medicine and Molecular Imaging
    Article Open access 17 February 2024

  10. First in-human radiation dosimetry of 68Ga-NODAGA-RGDyK

    Background

    Integrin-targeting radiopharmaceuticals have potential broad applications, spanning from cancer theranostics to cardiovascular diseases. We...

    Silvano Gnesin, Periklis Mitsakis, ... John O. Prior in EJNMMI Research
    Article Open access 18 May 2017

  12. PET and SPECT imaging of melanoma: the state of the art

    Melanoma represents the most aggressive form of skin cancer, and its incidence continues to rise worldwide. 18 F–FDG PET imaging has transformed...

    Weijun Wei, Emily B. Ehlerding, ... Weibo Cai in European Journal of Nuclear Medicine and Molecular Imaging
    Article 30 October 2017

  13. Radiolabelled nanoparticles for cancer diagnosis

    Purpose

    Recently, nanomedicine emerged as one of the most promising branches in biomedical field with the development of new tools for diagnostic and...

    Michela Varani, Filippo Galli, ... Alberto Signore in Clinical and Translational Imaging
    Article 25 May 2018

  16. 18th European Symposium on Radiopharmacy and Radiopharmaceuticals

    OP03 Selective extraction of medically-related radionuclides from proton-irradiated thorium targets

    V. Radchenko, J.W. Engle, C. Roy, J. Griswold,...

    V. Radchenko, J. W. Engle, ... Yann Seimbille in EJNMMI Radiopharmacy and Chemistry
    Article Open access 17 June 2016
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