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Headache Management in the Neuroscience Intensive Care Unit
Purpose of ReviewHeadache is a common symptom in the Neuroscience Intensive Care Unit (NeuroICU). Our goal is to provide an overview of approaches to...
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Schwierig zu behandelnde chronische Rhinosinusitis – wenn die Standardtherapie nicht wirkt und Biologika nicht zur Verfügung stehen
BackgroundIn recent years, significant improvements have been made in the treatment options for uncontrolled chronic rhinosinusitis (CRS) refractory...
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The use of biologics in patients suffering from chronic rhinosinusitis with nasal polyps – a 4-year real life observation
PurposeAntibody therapy for chronic rhinosinusitis with nasal polyps (CRSwNP) has been established in Germany since 2019. With limited long-term data...
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Multidisciplinary Decision-Making—ITAlian Consensus After Two Years of Real Practice on the Management of Severe Uncontrolled CRSwNP by Biologics (ITACA Study)
Purpose of ReviewWe aimed to reach an Italian multidisciplinary consensus on some crucial aspects of treatment decision making in CRSwNP, following...
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Canadian real-world study of access and clinical results using dupilumab for chronic rhinosinusitis with polyps
BackgroundDupilumab is the first monoclonal antibody therapy to be approved in Canada for the treatment of Chronic Rhinosinusitis with Nasal Polyps...
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Dupilumab (Dupixent®) tends to be an effective therapy for uncontrolled severe chronic rhinosinusitis with nasal polyps: real data of a single-centered, retrospective single-arm longitudinal study from a university hospital in Germany
IntroductionChronic rhinosinusitis with nasal polyps (CRSwNP) is an inflammatory disease, which is usually type 2-mediated in the western hemisphere,...
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Type 2 and Non-type 2 Inflammation in the Upper Airways: Cellular and Molecular Alterations in Olfactory Neuroepithelium Cell Populations
Purpose of ReviewNeurogenesis occurring in the olfactory epithelium is critical to continuously replace olfactory neurons to maintain olfactory...
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Artificial Intelligence: Exploring the Future of Innovation in Allergy Immunology
Purpose of ReviewArtificial intelligence (AI) has increasingly been used in healthcare. Given the capacity of AI to handle large data and complex...
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C1-C2 subluxation in enthesitis-related arthritis: two case reports and literature review of ten cases
BackgroundC1-C2 subluxation is a rare complication of enthesitis-related arthritis (ERA). If left untreated, it may lead to functional impairment or...
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Pediatric Pericarditis: Update
Purpose of ReviewWhile there have now been a variety of large reviews on adult pericarditis, this detailed review specifically focuses on the...
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Tophaceous gout in a young man with Gitelman syndrome: a case report with an overview
Gitelman syndrome represents the clinical manifestations of inactivation of the Slc12a3 genes encoding the thiazide-sensitive sodium chloride...
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Entscheidungsfindung bei der Behandlung der chronischen Rhinosinusitis mit Nasenpolypen in der Ära der Biologika
Chronic rhinosinusitis is one of the most common chronic diseases in the population. Chronic rhinosinusitis with nasal polyps (CRSwNP) in adults is...
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Indicating biologics for chronic rhinosinusitis with nasal polyps (CRSwNP)
BackgroundChronic rhinosinusitis with nasal polyps (CRSwNP), an inflammatory disease of the paranasal mucosa, is primarily characterized by type 2...
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Clinical Evidence of Type 2 Inflammation in Non-allergic Rhinitis with Eosinophilia Syndrome: a Systematic Review
Purpose of ReviewNon-allergic rhinitis (NAR) includes different subtypes, among which NAR with eosinophilia syndrome (NARES) is the most important...
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The co-occurrence of SAT, hypophysitis, and Schnitzler syndrome after COVID-19 vaccination: the first described case
Subacute thyroiditis (also known as granulomatous thyroiditis, giant cell thyroiditis, de Quervain's disease, or SAT) is an inflammatory disease of...
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Potential Long-Term Health Problems Associated with Ultra-Endurance Running: A Narrative Review
It is well established that physical activity reduces all-cause mortality and can prolong life. Ultra-endurance running (UER) is an extreme sport...
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Integrating pharmacogenomics into precision pain management
Studies suggest wide heterogeneity in pain management response. Improved methods of pain pharmacotherapy are urgently needed to improve clinical...