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Absolute quantification of tumor-infiltrating immune cells in high-grade glioma identifies prognostic and radiomics values
PurposeTo understand the tumor immune microenvironment precisely, it is important to secure the quantified data of tumor-infiltrating immune cells,...
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Association of tumor deposits with tumor-infiltrating lymphocytes and prognosis in gastric cancer
BackgroundTo investigate the relationship between tumor deposits (TDs) with the clinicopathological characteristics tumor-infiltrating lymphocytes...
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Stromal or intraepithelial tumor-infiltrating lymphocytes: which one has more prognostic significance in cervical cancer?
PurposeTo investigate the effect of tumor-infiltrating lymphocytes (TILs) and tumor associated macrophages (TAMs) on treatment results in patients...
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Characteristic differences in the abundance of tumor-infiltrating lymphocytes and intratumoral develo** T cells in thymoma, with special reference to PD-1 expression
PurposeThough programmed cell death-1 (PD-1) inhibitors mainly target tumor-infiltrating lymphocytes (TILs) expressing PD-1, develo** T cells in...
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IL-2 promotes expansion and intratumoral accumulation of tumor infiltrating dendritic cells in pancreatic cancer
This study aims to investigate the diagnostic potential of IL-2 for PDAC and develop a method to improve the dendritic cell (DC) based vaccine...
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High density of CXCL12-positive immune cell infiltration predicts chemosensitivity and recurrence-free survival in ovarian carcinoma
BackgroundOvarian carcinoma is the most lethal gynecologic malignancy because of its late diagnosis, extremely high recurrence rate, and limited...
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Polydatin radiosensitizes lung cancer while preventing radiation injuries by modulating tumor-infiltrating B cells
BackgroundAcquired radio-resistance and the undesired normal tissue radiation injuries seriously discount the therapeutic effect of lung cancer...
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Tumor-infiltrating OX40+ lymphocytes is an independent positive prognostic factor for patients with pancreatic ductal adenocarcinoma
PurposeOX40 signaling pathway occupies a vital place in anti-tumor immunity; however, the role of tumor-infiltrating OX40 + lymphocytes in pancreatic...
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Identification and validation of an immune-relevant risk signature predicting survival outcome and immune infiltration in uveal melanoma
PurposeThe current study aimed to reveal a novel immune-related signature to evaluate immune infiltration status and the survival outcome for...
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Potential role of immune cell therapy in gynecological cancer and future promises: a comprehensive review
Gynecological malignancies are most leading causes of death among women worldwide. The high prevalence of gynecologic malignancies remains...
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NUF2 is correlated with a poor prognosis and immune infiltration in clear cell renal cell carcinoma
BackgroundClear cell renal cell carcinoma (ccRCC) is one of the most common malignancies. Recently, immunotherapy has been considered a promising...
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18β-glycyrrhetinic acid suppresses Lewis lung cancer growth through protecting immune cells from ferroptosis
Purpose18β-glycyrrhetinic acid (GA), the main metabolite of glycyrrhizic acid extracted from the root of licorice, has been reported to possess...
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PD-L1 Expression in Colorectal Carcinoma Correlates with the Immune Microenvironment
Introduction/BackgroundColorectal carcinoma (CRC) is a common malignancy, with its diverse clinical, pathological, and molecular features. The immune...
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Unraveling T cell exhaustion in the immune microenvironment of osteosarcoma via single-cell RNA transcriptome
AbstractOsteosarcoma (OS) represents a profoundly invasive malignancy of the skeletal system. T cell exhaustion (Tex) is known to facilitate...
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New insight on the correlation of immune landscapes with immune markers expression in different risk classification of gastrointestinal stromal tumors
BackgroundThe immune landscapes of gastrointestinal stromal tumors (GISTs) are still unclear. We aimed to explore the immune status of GISTs with...
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Associations between dynamic-contrast enhanced MRI and tumor infiltrating lymphocytes and tumor-stroma ratio in head and neck squamous cell cancer
ObjectivesThe present study used dynamic-contrast enhanced MRI (DCE-MRI) to elucidate possible associations with tumor-infiltrating lymphocytes...
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The prognostic value of LAYN in HPV-related head and neck squamous cell carcinoma and its influence on immune cell infiltration
BackgroundHPV-positive head and neck squamous cell carcinoma (HNSCC) exhibits different characteristics from HPV-negative tumors in terms of tumor...
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Immune characteristics of dedifferentiated retroperitoneal liposarcomas and the reliability of regional samples in evaluating their tumor immune microenvironments
BackgroundTumor immunotherapy is a new treatment breakthrough for retroperitoneal liposarcoma (RPLS), which is highly invasive and has few effective...
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A novel pyroptosis-related gene signature exhibits distinct immune cells infiltration landscape in Wilms’ tumor
BackgroundWilms’ tumor (WT) is the most common renal tumor in childhood. Pyroptosis, a type of inflammation-characterized and immune-related...
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H19 may regulate the immune cell infiltration in carcinogenesis of gastric cancer through miR-378a-5p/SERPINH1 signaling
BackgroundIncreasing studies have indicated that noncoding RNA (ncRNA)-mediated competing endogenous RNA (ceRNA) network serves as a significant role...
