Search
Search Results
-
Comparison of radiological and pathological tumor sizes in resected non-small cell lung cancer
ObjectivesIn non-small cell lung cancer (NSCLC), T factor plays an important role in determining staging. The present study aimed to determine the...
-
Lower optimal dose of amrubicin for relapsed small-cell lung cancer: a retrospective study
BackgroundAmrubicin (AMR) is one of the most active agents for small-cell lung cancer (SCLC). However, hematologic toxicity and infection at a...
-
Efficacy and safety of PD-L1 inhibitors versus PD-1 inhibitors in first-line treatment with chemotherapy for extensive-stage small-cell lung cancer
ObjectivesProgrammed cell death-ligand 1 inhibitors plus chemotherapy (PD-L1 + Chemo) have achieved substantial progress in extensive-stage...
-
Durvalumab plus carboplatin-etoposide treatment in a patient with small-cell lung cancer on hemodialysis: a case report and literature review
Little is known about the efficacy and safety of durvalumab plus carboplatin-etoposide treatment in patients with extensive-disease (ED) small-cell...
-
Assessment of systematic inflammatory and nutritional indexes in extensive-stage small-cell lung cancer treated with first-line chemotherapy and atezolizumab
BackgroundThe present study aims to investigate the prognostic role of systematic inflammatory and nutritional indexes in extensive-stage small-cell...
-
Development of a Conceptual Model of the Patient Experience in Small Cell Lung Cancer: A Qualitative Interview Study
IntroductionSmall cell lung cancer (SCLC) is a subtype of lung cancer, the second most common cancer diagnosis worldwide. Currently, there is little...
-
Network module analysis and molecular docking-based study on the mechanism of astragali radix against non-small cell lung cancer
BackgroundMost lung cancer patients worldwide (stage IV non-small cell lung cancer, NSCLC) have a poor survival: 25%-30% patients die < 3 months....
-
Addition of Immune Checkpoint Inhibitors to Chemotherapy vs Chemotherapy Alone as First-Line Treatment in Extensive-Stage Small-Cell Lung Carcinoma: A Systematic Review and Meta-Analysis
IntroductionThe addition of immune checkpoint inhibitors (ICIs) to conventional chemotherapy (CT) as first-line treatment improves survival in...
-
Imbalance of Circulating Follicular Regulatory and Follicular Helper T Cell Subpopulations Is Associated with Disease Progression and Serum CYFRA 21-1 Levels in Patients with Non-small Cell Lung Cancer
ObjectiveThis study aimed to investigate the changes of follicular helper T (TFH) and follicular regulatory T (TFR) cell subpopulations in patients...
-
Comparative Effectiveness of Lurbinectedin for the Treatment of Relapsed Small Cell Lung Cancer in the Post-Platinum Setting: A Real-World Canadian Synthetic Control Arm Analysis
BackgroundBased on findings from a single-arm, phase 2 basket trial (NCT02454972), lurbinectedin may be an effective treatment for individuals with...
-
Data-Driven Identification of Targets for Fluorescence-Guided Surgery in Non-Small Cell Lung Cancer
PurposeIntraoperative identification of lung tumors can be challenging. Tumor-targeted fluorescence-guided surgery can provide surgeons with a tool...
-
Excellent survival of pathological N0 small cell lung cancer patients following surgery
BackgroundCurrent clinical guidelines recommend surgery only for cT1-2N0M0 small cell lung cancer (SCLC) patients. In light of recent studies, the...
-
A meta-analysis of circulating tumor DNA as a survival indicator in small cell lung cancer patients
A high level of circulating tumor DNA (ctDNA) has been linked to poor survival in patients with certain solid tumors. In spite of this, it is still...
-
Correlation between immune-related adverse events and efficacy of PD-(L)1 inhibitors in small cell lung cancer: a multi-center retrospective study
BackgroundPatients receiving PD-(L)1 inhibitors frequently encounter unusual side effects known as immune-related adverse events (irAEs). However,...
-
Clinical outcomes of left upper segmentectomy vs. lobectomy for early non-small-cell lung cancer: a nationwide database study in Japan
PurposeGiven that left upper lobe and right upper and middle lobes share a similar anatomy, segmentectomy, such as upper division and lingulectomy,...
-
Update 2021: Management of Small Cell Lung Cancer
BackgroundAccounting for 14% of lung cancer, small cell lung cancer (SCLC) is a highly aggressive neuroendocrine malignancy with rapid proliferation,...
-
Potential clinical utility of liquid biopsy in early-stage non-small cell lung cancer
BackgroundLiquid biopsy has been widely researched for early diagnosis, prognostication and disease monitoring in lung cancer, but there is a need to...
-
A CT-based radiomics nomogram for predicting the progression-free survival in small cell lung cancer: a multicenter cohort study
PurposeTo develop a radiomics nomogram based on computed tomography (CT) to estimate progression-free survival (PFS) in patients with small cell lung...
-
Programmed cell death 1 pathway inhibitors improve the overall survival of small cell lung cancer patients with brain metastases
PurposeThe objective of this study was to evaluate the safety and efficacy of immune checkpoint inhibitors in small cell lung cancer patients with...
-
Reconsidering N component of cancer staging for T1-2N0-2M0 small-cell lung cancer: a retrospective study based on multicenter cohort
BackgroundThe current nodal (pN) classification still has limitations in stratifying the prognosis of small cell lung cancer (SCLC) patients with...
