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HDAC5 inhibition attenuates ventricular remodeling and cardiac dysfunction
BackgroundThis study aimed to investigate the role of histone deacetylase 5 (HDAC5) in ventricular remodeling and explore the therapeutic potential...
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Novel Diagnostics for Pediatric Heart Transplant Rejection
Purpose of ReviewDiagnosis of pediatric heart transplant rejection has historically relied on endomyocardial biopsy and clinical assessment. This...
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Biventricular performance in adults with a systemic right ventricle: new insights from myocardial work analysis
To evaluate biventricular mechanics by means of echo-derived myocardial work (MW) analysis in patients with a systemic right ventricle (sRV)....
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Coronary flow velocity reserve is reduced in patients with an exaggerated blood pressure response to exercise
Coronary artery disease and cardiovascular mortality are increased in patients with an exaggerated blood pressure response to exercise. The exact...
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Association between left ventricular geometry and global myocardial work in patients with heart failure with preserved ejection fraction: assessment using strain-pressure loop
Concentric LV remodeling and hypertrophy are common structural abnormalities in patients with heart failure with preserved ejection fraction (HFpEF)...
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Acute sleep deprivation: impairment of biventricular function assesed by speckle tracking echocardiography in healthy subjects
ObjectivesSleep deprivation (SD) has been found to be associated with an increased incidence of adverse cardiovascular disease (CVD) events. The aim...
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Application of myocardial work in predicting adverse events among patients with resistant hypertension
BackgroundHypertension is the most common chronic disease and the leading risk factor for disability and premature deaths worldwide. Approximately...
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Association of Epicardial Fat with Diastolic and Vascular Functions in Children with Type 1 Diabetes
We aimed to examine the relationship between epicardial fat thickness (EFT) measured by echocardiography and cardiovascular functional parameters in...
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Vortex Formation Time is a Novel Measure for Early Detection of Diastolic Abnormalities in Adolescents with Hypertension
Pediatric hypertension (HTN) has demonstrated an upward trend in recent years. Adolescent HTN has been linked to adult HTN, cardiovascular disease,...
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Evaluating left atrial strain and left ventricular diastolic strain rate as markers for diastolic dysfunction in patients with mitral annular calcification
BackgroundMitral annular calcification (MAC) poses many challenges to the evaluation of diastolic function using standard echocardiography. Left...
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Assessment of left ventricular energy loss using vector flow map** in patients with stages 1–3 chronic kidney disease
BackgroundPatients with chronic kidney disease (CKD) experience abnormality of intracardiac blood flow status during early-stages of disease. Left...
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Impact of Weight Loss with Laparoscopic Sleeve Gastrectomy on Left Ventricular Diastolic Function: a Prospective Study
PurposeThe present study purposed to investigate the effects of weight loss with LSG on echocardiographic parameters of diastolic dysfunction in...
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Left bundle branch pacing on mechanical synchrony and myocardial work in bradycardia patients
Left bundle branch pacing (LBBP) has emerged as a novel physiological pacing method to produce narrower QRS duration, but whether it could restore...
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The value of myocardial work in assessment of ventricular function in patients with non-obstructive hypertrophic cardiomyopathy
BackgroundTo evaluate myocardial work using speckle tracking echocardiography in patients with non-obstructive hypertrophic cardiomyopathy (HCM).
...
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Bisphosphoglycerate mutase predicts myocardial dysfunction and adverse outcome in sepsis: an observational cohort study
BackgroundSepsis not only causes inflammation, but also damages the heart and increases the risk of death. The glycolytic pathway plays a crucial...
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Intrinsic Wave Velocity Propagation: A Novel Parameter for Assessing the Effect of Anthracycline Chemotherapy Agents on Cardiac Diastolic Function in Breast Cancer Patients
ObjectiveAnthracycline chemotherapeutic agents have significant cardiotoxicity. The present study emphasized the effect of anthracycline chemotherapy...
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Left ventricular myocardial performance index in prediabetic patients without coronary artery disease
BackgroundPrediabetes is considered a major risk factor for diabetes mellitus (DM), leading to microvascular and cardiovascular disorders. Myocardial...
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Cardiac effects of direct anti-viral treatment in type II diabetic patients with hepatitis C infection
BackgroundThe link between diabetes mellitus and chronic hepatitis C infection remains well established. It is estimated that up to one third of...
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Single-Beat Estimation of Ventricular Contractility
Pressure-volume loops and the end-systolic pressure-volume relationship ( E max and V 0 ) are important measures of biventricular function. To overcome...
