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Zebrafish live imaging: a strong weapon in anticancer drug discovery and development
Develo** anticancer drugs is a complex and time-consuming process. The inability of current laboratory models to reflect important aspects of the...
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Sarcopenia is associated with chemoradiotherapy discontinuation and reduced progression-free survival in glioblastoma patients
PurposeSarcopenia may complicate treatment in cancer patients. Herein, we assessed whether sarcopenia measurements derived from radiation planning...
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Evaluation of Retinal Vascularity Index in Patients with COVID-19: A Case–Control Study
IntroductionThe purpose of this study was to evaluate the impact of COVID-19 infection on retinal microvasculature by topographically map** the...
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One Health Risk and Disease (OHRAD): a tool to prioritise the risks for epidemic-prone diseases from One Health perspective
BackgroundThe rise in epidemic-prone diseases daily poses a serious concern globally. Evidence suggests that many of these diseases are of animal...
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Map** high-grade glioma immune infiltration to 5-ALA fluorescence levels: TCGA data computation, classical histology, and digital image analysis
PurposeResection of high-grade gliomas has been considerably improved by 5-aminolevulinic acid (5-ALA). However, not all neurobiological properties...
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Signal Intensity Trajectories Clustering for Liver Vasculature Segmentation and Labeling (LiVaS) on Contrast-Enhanced MR Images: A Feasibility Pilot Study
AbstractThis study aims to develop a semiautomated pipeline and user interface (LiVaS) for rapid segmentation and labeling of MRI liver vasculature...
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Semi-automated computed tomography Volumetry can predict hemihepatectomy specimens’ volumes in patients with hepatic malignancy
BackgroundOne of the major causes of perioperative mortality of patients undergoing major hepatic resections is post-hepatectomy liver failure ( PHLF )...
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Software development to standardize the clinical diagnosis of exercise oscillatory ventilation in heart failure
BackgroundExercise oscillatory ventilation (EOV) is characterized by periodic oscillations of minute ventilation during cardiopulmonary exercise...
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Occurrence of Monoclonal Band in Alpha Region on Serum Electrophoresis in Multiple Myeloma: A Diagnostic Conundrum
The presence of an M-band in serum and/or urine electrophoresis is a crucial diagnostic indicator for multiple myeloma and other plasma cell...
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Changes in higher order aberrations after central corneal regularization - a comparative two-year analysis of a semi-automated topography-guided photorefractive keratectomy combined with corneal cross-linking
BackgroundThe optical quality in progressive keratoconus deteriorates due to ectasia and distortion of the corneal shape and optics. While corneal...
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ELaPro, a LOINC-mapped core dataset for top laboratory procedures of eligibility screening for clinical trials
BackgroundScreening for eligible patients continues to pose a great challenge for many clinical trials. This has led to a rapidly growing interest in...
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User-acceptability of an automated telephone call for post-operative follow-up after uncomplicated cataract surgery
BackgroundInnovative technology is recommended to address the current capacity challenges facing the NHS. This study evaluates the patient...
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ePRO symptom follow-up of colorectal cancer patients receiving oxaliplatin-based adjuvant chemotherapy is feasible and enhances the quality of patient care: a prospective multicenter study
PurposeElectronic (e) patient-reported outcomes (PROs) have been shown to improve the quality of life and survival in chemotherapy treated advanced...
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Reliability and feasibility of automated function imaging for quantification in patients with left ventricular dilation: comparison with cardiac magnetic resonance
Automated function imaging (AFI, GE Healthcare) is a novel promising algorithm of speckle-tracking echocardiography that combines two-dimensional...
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Computed tomography-based body composition parameters can predict short-term prognosis in ulcerative colitis patients
ObjectivesEmerging evidence suggests a potential relationship between body composition and short-term prognosis of ulcerative colitis (UC). Early and...
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Green analytical toxicology method for determination of synthetic cathinones in oral fluid samples by microextraction by packed sorbent and liquid chromatography–tandem mass spectrometry
PurposeWe developed and validated a method for quantitative analysis of ten synthetic cathinones in oral fluid (OF) samples, using microextraction by...
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Quantitative assessment of the troCarWash™ system for automated laparoscopic camera cleaning
BackgroundSoilage of the surgical endoscope occurs frequently during minimally invasive surgery. The resultant impairment of visualization of the...
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A rapid high-performance semi-automated tool to measure total kidney volume from MRI in autosomal dominant polycystic kidney disease
ObjectivesTo develop a high-performance, rapid semi-automated method (Sheffield TKV Tool) for measuring total kidney volume (TKV) from magnetic...
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Protocol for a systematic review and meta-analysis of the prevalence of mental illness among nursing home residents
BackgroundThere is a high prevalence of mental illness in nursing home residents compared to older adults living in the community. This was...
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Validity of cingulate–precuneus–temporo-parietal hypometabolism for single-subject diagnosis of biomarker-proven atypical variants of Alzheimer’s Disease
The aim of our study was to establish empirically to what extent reduced glucose uptake in the precuneus, posterior cingulate and/or temporo-parietal...
