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Isolated Primary Mammary Tuberculosis Mimicking Breast Carcinoma
Mammary tuberculosis is one of the rare forms of extra-pulmonary tuberculosis that poses challenges in both diagnosis and management. Due to its...
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Estetrol and Mammary Gland: Friends or Foes?
Estrogens have pleiotropic effects on many reproductive and non-reproductive tissues and organs including the mammary gland, uterus, ovaries, vagina,...
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Elevated EDAR signalling promotes mammary gland tumourigenesis with squamous metaplasia
Ectodysplasin A receptor (EDAR) is a death receptor in the Tumour Necrosis Factor Receptor (TNFR) superfamily with roles in the development of hair...
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Short Term Changes in Dietary Fat Content and Metformin Treatment During Lactation Impact Milk Composition and Mammary Gland Morphology
Maternal health and diet can have important consequences for offspring nutrition and metabolic health. During lactation, signals are communicated...
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A novel targeted approach to delineate a role for estrogen receptor-β in ameliorating murine mammary tumor-associated neuroinflammation
PurposeCirculating estrogens in breast cancer patients and survivors are often extremely low due to menopause and estrogen-reducing cancer...
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Twelfth Annual ENBDC Workshop: Methods in Mammary Gland Biology and Breast Cancer
The twelfth annual workshop of the European Network for Breast Development and Cancer focused on methods in mammary gland biology and breast cancer,...
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Long-term outcomes of percutaneous revascularization for internal mammary artery–left anterior descending artery bypass failure
Despite the excellent long-term results of internal mammary artery (IMA)–left anterior descending (LAD) bypass, percutaneous revascularization of IMA...
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Regulation of a progenitor gene program by SOX4 is essential for mammary tumor proliferation
In breast cancer the transcription factor SOX4 has been shown to be associated with poor survival, increased tumor size and metastasis formation....
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Mammary gland 3D cell culture systems in farm animals
In vivo study of tissue or organ biology in mammals is very complex and progress is slowed by poor accessibility of samples and ethical concerns....
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Staphylococcus aureus mediates pyroptosis in bovine mammary epithelial cell via activation of NLRP3 inflammasome
Cell death and inflammation are intimately linked during mastitis due to Staphylococcus aureus ( S. aureus ). Pyroptosis, a programmed necrosis...
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Disruption of STAT5A and NMI signaling axis leads to ISG20-driven metastatic mammary tumors
Molecular dynamics of developmental processes are repurposed by cancer cells to support cancer initiation and progression. Disruption of the delicate...
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Comparison of the anti-cancer activity of 5-aminolevulinic acid-mediated photodynamic therapy after continuous wave and pulse irradiation in different histological types of canine mammary sarcoma tumors
Canine mammary sarcoma tumors (CMST) are the most aggressive tumors with poor prognosis in dogs. Due to inadequate treatment options for CMST,...
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Altered Epithelial-mesenchymal Plasticity as a Result of Ovol2 Deletion Minimally Impacts the Self-renewal of Adult Mammary Basal Epithelial Cells
Stem-cell containing mammary basal epithelial cells exist in a quasi-mesenchymal transcriptional state characterized by simultaneous expression of...
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DAD3 targets ACE2 to inhibit the MAPK and NF-κB signalling pathways and protect against LPS-induced inflammation in bovine mammary epithelial cells
The protective arm of the renin-angiotensin system (RAS), the ACE 2/Ang-(1–7)/MasR axis, has become a new anti-inflammatory target. As a specific...
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Internal mammary lymph node biopsy during delayed free flap breast reconstruction: case series and review of the literature
BackgroundInternal mammary vessels are often used as recipient vessels during free flap breast reconstruction, especially in delayed reconstruction....
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MiR-125b regulates inflammation in bovine mammary epithelial cells by targeting the NKIRAS2 gene
Mastitis is a complex inflammatory disease caused by pathogenic infection of mammary tissue in dairy cows. The molecular mechanism behind its...
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Evolution of HER2-positive mammary carcinoma: HER2 loss reveals claudin-low traits in cancer progression
HER2-positive breast cancers may lose HER2 expression in recurrences and metastases. In this work, we studied cell lines derived from two transgenic...
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Neurofibroma with adenosis in the mammary gland: a case report
BackgroundNeurofibroma of the breast is extremely rare, with only a few reported cases. Here, we report a case of solitary neurofibroma of the breast...