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Impaired systemic vascular endothelial function in patients with non-arteritic anterior ischaemic optic neuropathy
PurposeThe purpose of this study was to evaluate systemic endothelial function in elderly hypertension patients with non-arteritic anterior ischaemic...
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Antenatal sildenafil administration to prevent pulmonary hypertension in congenital diaphragmatic hernia (SToP-PH): study protocol for a phase I/IIb placenta transfer and safety study
BackgroundCongenital diaphragmatic hernia is an orphan disease with high neonatal mortality and significant morbidity. An important cause for this is...
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Optical Coherence Tomography to Differentiate Papilledema from Pseudopapilledema
Purpose of ReviewMild papilledema may be difficult to distinguish by clinical observation from pseudopapilledema. An accurate diagnosis is critical...
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Biocompatibility of intravitreal injection of human mesenchymal stem cells in immunocompetent rabbits
PurposeTo evaluate the feasibility, safety, and biocompatibility of intravitreal injection of human mesenchymal stem cells (MSCs) in immunocompetent...
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The diagnostic accuracy of chromatic pupillary light responses in diseases of the outer and inner retina
PurposeTo compare the chromatic pupillary light responses (PLR) in healthy subjects with those from patients with diseases of the outer or inner...
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Visual loss and other cranial ischaemic complications in giant cell arteritis
Giant cell arteritis (GCA) is the most common form of vasculitis in individuals aged 50 years and over. GCA typically affects large and medium-sized...
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Relationship between lamina cribrosa displacement and trans-laminar pressure difference in papilledema
PurposeThe purpose of this study was to describe morphological changes in lamina cribrosa (LC), prelaminar tissue thickness (PTT) and Bruch’s...
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Central Retinal Artery Occlusion: Acute Management and Treatment
Purpose of ReviewThis review will seek to answer if advances in ophthalmic imaging and evolution of treatment modalities have shed further light on...
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Giant cell arteritis: ophthalmic manifestations of a systemic disease
BackgroundGiant cell arteritis (GCA) is a systemic granulomatous vasculitis, primarily affecting medium-large arteries. It has a predilection for the...
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Subretinal fluid is common in experimental non-arteritic anterior ischemic optic neuropathy
PurposeAnterior ischemic optic neuropathy (AION) is an important cause of acute vision loss for which several animal models exist. It has been...
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Malignant optic glioma – the spectrum of disease in a case series
PurposeMalignant optic glioma of adulthood is a rare, invasive neoplasm of the anterior visual pathway with 66 cases reported in the literature. It...
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Atypical Optic Neuritis
Classic demyelinative optic neuritis is associated with multiple sclerosis and typically carries a good prognosis for visual recovery. This disorder...
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Optic neuritis: a 5-year follow-up study of Chinese patients based on aquaporin-4 antibody status and ages
Little work has been performed on the long-term outcome of optic neuritis (ON) according to the status of aquaporin-4 antibody (AQP4-Ab) and...
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Effect of enhanced extracorporeal counterpulsation in patients with non-arteritic anterior ischaemic optic neuropathy
PurposeThe purpose is to study the effect of Enhanced Extracorporeal Counterpulsation (EECP) in patients with non-arteritic anterior ischaemic optic...
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Ischemic optic neuropathies and their models: disease comparisons, model strengths and weaknesses
Ischemic optic neuropathies (IONs) describe a group of diseases that specifically target the optic nerve and result in sudden vision loss. These...
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Assessment of functional and morphometric endpoints in patients with non-arteritic anterior ischemic optic neuropathy (NAION)
BackgroundThe primary objective of this bi-center explorative pilot study was the quantitative assessment of visual field defects and retinal nerve...
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Visual outcome of mega-dose intravenous corticosteroid treatment in non-arteritic anterior ischemic optic neuropathy – retrospective analysis
BackgroundTo date, non arteritic anterior ischemic optic neuropathy (NAION) is still incurable. We wish to evaluate the effect of intravenous (IV)...
