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The effects of intermittent fasting diet alone or in combination with probiotic supplementation in comparison with calorie-restricted diet on metabolic and hormonal profile in patients with polycystic ovary syndrome: study protocol for a randomized clinical trial
IntroductionPolycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in females characterized by ovulatory dysfunction,...
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A systematic review and meta-analysis investigating the relationship between metabolic syndrome and the incidence of thyroid diseases
PurposeTo assess the prospective association between metabolic syndrome (MetS), its components, and incidence of thyroid disorders by conducting a...
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Skin advanced glycation end-products as indicators of the metabolic profile in diabetes mellitus: correlations with glycemic control, liver phenotypes and metabolic biomarkers
IntroductionThe production of advanced glycation end-products (AGEs) is a key pathomechanism related to the complications of diabetes mellitus. The...
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Metabolic Bone Disease in Children With Transfusion-Dependent Thalassemia
ObjectiveThis study aimed to detect metabolic bone disease and endocrinopathies in a cohort of patients with transfusion-dependent thalassemia (TDT).
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Exploring the Effects of Endocrine-Disrupting Chemicals and miRNA Expression in the Pathogenesis of Endometriosis by Unveiling the Pathways: a Systematic Review
Endometriosis, characterized by endometrial-like mucosal tissue outside the uterine cavity, is a reproductive disorder afflicting about 10% of women...
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Second-generation antipsychotic medications and metabolic disturbance in children and adolescents
BackgroundThe second-generation antipsychotics (SGAs) are a group of antipsychotic drugs, used to treat psychiatric conditions. SGAs have been shown...
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Endocrine disrupting chemicals: effects on pituitary, thyroid and adrenal glands
BackgroundIn recent years, scientific research has increasingly focused on Endocrine Disrupting Chemicals (EDCs) and demonstrated their relevant role...
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The prevalence and clinical correlates of medical disorders comorbidities in patients with bipolar disorder
ObjectiveMedical disorders in patients with bipolar disorder (BD) have attracted more and more attention. So far, there is still a lack of studies on...
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Metabolic actions of the growth hormone-insulin growth factor-1 axis and its interaction with the central nervous system
The growth hormone/insulin growth factor-1 axis is a key endocrine system that exerts profound effects on metabolism by its actions on different...
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Hypothalamic-Ovarian axis and Adiposity Relationship in Polycystic Ovary Syndrome: Physiopathology and Therapeutic Options for the Management of Metabolic and Inflammatory Aspects
Purpose of ReviewThe goal of the present review is to address the main adiposity-related alterations in Polycystic Ovary Syndrome (PCOS) focusing on...
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Acetyl-l-Carnitine Ameliorates Metabolic and Endocrine Alterations in Women with PCOS: A Double-Blind Randomized Clinical Trial
IntroductionPolycystic ovary syndrome (PCOS) is a common endocrine-metabolic disorder and the main cause of infertility in women of reproductive age....
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Influence of COVID-19 vaccines on endocrine system
The COVID-19 pandemic has posed a significant health threat globally. Timely and appropriate vaccination is a key step to reduce the morbidity and...
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Adiponectin blood levels and autism spectrum disorders: a systematic review
ObjectiveTo review the relationship between adiponectin levels and autism spectrum disorders (ASDs) in children.
BackgroundASDs are associated with...
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Ketogenic nutritional therapy (KeNuT)—a multi-step dietary model with meal replacements for the management of obesity and its related metabolic disorders: a consensus statement from the working group of the Club of the Italian Society of Endocrinology (SIE)—diet therapies in endocrinology and metabolism
PurposeThe ketogenic nutritional therapy (KeNuT) is an effective dietary treatment for patients with obesity and obesity-related comorbidities,...
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The impact of long non-coding RNA H19 on metabolic features and reproductive phenotypes of Egyptian women with polycystic ovary syndrome
BackgroundPolycystic ovary syndrome (PCOS) is known as the most common endocrine/metabolic disorder in women of reproductive age. Long non-coding...
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Metabolic and feeding adjustments during pregnancy
Eating behaviours are determined by the integration of interoceptive and environmental inputs. During pregnancy, numerous physiological adaptations...
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Health services for substance use disorders: challenges and future perspectives
Research on the health services’ response to substance use disorders and respective comorbidities holds major relevance due to the increasing...
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Influence of metabolic state and body composition on the action of pharmacological treatment of migraine
Migraine is a disabling neurovascular disorder among people of all ages, with the highest prevalence in the fertile years, and in women. Migraine...
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Towards a multilevel model of major depression: genes, immuno-metabolic function, and cortico-striatal signaling
Biological assay and imaging techniques have made visible a great deal of the machinery of mental illness. Over fifty years of investigation of mood...
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Multi-system diseases and death trajectory of metabolic dysfunction-associated fatty liver disease: findings from the UK Biobank
BackgroundMetabolic dysfunction-associated fatty liver disease (MAFLD) is a newly defined condition encompassing hepatic steatosis and metabolic...
