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Effect of the interaction between the visceral-to-subcutaneous fat ratio and aldosterone on cardiac function in patients with primary aldosteronism
Primary aldosteronism is the most frequent secondary hypertensive disease and is characterized by an elevated risk for cardiovascular disease. The...
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Dynamic pressure–volume loop analysis by simultaneous real-time cardiovascular magnetic resonance and left heart catheterization
BackgroundLeft ventricular (LV) contractility and compliance are derived from pressure–volume (PV) loops during dynamic preload reduction, but...
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Evaluating the characteristics of myocardial work by two-dimensional echocardiography during pre-eclampsia pregnancy
This study aimed to analyze the changes in myocardial work (MyW) properties and the correlation of MyW with cardiovascular and clinical indices...
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Clinical genetic testing in four highly suspected pediatric restrictive cardiomyopathy cases
BackgroundRestrictive cardiomyopathy (RCM) presents a high risk for sudden cardiac death in pediatric patients. Constrictive pericarditis (CP)...
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Vortex formation time in female athletes
Regular, vigorous physical activity can have a significant impact on cardiac function, leading to cardiac morphological alterations that may be...
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Evaluation of left ventricular function by vector flow map** in females with systemic lupus erythematosus
ObjectivesCompare the intraventricular hemodynamics of 60 females with systemic lupus erythematosus (SLE) and 61 healthy female controls, and...
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Association of clinical, laboratory and imaging biomarkers with the occurrence of acute myocardial infarction in patients without standard modifiable risk factors – rationale and design of the “Beyond-SMuRFs Study”
BackgroundAcute myocardial infarction (AMI) remains the leading cause of mortality worldwide. The majority of patients who suffer an AMI have a...
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The assessment of left ventricular diastolic function: guidance and recommendations from the British Society of Echocardiography
Impairment of left ventricular (LV) diastolic function is common amongst those with left heart disease and is associated with significant morbidity....
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Noninvasive right ventricular work in patients with atrial septal defects: a proof-of-concept study
BackgroundNoninvasive right ventricular (RV) myocardial work (RVMW) determined by echocardiography is a novel indicator used to estimate RV systolic...
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Correlation between echocardiographic estimation of right atrial pressure and invasive measurement of central venous pressure in postoperative pediatric patients with congenital heart disease: a prospective observational study
BackgroundRight atrial pressure plays a critical role as a hemodynamic parameter in diagnosing pulmonary hypertension and other cardiac diseases, as...
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Physiological Impact of Afterload Reduction on Cardiac Mechanics and Coronary Hemodynamics Following Isosorbide Dinitrate Administration in Ischemic Heart Disease
AbstractUnderstanding the cardiac-coronary interaction is fundamental to develo** treatment strategies for ischemic heart disease. We sought to...
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Sacubitril/valsartan inhibits obesity-associated diastolic dysfunction through suppression of ventricular-vascular stiffness
ObjectiveCardiac diastolic dysfunction (DD) and arterial stiffness are early manifestations of obesity-associated prediabetes, and both serve as risk...
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Effect of Empagliflozin and Pioglitazone on left ventricular function in patients with type two diabetes and nonalcoholic fatty liver disease without established cardiovascular disease: a randomized single-blind clinical trial
BackgroundNonalcoholic fatty liver disease (NAFLD) is a complex metabolic disorder that increases the risk for cardiovascular disease in patients...
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Pressure–Strain Loops, a Novel Non-invasive Approach for Assessment of Children with Cardiomyopathy
Non-invasive myocardial work (MW) by left ventricular (LV) pressure–strain loops (PSL) is a novel method for assessing myocardial function while...
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Evaluation of cardiac fibrosis and subclinical cardiac changes in children with sickle cell disease using magnetic resonance imaging, echocardiography, and serum galectin-3
BackgroundMyocardial fibrosis has recently been proposed as one of the contributing factors to the diverse pathogenicity of cardiomyopathy in sickle...
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Tei Index and its Relation to Outcome of Critically Ill Children on Continuous Renal Replacement Therapy
ObjectivesTo evaluate echocardiographic parameters, especially the Tei index as a predictor of outcome in critically ill children on continuous renal...
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Non-invasive assessment of HFpEF in mouse models: current gaps and future directions
BackgroundHeart failure (HF) with preserved ejection fraction (HFpEF) prevalence is increasing, and large clinical trials have failed to reduce...
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Clinical and echocardiography predictors of response to first-line acetaminophen treatment in preterm infants with hemodynamically significant patent ductus arteriosus
ObjectiveTo assess clinical and echocardiography predictors of acetaminophen response for the treatment of patent ductus arteriosus (PDA) in preterm...