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Cardioprotective effects of Rhododendron arboreum leaf extract against Doxorubicin-induced cardiotoxicity in Wistar rats by modulating electrocardiographic and cardiac biomarkers
BackgroundCardiotoxicity and related complications are well-known adverse effects of anticancer drugs like doxorubicin (DOX). A medicinal plant...
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Two cases of dermatomyositis associated with neuroendocrine tumors
Dermatomyositis is an idiopathic inflammatory myopathy with cutaneous manifestations, which is associated with several types of malignancies, yet it...
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Neuroleptic malignant syndrome with acute renal failure associated with rhabdomyolysis: a case report
Neuroleptic malignant syndrome is a rare, life-threatening neurologic emergency characterized by fever, rigidity, autonomic instability, mental...
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Janus kinase-targeting therapies in rheumatology: a mechanisms-based approach
The four Janus kinase (JAK) proteins and seven signal transducer and activator of transcription (STAT) transcription factors mediate intracellular...
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Increased creatine demand during pregnancy in Arginine: Glycine Amidino-Transferase deficiency: a case report
BackgroundCreatine (Cr), an amino acid derivative, is one of the most important sources of energy acting as both a spatial and temporal energy buffer...
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Establishment of a differential diagnosis method and an online prediction platform for AOSD and sepsis based on gradient boosting decision trees algorithm
ObjectiveThe differential diagnosis between adult-onset Still’s disease (AOSD) and sepsis has always been a challenge. In this study, a machine...
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Cardioprotective role of royal jelly in the prevention of celecoxib-mediated cardiotoxicity in adult male albino rats
BackgroundCelecoxib, a cyclooxygenase-2 selective inhibitor non-steroidal anti-inflammatory drugs, is used for the management of short- and long-term...
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A nomogram model for predicting intramyocardial hemorrhage post-PCI based on SYNTAX score and clinical features
ObjectiveThe aim of this study is to develop a nomogram model for predicting the occurrence of intramyocardial hemorrhage (IMH) in patients with...
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Analysis of risk factors for acute kidney injury in children with severe wasp stings
BackgroundAcute kidney injury (AKI) is common in children with sepsis, chronic kidney disease, poisoning or other conditions. Wasp stings are...
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Short-term co-ingestion of creatine and sodium bicarbonate improves anaerobic performance in trained taekwondo athletes
BackgroundCreatine (CR) and sodium bicarbonate (SB) alone improve anaerobic performance. However, the ergogenic effects of CR and SB co-ingestion on...
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Metabolomics Profiling Predicts Ventricular Arrhythmia in Patients with an Implantable Cardioverter Defibrillator
Implantable cardioverter defibrillators (ICDs) reduce sudden cardiac death (SCD) when patients experience life-threatening ventricular arrhythmias...
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Evaluation of combination treatment with DS-1205c, an AXL kinase inhibitor, and osimertinib in metastatic or unresectable EGFR-mutant non-small cell lung cancer: results from a multicenter, open-label phase 1 study
The objective of this study was to evaluate the safety and tolerability of DS-1205c, an oral AXL-receptor inhibitor, in combination with osimertinib...
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Matching-Adjusted Indirect Comparison of Brexucabtagene Autoleucel (ZUMA-2) and Pirtobrutinib (BRUIN) in Patients with Relapsed/Refractory Mantle Cell Lymphoma Previously Treated with a Covalent Bruton Tyrosine Kinase Inhibitor
IntroductionPatients with relapsed/refractory (R/R) mantle cell lymphoma (MCL) often require multiple lines of treatment and have a poor prognosis,...
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An undifferentiated cause of rhabdomyolysis: a case report
BackgroundRhabdomyolysis can occur secondary to infections, trauma, or myotoxic substances. Rhabdomyolysis secondary to autoimmune myositis occurs...
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Blood-Based Biomarkers for Managing Workload in Athletes: Considerations and Recommendations for Evidence-Based Use of Established Biomarkers
Blood-based biomarkers can provide an objective individualized measure of training load, recovery, and health status in order to reduce injury risk...
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Dietary creatine intake and depression risk among U.S. adults
Creatine monohydrate is actively being researched for its antidepressant effects, yet little is known about the link between dietary creatine and...
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Excimer laser coronary angioplasty versus manual aspiration thrombectomy in patients with ST-segment elevation myocardial infarction: analyzed by nuclear scintigraphy
Clinical outcomes concerning the efficacy of excimer laser coronary angioplasty (ELCA) in real-world cases of acute myocardial infarction (MI) are...
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Comparison of clinical characteristics and disease burden of febrile seizures in children with and without COVID-19
BackgroundFebrile seizures (FS) are the most common seizure disorder in children and a common neurologic complication in children with coronavirus...
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Long-term follow-up results and treatment outcomes of children and adults with resistance to thyroid hormone alpha
PurposeResistance to thyroid hormone alpha (RTHα) is a rare entity and has no specific treatment. To date, mostly levothyroxine has been used, but...
