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The Role of Lipid-Lowering Therapy in Post-Stroke Patients: Update and Recommendations
Purpose of ReviewStroke is the second leading cause of death and disability-adjusted life years worldwide, and the global lifetime risk of stroke is...
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Neurotoxicity and safety of the rechallenge of immune checkpoint inhibitors: a growing issue in neuro-oncology practice
Neurological, immune-related adverse events (n-irAE) due to immune checkpoint inhibitors (ICI) represent a growing clinical problem in neuro-oncology...
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Unravelling the myth surrounding sterol biosynthesis as plausible target for drug design against leishmaniasis
The mortality rate of leishmaniasis is increasing at an alarming rate and is currently second to malaria amongst the other neglected tropical...
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Pharmacological potentiation of monocyte-derived dendritic cell cancer immunotherapy
Dendritic cells have been at the forefront of cancer-immunotherapy research for over 2 decades. They elicited that attention by having an...
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RHO GTPase family in hepatocellular carcinoma
RHO GTPases are a subfamily of the RAS superfamily of proteins, which are highly conserved in eukaryotic species and have important biological...
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Low utilization of statins in patients with dermatomyositis/polymyositis and hyperlipidemia: a multicenter USA-based study (2013–2023)
ObjectiveWhile the cardioprotective benefits of statins for rheumatoid arthritis (RA) patients are well-established, there might be a hesitation in...
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Clinical practice guideline for the management of lipids in adults with diabetic kidney disease: abbreviated summary of the Joint Association of British Clinical Diabetologists and UK Kidney Association (ABCD-UKKA) Guideline 2024
The contribution of chronic kidney disease (CKD) towards the risk of develo** cardiovascular disease (CVD) is magnified with co-existing type 1 or...
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Prevention of post-operative complications by using a HMG-CoA reductase inhibitor in patients undergoing one-lung ventilation for non-cardiac surgery: study protocol for a randomised controlled trial
BackgroundPostoperative pulmonary complications (PPC) and peri-operative myocardial infarction (MI) have a significant impact on the long-term...
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Heart Failure Treatment in 2023: Is There a Place for Lipid Lowering Therapy?
Purpose of ReviewAn evidence for lipid lowering therapy in heart failure is briefly summarized in this review.
Recent FindingsHeart failure therapy...
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Lipid metabolic vulnerabilities of multiple myeloma
Multiple myeloma (MM) is the second most common hematological malignancy worldwide, characterized by abnormal proliferation of malignant plasma cells...
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Targeting ferroptosis opens new avenues for the development of novel therapeutics
Ferroptosis is an iron-dependent form of regulated cell death with distinct characteristics, including altered iron homeostasis, reduced defense...
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Immunosuppressive effects of circulating bile acids in human endotoxemia and septic shock: patients with liver failure are at risk
BackgroundSepsis-induced immunosuppression is a frequent cause of opportunistic infections and death in critically ill patients. A better...
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Clinical effects of Emblica officinalis fruit consumption on cardiovascular disease risk factors: a systematic review and meta-analysis
BackgroundEmblica officinalis (EO) fruit consumption has been found to have a beneficial effect on cardiovascular disease (CVD) physiological risk...
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A randomized, double-blind, multicenter, phase III study on the efficacy and safety of a combination treatment involving fimasartan, amlodipine, rosuvastatin in patients with essential hypertension and dyslipidemia who fail to respond adequately to fimasartan monotherapy
BackgroundTo assess the efficacy and safety of a combination therapy involving fimasartan, amlodipine, and rosuvastatin in patients with essential...
