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Dual-Energy X-Ray Absorptiometry Derived Adiposity Measures and Pre-Frailty/Frailty among Norwegian Adults: The Tromsø Study 2007–2015
ObjectivesAging is associated with changes in body composition. Excess adiposity among older adults has been linked with metabolic syndromes and...
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Emerging Evidence on the Use of Probiotics and Prebiotics to Improve the Gut Microbiota of Older Adults with Frailty Syndrome: A Narrative Review
BackgroundThe gut microbiota can impact older adults’ health, especially in patients with frailty syndrome. Understanding the association between the...
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Frailty is not an independent risk factor for worse clinical outcomes in lumbar spinal surgery: a prospective cohort study
PurposeRecently, many studies revealed that frailty affects unfavorably on postoperative outcomes in lumbar spinal diseases. This study aimed to...
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Assessing frailty amongst older people admitted to hospital in a low-income setting: a multicentre study in northern Tanzania
BackgroundPopulations are ageing globally and Low- and Middle-Income Countries (LMICs) are experiencing the fastest rates of demographic change. Few...
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Symptomatic and preventive medication use according to age and frailty in Australian and Japanese nursing homes
ObjectiveTo investigate symptomatic and preventive medication use according to age and frailty in Australian and Japanese nursing homes (NHs).
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Validation of the questionnaire for medical checkup of old-old (QMCOO) score cutoff to diagnose frailty
BackgroundFrailty is a state of increased vulnerability to poor resolution of homeostasis following a stress. Early diagnosis and intervention of...
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The role of frailty in the relationships between social relationships and health outcomes: a longitudinal study
BackgroundSocially isolated older adults incur increased risks of adverse health outcomes, though the strength of this association is unclear. We...
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Use of a wearable accelerometer to evaluate physical frailty in people receiving haemodialysis
BackgroundPhysical frailty is a major health concern among people receiving haemodialysis (HD) for stage-5 chronic kidney disease (CKD-5). Wearable...
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Transitions of self-management behaviors and frailty status among community-dwelling older adults: a national longitudinal population-based cohort study
BackgroundFrailty in older adults is a common geriatric syndrome that could be prevented; thus, co** strategies for the aging population are...
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Interaction between hypertension and frailty and their impact on death risk in older adults: a follow-up study
BackgroundHypertension and frailty often occur concurrently, exhibiting increasing prevalence in the older population. In this study, we analyzed the...
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Leveraging network analysis to determine sex differences in factors associated with frailty among older adults living alone
BackgroundFrailty is a complex geriatric syndrome typically characterized by multiple underlying etiological factors. We determined the contributing...
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Frailty-aware care: giving value to frailty assessment across different healthcare settings
Healthcare systems need to adapt to better serve an aging population with complex presentations. Frailty assessments are a potential means to address...
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The mediating effect of nutrition on oral frailty and fall risk in community-dwelling elderly people
BackgroundPopulation aging is accelerating, particularly in Asian countries. Falls are the leading cause of unintentional injuries in the elderly...
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Relationship between frailty and methotrexate discontinuation due to adverse events in rheumatoid arthritis patients
IntroductionMethotrexate (MTX) is an anchor drug in the treatment of rheumatoid arthritis (RA). Frailty is the intermediate condition between being...
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Relationship between physical activity and perceptions of ageing from the perspective of healthy ageing among older people with frailty with chronic disease: a cross-sectional study
BackgroundIn Taiwan, the 2019 Elderly Frailty Assessment found that 11.2% of older people have frailty problems. Some researchers have found that...
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Physical frailty, genetic predisposition, and incident dementia: a large prospective cohort study
Physical frailty and genetic factors are both risk factors for increased dementia; nevertheless, the joint effect remains unclear. This study aimed...
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Rheumatoide Arthritis und Sarkopenie: Gibt es Superfood gegen Frailty?
Frailty has its biomedical causes. One of the core components of frailty is the age-related loss of muscle mass or sarcopenia. In addition to...
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Pan-immune inflammation value; a novel biomarker reflecting inflammation associated with frailty
BackgroundFrailty is suggested to be associated with age-related changes in the immune system, namely immunosenescence. Few studies have investigated...
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Diet quality from mid to late life and its association with physical frailty in late life in a cohort of Chinese adults
BackgroundIt is unclear if improving diet quality after midlife could reduce the risk of physical frailty at late life. We aimed to associate changes...
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Vitamin K insufficiency predicts incidence of frailty in community-dwelling older adults: The Otassha Study
IntroductionVitamin K is a fat-soluble vitamin discovered as an essential factor for blood coagulation. It is suggested that vitamin K can benefit...