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Optimization of cardiovascular risk factor management in patients with BCR::ABL1 negative chronic myeloproliferative neoplasms, current knowledge, and perspectives
The exact prognostic role of cardiovascular (CV) risk factors in patients with BCR::ABL1 negative chronic myeloproliferative neoplasms (MPNs) remains...
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Neonatal hydrocephalus: an atypical presentation of malignant infantile osteopetrosis
PurposeAutosomal recessive osteopetrosis has a variable presentation, most commonly including failure to thrive, hypocalcemia, seizures,...
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Obliterative Portal Venopathy
Purposeof ReviewTo review the clinical and histopathological features of obliterative portal venopathy (OPV).
Recent FindingsOPV is one cause of...
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The acidic domain of Hmga2 and the domain’s linker region are critical for driving self-renewal of hematopoietic stem cell
High mobility group AT-hook 2 (Hmga2) is a chromatin modifier protein that plays a critical role in fetal development and leukemia propagation by...
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Osteopetrosis in the pediatric patient: what the radiologist needs to know
Osteopetrosis describes several types of rare sclerosing bone dysplasias of varying clinical and radiographic severity. The classic autosomal...
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Nanomedicine‐boosting icaritin-based immunotherapy of advanced hepatocellular carcinoma
Traditional treatments for advanced hepatocellular carcinoma (HCC), such as surgical resection, transplantation, radiofrequency ablation, and...
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Ten years of treatment with ruxolitinib for myelofibrosis: a review of safety
Myelofibrosis (MF) is a chronic myeloproliferative neoplasm characterized by bone marrow fibrosis, anemia, extramedullary hematopoiesis, and...
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Bilateral extra-adrenal perirenal myelolipomas: a case report
BackgroundMyelolipomas are mesenchymal tumors usually involving the adrenal gland. They are a rare entity with incidence ranging from 0.08 to 0.4% as...
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Splenic red pulp macrophages provide a niche for CML stem cells and induce therapy resistance
Disease progression and relapse of chronic myeloid leukemia (CML) are caused by therapy resistant leukemia stem cells (LSCs), and cure relies on...
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Evaluation of iron overload in visceral organs in thalassemia patients by point shear-wave elastography
IntroductionThe aim of this study was to investigate the value of point shear-wave elastography (pSWE) in the measurement of iron overload in the...
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Outcome of pregnancy in women with splenomegaly
BackgroundThe spleen is a lymphopoietic organ, contains almost one quarter of the body’s lymphocytes.
MethodThis was a prospective cross sectional...
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Imaging findings of lesions in the middle and posterior mediastinum
Lesions in the middle and posterior mediastinum are relatively rare, but there are some useful radiological clues that can be used to diagnose them...
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Radiological imaging in multiple myeloma: review of the state-of-the-art
PurposeMultiple myeloma is a type of blood cancer arising from the uncontrolled clonal proliferation of malignant plasma cells resulting in impaired...
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The application of JAK inhibitors in the peri-transplantation period of hematopoietic stem cell transplantation for myelofibrosis
Myelofibrosis (MF) is a myeloproliferative neoplasm (MPN) with a poor prognosis, and allogeneic hematopoietic stem cell transplantation (allo-HSCT)...
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The role of T2*-weighted gradient echo in the diagnosis of tumefactive intrahepatic extramedullary hematopoiesis in myelodysplastic syndrome and diffuse hepatic iron overload: a case report and review of the literature
BackgroundExtramedullary hematopoiesis is the proliferation of hematopoietic cells outside bone marrow secondary to marrow hematopoiesis failure....
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SPAG6 regulates cell proliferation and apoptosis via TGF-β/Smad signal pathway in adult B-cell acute lymphoblastic leukemia
Adult B-cell acute lymphoblastic leukemia (B-ALL) prognosis remains unsatisfactory, and searching for new therapeutic targets is crucial for...
