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Imbalanced mucosal microcirculation in the remission stage of ulcerative colitis using probe-based confocal laser endomicroscopy
BackgroundMicrocirculatory disturbance is an important factor in the pathogenesis of Inflammatory Bowel Disease (IBD) but there have been few studies...
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Novel Strategies for Optimization of the Pre-transplant Donor Lung
Purpose of ReviewWhile the number of lung transplants continues to increase, there remains an imbalance between potential lung transplant candidates...
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Video-assisted thoracoscopic surgery (VATS) in children: single institutional, retrospective review
PurposeThe introduction of the concept of thoracoscopy is over 100 years old, but the use of thoracoscopy as a therapeutic intervention in the...
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Oral Consequences of Systemic Lupus Erythematosus: an Update
Purpose of ReviewSystemic lupus erythematosus (SLE) is an autoimmune disease affecting multiple organs that has been associated with various oral...
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Prädiktion von Krankheitsverlauf und Therapieerfolg
BackgroundAlthough the introduction of targeted therapies has led to a significant improvement in the care of patients with inflammatory bowel...
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Spectrum of congenital lung and foregut malformations: scope for awareness and prompt management—a case series
Congenital lung and foregut malformations have been described in literature, but most articles are from the Western world. There are a separate set...
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Whole blood hydroxychloroquine: Does genetic polymorphism of cytochrome P450 enzymes have a role?
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a wide range of clinical manifestations and multifactorial etiologies ranging...
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Chronic Cutaneous Lupus Erythematosus in a White Population: Dermoscopic Characteristics by Clinical Subtype, Lesion Location and Disease Duration
IntroductionChronic cutaneous lupus erythematosus (CCLE) comprises three major clinical variants: discoid lupus erythematosus (DLE), chilblain lupus...
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Cryobiopsy in Interstitial Lung Disease: Is It Prime Time?
Purpose of ReviewTransbronchial cryobiopsy (TBCB) may be used as an alternative to surgical lung biopsy (SLB) for the histopathologic evaluation of...
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A multidimensional strategy to managing dysfunctional breathing and exercise-induced laryngeal obstruction in adolescent athletes
BackgroundExercise induced laryngeal obstruction (EILO) causes inspiratory distress in the upper airway in many adolescent athletes. The nature of...
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Presbyopic lens exchange (PRELEX) cataract surgery outcomes with implantation of a rotationally asymmetric refractive multifocal intraocular lens: femtosecond laser-assisted versus manual phacoemulsification
PurposeTo compare the visual and refractive outcomes obtained with the implantation of a rotationally asymmetric refractive multifocal IOL after...
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Gastric emphysema and pneumatosis intestinalis in two common marmosets with duodenal dilation syndrome
BackgroundCommon marmosets ( Callithrix jacchus ) are widely used as primate experimental models in biomedical research. Duodenal dilation with...
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Immune responses in the irritable bowel syndromes: time to consider the small intestine
BackgroundIrritable bowel syndrome (IBS) is considered a disorder of gut-brain interaction (DGBI), presenting as chronic abdominal pain and altered...
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Real-time in vivo optical biopsy using confocal laser endomicroscopy to evaluate distal margin in situ and determine surgical procedure in low rectal cancer
BackgroundIn low rectal cancer, a negative distal margin (DM) is necessary for R0 radical resection, and therefore, the choice of surgical procedure...
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Highlighting the Undetectable — Fluorescence Molecular Imaging in Gastrointestinal Endoscopy
AbstractFlexible high-definition white-light endoscopy is the current gold standard in screening for cancer and its precursor lesions in the...
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Update on Cutaneous Signs to Assist in the Diagnosis of Dermatomyositis
Purpose of ReviewDermatomyositis (DM) is a heterogeneous idiopathic inflammatory myopathy that can be challenging to diagnose. Learning about the...
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Targeting Interferon Signalling in Systemic Lupus Erythematosus: Lessons Learned
The development of new medicines for systemic lupus erythematosus (SLE) has not addressed unmet clinical need, with only three drugs receiving...
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Visualization of the human enteric nervous system by probe confocal laser endomicroscopy: a first real-time observation of Hirschsprung’s disease and allied disorders
BackgroundOur group previously proved that the human enteric nervous system can be visualized with confocal laser endomicroscopy after topical...
