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Ovarian dysfunction in adolescent girls with autoimmune rheumatic diseases
ObjectiveTo explore the different menstrual and pubertal abnormalities in adolescent females with systemic autoimmune rheumatic diseases (ARD).
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Transition from pediatric to adult care in patients with Turner syndrome in Italy: a consensus statement by the TRAMITI project
PurposeTransition from pediatric to adult care is associated with significant challenges in patients with Turner syndrome (TS). The objective of the...
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Angiopoietin-2 levels correlates with disease activity in children with nonalcoholic fatty liver disease
BackgroundNonalcoholic fatty liver disease (NAFLD), a chronic liver disease in children, ranges from nonalcoholic fatty liver (NAFL) to nonalcoholic...
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Diagnostic accuracy of two-dimensional shear wave elastography in detecting hepatic fibrosis in children with autoimmune hepatitis, biliary atresia and other chronic liver diseases
BackgroundAlthough fibrosis is the main determinant of liver stiffness, other disease-related factors usually disregarded in studies on liver...
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Epidemiology and outcomes of pediatric autosomal recessive polycystic kidney disease in the Middle East and North Africa
The incidence of rare diseases is expected to be comparatively higher in the Middle East and North Africa (MENA) region than in other parts of the...
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Liver cirrhosis in children – the role of imaging in the diagnostic pathway
Liver cirrhosis in children is a rare disease with multifactorial causes that are distinct from those in adults. Underlying reasons include...
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Review on pediatric coeliac disease from a clinical perspective
Coeliac disease is an immune-mediated condition characterized by chronic inflammation of the small bowel with villous atrophy driven by gluten...
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Early-onset hepatic veno-occlusive disease after liver transplantation: an institutional experience and analysis of a literature-based cohort
PurposeHepatic veno-occlusive disease (HVOD) after liver transplantation (LT) is almost always a fatal complication. We assessed the outcomes of HVOD...
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Characteristics and Risk Factors for Pediatric Sepsis
ObjectiveSepsis is considered a major cause of health loss in children and had high mortality and morbidity. Currently, there is no reliable model...
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Treatment Options in Refractory Autoimmune Encephalitis
Autoimmune encephalitis represents a potentially treatable immune-mediated condition that is being more frequently recognized. Prompt immunotherapy...
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Quantitative evaluation of hepatic steatosis using attenuation imaging in a pediatric population: a prospective study
BackgroundObesity and fatty-liver disease are increasingly common in children. Hepatic steatosis is becoming the most common cause of chronic liver...
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Ibrutinib: Pediatric First Approval
Ibrutinib (IMBRUVICA ® ), a small molecule inhibitor of Bruton’s tyrosine kinase (BTK) developed by Pharmacyclics, Inc. and Janssen Pharmaceutical, is...
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Clinical and laboratory features associated with macrophage activation syndrome in Still’s disease: data from the international AIDA Network Still’s Disease Registry
To characterize clinical and laboratory signs of patients with Still’s disease experiencing macrophage activation syndrome (MAS) and identify factors...
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Seronegative autoimmune hepatitis in children
Background and aimClassical autoimmune hepatitis (AIH) is characterized by the presence of conventional autoantibodies (anti-smooth muscle,...
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Global liver transplantation: emerging trends and ethical challenges
PurposeLiver transplant (LT) is the only definitive treatment for end-stage liver disease (ESLD). This review aims to explore current global LT...
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Fibrinogen level among children with liver cirrhosis
IntroductionThe liver has a major role in the production of coagulation factors, and cirrhotic patients have a series of coagulopathy disorders. The...
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Bacterial and fungal bloodstream infections in pediatric liver and kidney transplant recipients
BackgroundBacterial and fungal bloodstream infections (BSI) are common after pediatric liver and kidney transplantations and associated with...
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Epidemiology of acute liver failure in Egyptian children
BackgroundAcute liver failure (ALF) is a serious condition that refers to the development of synthetic function impairment after severe acute liver...
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Pediatric biliary calculus disease: clinical spectrum, predisposing factors, and management outcome revisited
BackgroundBiliary calculus disease (BCD) is one of the most prevalent diseases and poses a significant burden to the health care system in adults....
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Recipient-associated risk factors for post-liver transplantation biliary complications: A cohort study
IntroductionBiliary complications (BCs) are a well-documented post-liver transplantation concern with potential implications for patient survival....
