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The many faces of solitary fibrous tumor; diversity of histological features, differential diagnosis and role of molecular studies and surrogate markers in avoiding misdiagnosis and predicting the behavior
BackgroundSolitary Fibrous Tumor (SFT) is a distinct soft tissue neoplasm associated with NAB2-STAT6 gene fusion. It can involve a number of anatomic...
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Thematic research clusters in very old populations (≥ 80 years): a bibliometric approach
BackgroundPopulation aging will be one of humanity’s major challenges in the decades to come. In addition to focusing on the pathologies causing the...
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Performance of ChatGPT on the Taiwan urology board examination: insights into current strengths and shortcomings
PurposeTo compare ChatGPT-4 and ChatGPT-3.5's performance on Taiwan urology board examination (TUBE), focusing on answer accuracy, explanation...
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Evaluation of maintenance of the common androgen deprivation therapy with the new antiandrogen therapy in patients with castration-resistant prostate cancer: a systematic review
PurposeAdvanced prostate cancer does not respond to traditional androgen deprivation therapy (ADT) at some point in the treatment. The development of...
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Mixed neuroendocrine–non-neuroendocrine neoplasm of the bile duct with long-term prognosis after neoadjuvant chemotherapy
A 74-year-old man with obstructive jaundice presented with a thickened distal bile duct wall. A transpapillary forceps biopsy revealed an...
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Incidence and molecular characteristics of deficient mismatch repair conditions across nine different tumors and identification of germline variants involved in Lynch-like syndrome
BackgroundBased on molecular characteristics, deficient DNA mismatch repair (dMMR) solid tumors are largely divided into three categories:...
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Pseudosarcomatous myofibroblastic proliferations of the urinary bladder are neoplasms characterized by recurrent FN1–ALK fusions
Pseudosarcomatous myofibroblastic proliferation is a descriptive term that designates a group of clinically indolent genitourinary lesions that most...
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Management of the Devastated Bladder Outlet after Prostate CANCER Treatment
Purpose of ReviewDevastating complications of the bladder outlet resulting from prostate cancer treatments are relatively uncommon. However, the...
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Overview of the 2022 WHO Classification of Paragangliomas and Pheochromocytomas
This review summarizes the classification of tumors of the adrenal medulla and extra-adrenal paraganglia as outlined in the 5th series of the WHO...
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Primary MiNEN of the urinary bladder: an hitherto undescribed entity composed of large cell neuroendocrine carcinoma and adenocarcinoma with a distinct clinical behavior
Neuroendocrine carcinomas (NECs) of the urinary bladder are very rare and can be observed in the context of mixed neuroendocrine/non-neuroendocrine...
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Association between inflammatory bowel disease and risk of incident prostate cancer: a systematic review and meta-analysis of cohort studies
Background and objectiveNumerous observational studies have been conducted to investigate the potential association between inflammatory bowel...
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Emerging and anticipated innovations in prostate cancer MRI and their impact on patient care
Prostate cancer (PCa) remains the leading malignancy affecting men, with over 3 million men living with the disease in the US, and an estimated...
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Identifying Safety Subgroups at Risk: Assessing the Agreement Between Statistical Alerting and Patient Subgroup Risk
IntroductionIdentifying individual characteristics or underlying conditions linked to adverse drug reactions (ADRs) can help optimise the...
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Safety of Secukinumab from 1 Million Patient-Years of Exposure: Experience from Post-Marketing Setting and Clinical Trials
IntroductionSecukinumab is an anti-interleukin (IL)-17A monoclonal antibody indicated for multiple immunological disorders. Here, we aim to summarize...
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Use of artificial intelligence in discerning the need for prostate biopsy and readiness for clinical practice: a systematic review protocol
BackgroundVariability and inaccuracies in the diagnosis of prostate cancer, and the risk of complications from invasive tests, have been extensively...
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Unusual Presentation of Concurrent Cutaneous Plasmablastic Lymphoma and Acute Myeloid Leukemia: a Case Report and a Comprehensive Review
Plasmablastic lymphoma (PBL) is a rare type of non-Hodgkin’s lymphoma, primarily seen in patients with immunosuppression, particularly HIV. It...
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Clear cell adenocarcinoma of the male urethra: a case report
BackgroundPrimary urethral cancer in males is rare. Clear cell adenocarcinoma is more rare. We report a case in an African male suspected to have a...
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Clear cell renal cell carcinoma cells show diffuse expression of phagocytotic markers through the identification of lysosome-rich eosinophilic granules
BackgroundPaneth cell-like granules (PCLG) in clear cell renal cell carcinomas (RCC) have previously been reported but were not found to express...
