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Impact of frailty on the outcomes of patients undergoing degenerative spine surgery: a systematic review and meta-analysis
BackgroundDegenerative spinal diseases are common in older adults with concurrent frailty. Preoperative frailty is a strong predictor of adverse...
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Home-Based Exercise Programs for the Oldest-Old to Attenuate Physical Frailty: A Sco** Review
BackgroundWith the significant increase in the number of long-lived elderly people living at home, the development of effective physical exercise...
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Low-Income Older Adults’ Vulnerability to Anticholinergic Medication-Associated Frailty
BackgroundA growing body of research supports the negative impact of anticholinergic drug burden on physical frailty. However, prior research has...
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Frailty and its association with health-related quality of life among older cancer patients: an evidence-based study from China
BackgroundThere is limited information about the population characteristics and adverse health outcomes of older cancer patients in China. This study...
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Frailty assessment to individualize treatment in older patients with lymphoma
PurposeA study analyzing the application of a protocol of comprehensive geriatric assessment (CGA) in older patients with lymphoma was carried out to...
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Myokines and Biomarkers of Frailty in Older Inpatients with Undernutrition: A Prospective Study
BackgroundPopulation aging might increase the prevalence of undernutrition in older people, which increases the risk of frailty. Numerous studies...
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Number of Teeth and Denture Use Are Associated with Frailty among Chinese Older Adults: A Cohort Study Based on the CLHLS from 2008 to 2018
ObjectivesThe aim of this study was to determine the association between oral health and the development of frailty over a 10-year period in older...
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Cellular Senescence and Frailty in Transplantation
Purpose of ReviewTo summarize the literature on cellular senescence and frailty in solid-organ transplantation and highlight the emerging role of...
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Relationship between oral frailty, health-related quality of life, and survival among long-term care residents
PurposeWe evaluated oral frailty (OFr) and its association with health-related quality of life (HRQoL), energy and protein intake, and survival among...
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Identifying Frailty in Administrative Databases: A Narrative Review
Frailty is a state of increased vulnerability that can lead to premature death. While various clinical tools effectively measure frailty in...
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Lower serum creatinine to cystatin C ratio associated with increased incidence of frailty in community-dwelling elderly men but not in elderly women
BackgroundSarcopenia has been reported to play an important role in frailty syndrome. The serum creatinine/serum cystatin C ratio (Scr/Cys C ratio)...
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What role do extracellular vesicles play in develo** physical frailty and sarcopenia?
BackgroundFrailty and sarcopenia are typical geriatric conditions with a complex pathophysiology. Extracellular vesicles (EVs) are key regulators of...
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A comparison between the clinical frailty scale and the hospital frailty risk score to risk stratify older people with emergency care needs
BackgroundOlder adults living with frailty who require treatment in hospitals are increasingly seen in the Emergency Departments (EDs). One quick and...
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Exploring the metabolomics profile of frailty- a systematic review
BackgroundFrailty is a multifaceted geriatric syndrome characterized by an increased vulnerability to stressful events. metabolomics studies are...
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Frailty Assessed by the Clinical Frailty Scale is Associated with Prognosis After Esophagectomy
BackgroundThe Clinical Frailty Scale (CFS) is a simple and validated tool for assessing frailty, and higher CFS scores are correlated with worse...
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Nocturia and frailty in older adults: a sco** review
BackgroundMore than one in two older people wake up several times a night to urinate. Far from being a minor inconvenience, nocturia is associated...
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Association between Frailty Assessed Using Two Electronic Medical Record-Based Frailty Assessment Tools and Long-Term Adverse Prognosis in Older Critically Ill Survivors
ObjectivesFrailty has become an independent risk factor for adverse outcomes in critically ill patients. This study aimed to explore the predictive...
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Frailty in Chile: Development of a Frailty Index Score Using the Chilean National Health Survey 2016–2017
BackgroundThe Frailty Index (FI) is used to quantify and summarize vulnerability status in people. In Chile, no development and assessment of a FI...
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Symptomatic and preventive medication use according to age and frailty in Australian and Japanese nursing homes
ObjectiveTo investigate symptomatic and preventive medication use according to age and frailty in Australian and Japanese nursing homes (NHs).
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Falls, fracture and frailty risk in multiple sclerosis: a Mendelian Randomization study to identify shared genetics
IntroductionPatients with multiple sclerosis (MS) commonly present musculoskeletal disorders characterized by lower bone mineral density (BMD) and...
