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Comprehensive Parent–Metabolite PBPK/PD Modeling Insights into Nicotine Replacement Therapy Strategies
BackgroundNicotine, the pharmacologically active substance in both tobacco and many electronic cigarette (e-cigarette) liquids, is responsible for...
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The prevalence of smoking, second-hand smoke exposure, and knowledge of the health hazards of smoking among internal migrants in 12 provinces in China: a cross-sectional analysis
BackgroundPrevious studies have provided inconsistent findings on smoking among migrants, and very limited data exist on their second-hand smoke...
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Associations among drinking water quality, dyslipidemia, and cognitive function for older adults in China: evidence from CHARLS
BackgroundThe current study aimed to examine the association between drinking water quality and cognitive function and to identify the direct and...
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The number of risk factors increases the recurrence events in ischemic stroke
PurposeStroke is a significant cause of disability worldwide and is considered a disease caused by long-term exposure to lifestyle-related risk...
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Comparison of brain nicotine uptake from electronic cigarettes and combustible cigarettes
Brain accumulation rate and magnitude are critical for the acute reinforcing effects of nicotine. Despite electronic cigarettes’ (E-cigs) appeal as...
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Epidemiological, clinical and aetiological aspects of otalgia at the Renaissance University Hospital
BackgroundOtalgia is a frequent reason for medical consultation. In Africa, few studies have been devoted to the epidemiology and aetiology of...
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Foveal macular pigment dip in offspring of age-related macular degeneration patients is inversely associated with omega-3 index
BackgroundOffspring of parent(s) with age-related macular degeneration (AMD) have a 45% lifetime risk of develo** the disease. High foveal macular...
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Evaluation of a Novel Microfocused Ultrasound with Three‐Dimensional Digital Imaging for Facial Tightening: A Prospective, Randomized, Controlled Trial
BackgroundThe excellent efficacy is mitigated by the limited safety profile of microfocused ultrasound procedures.
ObjectiveWe sought to assess the...
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Relationship between disability and psychiatric outcome in multiple sclerosis patients and its determinants
BackgroundMultiple sclerosis (MS) is an inflammatory demyelinating central nervous system disease with diverse clinical manifestations. The present...
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The diagnostic utility of squash smear cytology in lung malignancies
BackgroundLung malignancy is the most common cause of death worldwide. The main role of pathologist is to differentiate small cell from other cell...
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Incidence Trends of Gastric Cancer in Southern Iran: Adenocarcinoma and Non-cardia Gastric Cancer Are More Rising Among Younger Ages
BackgroundGastric Cancer (GC) is still one of the major causes of cancer mortality. Due to health-related transitions, the epidemiology of GC...
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The effect of day-long mask wearing on non-invasive break-up time
PurposeThis study aimed to investigate the effect of day-long face mask wearing on non-invasive tear break-up time (NI-BUT) in health care staff due...
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Impact of ambient air pollution exposure during pregnancy on adverse birth outcomes: generalized structural equation modeling approach
BackgroundAir pollution and several prenatal factors, such as socio-demographic, behavioural, physical activity and clinical factors influence...
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Incident cardiac arrhythmias associated with metabolic dysfunction-associated steatotic liver disease: a nationwide histology cohort study
BackgroundPrior studies suggest a link between metabolic dysfunction-associated steatotic liver disease (MASLD) and incident arrhythmias, including...
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Cancer among syrian refugees living in Konya Province, Turkey
BackgroundWith more than 3.6 million Syrian refugees Turkey hosts the world's largest number of Syrians. Considering the morbidity, mortality, and...
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Does implant placement using a minimally invasive technique increase early failures among trainees at an academic center?
PurposeThis study aims to identify whether dental implants placed using a flapless technique have a higher early failure rate, defined as failure...
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Target trial emulation of aspirin after diagnosis of colorectal polyps
Backgound and AimsPrevious research on the potential chemoprotective effect of aspirin for colorectal cancer (CRC) shows conflicting results. We...
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Clinical features, etiology, and prognosis of hand knob stroke: a case series
BackgroundHand knob stroke is a rare clinical disorder frequently misdiagnosed as peripheral neuropathy. The purpose of this study is to recognize...
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Comparison of clinician diagnosis of COVID-19 with real time polymerase chain reaction in an adult-representative population in Sweden
BackgroundDue to the high transmissibility of SARS-CoV-2, accurate diagnosis is essential for effective infection control, but the gold standard,...
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Endoscopic endonasal marsupialization of rathke cleft cysts: clinical outcomes and risk factors analysis of visual impairment, pituitary dysfunction, and CSF leak
ObjectiveThis paper assesses the clinical and imaging characteristics, histopathological findings, and treatment outcomes of patients with Rathke’s...