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Evidence that complement and coagulation proteins are mediating the clinical response to omega-3 fatty acids: A mass spectrometry-based investigation in subjects at clinical high-risk for psychosis
Preliminary evidence indicates beneficial effects of omega-3 polyunsaturated fatty acids (PUFAs) in early psychosis. The present study investigates...
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Prognostic value of laboratory markers in patients with acute pulmonary embolism
BackgroundAcute pulmonary embolism (APE) is a serious illness. Identifying prognostic factors for APE may help in the management of those patients....
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Markers of Endothelial Dysfunction in Kawasaki Disease: An Update
Kawasaki disease (KD) is a medium vessel vasculitis that has a special predilection for coronary arteries. Cardiovascular complications include the...
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Plasma proteomics associated with autoimmune coagulation factor deficiencies reveals the link between inflammation and autoantibody development
Autoimmune coagulation factor deficiency (AiCFD) is characterized by sudden excessive bleeding due to autoantibodies against coagulation factors....
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Systemic coagulation is activated in patients with meningioma and glioblastoma
PurposeUp to 30% of patients with glioblastoma (GBM) develop venous thromboembolism (VTE) over the course of the disease. Although not as high, the...
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Global coagulation assays in healthy controls: are there compensatory mechanisms within the coagulation system?
Global coagulation assays (GCAs) may provide a more comprehensive individual hemostatic profiling. We aim to evaluate GCAs (thromboelastography,...
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Sepsis-related coagulopathy treatment based on the disseminated intravascular coagulation diagnostic criteria: a post-hoc analysis of a prospective multicenter observational study
BackgroundThe development of disseminated intravascular coagulation (DIC) in patients with sepsis has been repeatedly confirmed as a factor...
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Serum liver fibrosis markers predict hepatic decompensation in compensated cirrhosis
Background and aimThe literature is sparse on the association between serum liver fibrosis markers and the development of hepatic decompensation in...
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The change of coagulation profile in two-staged arthroplasty for periprosthetic joint infection patients: a retrospective cohort study
AimsPeriprosthetic joint infection (PJI) is a serious complication of total joint arthroplasty. We performed a retrospective cohort study to evaluate...
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Impact of inflammation and steroids on anti-coagulation in children supported on a ventricular assist device
Critically ill pediatric patients supported on ventricular assist devices (VADs) are increasingly being anticoagulated on bivalirudin, but with...
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Comprehensive coagulation and fibrinolytic potential in the acute phase of pediatric patients with idiopathic nephrotic syndrome evaluated by whole blood-based rotational thromboelastometry
BackgroundVenous thromboembolism is a rare, serious complication of idiopathic nephrotic syndrome (INS) in childhood. The mechanisms responsible for...
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Key Drivers of Coagulation Factor Use in Von Willebrand Disease During Hospitalization: An Overview of the French BERHLINGO Cohort
BackgroundVon Willebrand disease (VWD) is the most common inherited bleeding disorder. However, studies of hospitalisation patterns with replacement...
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Brain MRI imaging markers associated with death in children with central nervous system involvement of hemophagocytic lymphohistiocytosis
ObjectivesTo investigate the association of brain MRI and clinical variables with death in children with central nervous system involvement of...
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COVID-19-associated coagulopathy and disseminated intravascular coagulation
The pathology of coronavirus disease 2019 (COVID-19) is exacerbated by the progression of thrombosis, and disseminated intravascular coagulation...
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Changes in platelet count and coagulation parameters in children with obstructive sleep apnea
ObjectiveTo investigate the correlation between obstructive sleep apnea (OSA) and coagulation status and to speculate on the underlying mechanism in...
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Changes and significance of vascular endothelial injury markers in patients with diabetes mellitus and pulmonary thromboembolism
BackgroundTo investigate the changes and clinical significance of vascular endothelial injury markers in type 2 diabetes mellitus (T2DM) complicated...
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Potential utility of a multi-component coagulation factor panel to calculate MELD scores and assess the risk of portal vein thrombosis in chronic liver disease
BackgroundCurrent quantitative approaches to assess chronic liver disease (CLD) severity have limitations. Further, portal vein thrombosis (PVT)...
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Associations between inflammation, coagulation, cardiac strain and injury, and subclinical vascular disease with frailty in older men: a cross-sectional study
BackgroundInflammation, coagulation activation, endothelial dysfunction and subclinical vascular disease are cross-sectionally associated with...
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Thromboelastography-Based Profiling of Coagulation Status in Patients Undergoing Bariatric Surgery: Analysis of 422 Patients
Introduction/PurposeSome clinical indicators suggest hypercoagulability/hyperaggregability in patients with morbid obesity. Thromboelastography...
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Markers of Venous Thromboembolism Risk in Patients with Alopecia Areata: Is There Anything to Worry about?
BackgroundNumerous studies have indicated that alopecia areata is associated with a chronic systemic inflammation, which is considered as a risk...