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Early diagnosis and prognostic potential of RAC3 in bladder tumor
Background and purposeBladder tumors are among the most prevalent malignancies in the urinary system, and RAC3 has been linked to various types of...
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A Rare Case of Calvaria Solitary Fibrous Tumor: Case Report and Review of Literature
A rare case of primary osseous solitary fibrous tumor (SFT) located in the calvaria is described. SFTs, previously called hemangiopericytomas (HPC),...
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Immunological subty** of salivary gland cancer identifies histological origin-specific tumor immune microenvironment
Gene expression analysis enhances proper cancer subty**, a better understanding of the molecular characteristics of cancer, and strategies for...
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COL5A1 promotes triple-negative breast cancer progression by activating tumor cell-macrophage crosstalk
Triple-negative breast cancer (TNBC) is an exceptionally aggressive subtype of breast cancer. Despite the recognized interplay between tumors and...
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Gastric tumor mimicking bronchial tissue associated with a laryngotracheoesophageal cleft: a case report
BackgroundLaryngotracheoesophageal cleft (LTEC) is a rare disease in which the larynx and trachea communicate posteriorly to the esophagus. It is...
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Relationship of FDG PET/CT imaging features with tumor immune microenvironment and prognosis in colorectal cancer: a retrospective study
BackgroundImaging features of colorectal cancers on 2-deoxy-2-[ 18 F]fluoro-d-glucose (FDG) positron emission tomography/computed tomography (PET/CT)...
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Primary hyperparathyroidism presenting as a brown tumor in the mandible: a case report
BackgroundPrimary hyperparathyroidism is characterized by hypercalcemia and elevated or inappropriately normal serum levels of parathyroid hormone....
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M2-type tumor-associated macrophages upregulated PD-L1 expression in cervical cancer via the PI3K/AKT pathway
Background and purposePD-1/PD-L1 inhibitors have become a promising therapy. However, the response rate is lower than 30% in patients with cervical...
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Renal inflammatory myofibroblastic tumor coexisting with hemophilia A carrier: a case report and literature review
Renal inflammatory myofibroblastic tumor (IMT) is an exceptionally uncommon occurrence. This report presented the first documented case of renal IMT...
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Oral granular cell tumor: a collaborative clinicopathological study of 61 cases
BackgroundGranular Cell Tumor (GCT) is an uncommon benign lesion in the oral cavity whose pathogenesis remains poorly understood. Due to their...
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Successful resection of a hypervascular paravertebral solitary fibrous tumor of pleura preserving the artery of Adamkiewicz, which was detected on preoperative angiography
BackgroundSolitary fibrous tumor of the pleura is rarely observed, accounting for 1% of all mediastinum tumors. There have been only a few reports of...
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Oxygen supplementation in anesthesia can block FLASH effect and anti-tumor immunity in conventional proton therapy
BackgroundRadiation-induced neurocognitive dysfunction is a major adverse effect of brain radiation therapy and has specific relevance in pediatric...
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Combination of STING agonist with anti-vascular RGD-(KLAKLAK)2 peptide as a novel anti-tumor therapy
Immunotherapy is one of the most promising anti-cancer treatment. It involves activating the host's own immune system to eliminate cancer cells....
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Atypical presentation of polymorphous low-grade neuroepithelial tumor of young (PLNTY): a case report
The polymorphous low-grade neuroepithelial tumor of young (PLNTY) is considered as one among the low-grade neuroepithelial tumor; as per WHO-2021...
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Identification of tumor antigens and immune subtypes of acute myeloid leukemia for mRNA vaccine development
BackgroundAcute myeloid leukemia (AML) is a highly aggressive hematological malignancy, and there has not been any significant improvement in therapy...
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Integrative lactylation and tumor microenvironment signature as prognostic and therapeutic biomarkers in skin cutaneous melanoma
BackgroundThe incidence of skin cutaneous melanoma (SKCM), one of the most aggressive and lethal skin tumors, is increasing worldwide. However, for...
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Highly Expressed Z-DNA Binding Protein 1 in Esophageal Cancer Promotes Tumor Growth
BackgroundEsophageal cancer (ESCA) is a common malignant tumor of the digestive tract, and its poor prognosis is mainly attributed to the occurrence...
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TMPRSS2 is a tumor suppressor and its downregulation promotes antitumor immunity and immunotherapy response in lung adenocarcinoma
BackgroundTMPRSS2, a key molecule for SARS-CoV-2 invading human host cells, has an association with cancer. However, its association with lung cancer...
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Expression of tumor-associated macrophages and PD-L1 in patients with hepatocellular carcinoma and construction of a prognostic model
BackgroundHepatocellular carcinoma (HCC) is an inflammation-associated tumor involved in immune tolerance and evasion in the immune microenvironment....
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Germ Cell Tumor Presenting as a Mesenteric Cyst: a Case Report and Literature Review
Mesenteric cysts, typically benign and asymptomatic, are incidental findings during abdominal investigations for nonspecific symptoms. Their origin...
