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Characterization of carotid plaques using chemical exchange saturation transfer imaging
PurposeThe preoperative assessment of carotid plaques is necessary to render revascularization safe and effective. The aim of this study is to...
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Morphological examination of the visual system and orbital region in the red panda (Ailurus fulgens fulgens)
ObjectivesThe red panda is currently the only surviving member of the Ailuridae family in the Caniformia suborder. In this study, we provide data on...
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The use of real time strain endometrial elastosonography plus endometrial thickness and vascularization flow index to predict endometrial receptivity in IVF treatments: a pilot study
BackgroundThe usefulness of endometrium strain elastosonography (SE) for the evaluation of endometrial receptivity in women undergoing in vitro...
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Identification of established and novel extracellular matrix components in glioblastoma as targets for angiogenesis and prognosis
Glioblastomas (GBM) are aggressive tumors known for their heterogeneity, rapid proliferation, treatment resistance, and extensive vasculature....
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Periostin as a blood biomarker of muscle cell fibrosis, cardiomyopathy and disease severity in myotonic dystrophy type 1
Background and purposeMyotonic dystrophy type 1 (DM1) is the most common form of adult-onset muscular dystrophy and is caused by an repeat expansion...
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Integrated plasma proteomics and lung transcriptomics reveal novel biomarkers in idiopathic pulmonary fibrosis
BackgroundIdiopathic pulmonary fibrosis (IPF) is a fatal lung disease with a significant unmet medical need. Development of transformational...
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Microneedling in the Treatment of Post-burn Hypertrophic Scars
IntroductionPost-burn hypertrophic scars are an important cause of physical discomfort, limitation of movements, psychological disorders, low...
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Endotrophin, an extracellular hormone, in combination with neoepitope markers of von Willebrand factor improves prediction of mortality in the ECLIPSE COPD cohort
BackgroundLung epithelial damage, activation of the wound healing cascade, and remodeling of the extracellular matrix (ECM) play a major role in...
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Treatment of Stretch Marks Using a New Formulation Combining Nanofractional Radiofrequency Plus Magnetic Nanofractional Radiofrequency
IntroductionStretch marks are common atrophic dermal scars with significant physical and psychological effects. Therefore, there is a need for...
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Wet Versus Dry Temporalis Fascia Graft in Type 1 Tympanoplasty: A Randomized Study on Controversy
Aim-To evaluate and compare the success rate of dry and wet temporalis fascia graft in tympanoplasty type I using an underlay technique and determine...
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Role of obesity related inflammation in pathogenesis of peripheral artery disease in patients of type 2 diabetes mellitus
ObjectiveType 2 diabetes mellitus (T2DM) has emerged as one of the greatest global health challenges of twenty-first century. Visceral obesity is one...
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New clinical classification of stiff skin syndrome
BackgroundStiff skin syndrome (SSS) is a rare disease characterized by thickened, indurated skin and limited joint movement. Multiple diverse...
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Zanubrutinib-lenalidomide-rituximab (ZR2) in unfit diffuse large B-cell lymphoma: efficient and tolerant
The objective of this study is to examine the effectiveness and safety of zanubrutinib, rituximab, and lenalidomide (ZR 2 ) in unfit patients with...
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Distal Arthrogryposis type 5 in an Italian family due to an autosomal dominant gain-of-function mutation of the PIEZO2 gene
BackgroundArthrogryposis multiplex congenita (AMC) is a group of clinically and etiologically heterogeneous conditions, characterized by prenatal...
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Intravaginal nonablative radiofrequency in the treatment of genitourinary syndrome of menopause symptoms: a single-arm pilot study
BackgroundGenitourinary syndrome of menopause (GSM) involves vaginal dryness (VD), pain during sexual activity (SAPain), vaginal itching (VI),...
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Diagnostic utility of CSF1 immunohistochemistry in tenosynovial giant cell tumor for differentiating from giant cell-rich tumors and tumor-like lesions of bone and soft tissue
BackgroundTenosynovial giant cell tumor (TSGCT) is a benign fibrohistiocytic tumor that affects the synovium of joints, bursa, and tendon sheaths and...
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Genome analysis of multidrug resistant Enterococcus faecium and Enterococcus faecalis circulating among hospitalized patients in uMgungundlovu District, KwaZulu-Natal, South Africa
BackgroundVancomycin-resistant enterococci (VRE) are important pathogens categorized as high-priority bacteria in the Global Priority List of...
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Extracellular matrix-derived mechanical force governs breast cancer cell stemness and quiescence transition through integrin-DDR signaling
The extracellular matrix (ECM) serves as signals that regulate specific cell states in tumor tissues. Increasing evidence suggests that extracellular...
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Establishment of a bi-layered tissue engineered conjunctiva using a 3D-printed melt electrowritten poly-(ε-caprolactone) scaffold
PurposeTo utilize melt electrowriting (MEW) technology using poly-(ε-caprolactone) (PCL) coupled with a 2-step co-culturing strategy for the...
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Extracellular matrix stiffness and tumor-associated macrophage polarization: new fields affecting immune exclusion
In the malignant progression of tumors, there is deposition and cross-linking of collagen, as well as an increase in hyaluronic acid content, which...
