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Pathological study of the 2019 novel coronavirus disease (COVID-19) through postmortem core biopsies
Data on pathologic changes of the 2019 novel coronavirus disease (COVID-19) are scarce. To gain knowledge about the pathology that may contribute to...
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Rapidly progressive interstitial lung disease in patients with anti-melanoma differentiation-associated gene 5-positive dermatomyositis: serial changes on HRCT
BackgroundAnti-melanoma differentiation-associated gene 5 (anti-MDA5) antibodies in patients with dermatomyositis are associated with rapidly...
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G6PD deficiency—does it alter the course of COVID-19 infections?
Despite the existence of well-founded data around the relationship between reactive oxygen species (ROS) and glucose-6-phosphate dehydrogenase...
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The pathogenic role of epithelial and endothelial cells in early-phase COVID-19 pneumonia: victims and partners in crime
Current understanding of the complex pathogenesis of COVID-19 interstitial pneumonia pathogenesis in the light of biopsies carried out in...
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The relationship between lung fibrosis, the epidermal growth factor receptor, and disease outcomes in COVID-19 pneumonia: a postmortem evaluation
The aim of this study was to examine the relationship between the severity of fibrosis in lung tissue and epidermal growth factor receptor (EGFR)...
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Beta-containing bivalent SARS-CoV-2 protein vaccine elicits durable broad neutralization in macaques and protection in hamsters
BackgroundSince the beginning of the COVID-19 pandemic, several variants of concern (VOC) have emerged for which there is evidence of an increase in...
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Predelivery HbA1c levels and their relationship with adverse perinatal outcomes in women with normal 75-g OGTT
PurposeTo analyze the elevation of HbA1c before full-term delivery in single pregnancy with normal 75 g- Oral glucose tolerance test (OGTT) screening...
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Radioprotective effects of gliclazide against irradiation-induced cardiotoxicity and lung injury through inhibiting oxidative stress
Radiotherapy is one of the main treatments for localized primary cancer in patients. Cardiotoxicity and lung injury are two of the main side effects...
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Pathophysiology of SARS-CoV-2: the Mount Sinai COVID-19 autopsy experience
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated clinical syndrome COVID-19 are causing overwhelming morbidity and...
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Late pulmonary complications related to cancer treatment in children
As the number of childhood cancer survivors increases, a heightened awareness and recognition of therapy-related late effects is becoming more...
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Bystander CD8 + T cells may be involved in the acute phase of diffuse alveolar damage
Acute respiratory distress syndrome (ARDS) is a serious complication of systemic inflammatory response syndrome, and diffuse alveolar damage (DAD) is...
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Connective tissue disease-associated lung disease in children
Connective tissue diseases are a heterogeneous group of autoimmune diseases that can affect a variety of organ systems. Lung parenchymal involvement...
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Pulmonary sclerosing pneumocytoma—a case series
Pulmonary sclerosing pneumocytoma (PSP) is a rare and interesting pulmonary tumour that presents a diagnostic challenge to the surgeon due to its...
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A large deletion encompassing exon 2 of the ectodysplasin A (EDA) gene in a British blue crossbred calf with hypohidrotic ectodermal dysplasia
BackgroundHypohidrotic ectodermal dysplasia (HED) is a congenital syndrome of mammals affecting organs and tissues of ectodermal origin characterized...
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Pulmonary sclerosing pneumocytoma: clinical features and prognosis
BackgroundPulmonary sclerosing pneumocytoma is a kind of rare benign pulmonary tumor with potential malignancy. The clinical features, risk factors...
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Fibrotic progression and radiologic correlation in matched lung samples from COVID-19 post-mortems
Data on the pathology of COVID-19 are scarce; available studies show diffuse alveolar damage; however, there is scarce information on the chronologic...
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Potential biomarkers used for risk estimation of pediatric sepsis-associated organ dysfunction and immune dysregulation
AbstractPediatric sepsis is a serious issue globally and is a significant cause of illness and death among infants and children. Refractory septic...
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Proposal of a grading system for squamous cell carcinoma of the lung — the prognostic importance of tumour budding, single cell invasion, and nuclear diameter
The prognostic markers of lung squamous cell carcinoma (LSCC) are less investigated. The aim of our study was to evaluate tumour budding (TB),...
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Machine learning model identifies aggressive acute pancreatitis within 48 h of admission: a large retrospective study
BackgroundAcute pancreatitis (AP) with critical illness is linked to increased morbidity and mortality. Current risk scores to identify high-risk AP...
