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MRI feature-based radiomics models to predict treatment outcome after stereotactic body radiotherapy for spinal metastases
ObjectiveThis study aimed to extract radiomics features from MRI using machine learning (ML) algorithms and integrate them with clinical features to...
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Conditional survival after surgery for metastatic tumors of the spine: does prognosis change over time?
PurposeConditional survival (CS) provides a dynamic prediction of patient survival by incorporating the time an individual has already survived given...
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En-bloc spondylectomy in the lumbar spine: indications, results and complications in a series of 47 patients affected by primary malignant bone tumors
IntroductionWide Surgery is the reference treatment for malignant and aggressive benign primary bone tumors in the spine. When located in the lumbar...
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Palliative Arterial Embolization for Metastases of the Sternum
BackgroundTo investigate the safety and efficacy of palliative arterial embolization for metastases of the sternum.
Materials and Methods ...
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Computed tomography density changes of bone metastases after concomitant denosumab
ObjectiveTo evaluate bone density changes at the level of normal trabecular bone and bone metastases (BMs) after denosumab (DM) treatment in...
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Biodistribution and dosimetry of 177Lu-DOTA-IBA for therapy of bone metastases
BackgroundWe designed and synthesized a novel bisphosphonate radiopharmaceutical ( 68 Ga- or 177 Lu-labeled DOTA-ibandronate [ 68 Ga/ 177 Lu-DOTA-IBA])...
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Frailty indices in patients undergoing surgical resection of brain metastases: a systematic review
Brain metastases are a relatively common occurrence in patients with primary malignancies, with an incidence ranging from 9 to 17%. Their prevalence...
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Modified percutaneous biopsy of the spine: improvement of the technique
PurposeBiopsy of the spine can be performed by open surgery or percutaneous needle sampling. The first has the highest diagnostic yield while the...
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The application of 3D-printed auto-stable artificial vertebral body in en bloc resection and reconstruction of thoracolumbar metastases
BackgroundNerve compression symptoms and spinal instability, resulting from spinal metastases, significantly impact the quality of life for patients....
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Pancreatic Cancer Metastases to a Klippel-Feil Congenital Fusion of the Cervical Spine: Case Report
To our knowledge, metastasis to the site of congenital cervical fusion in Klippel-Feil syndrome (KFS) has not been described before and this report...
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Combining morphological and functional imaging parameters to diagnose primary bone neoplasms in the skull base, spine and sacrum
PurposeMorphological magnetic resonance (MR) and computed tomography (CT) features are used in combination with histology for diagnosis and treatment...
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Assessing visibility and bone changes of spinal metastases in CT scans: a comprehensive analysis across diverse cancer types
ObjectivesTo analyze the characteristics of spinal metastasis in CT scans across diverse cancers for effective diagnosis and treatment, using MRI as...
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Whole-body MRI: detecting bone metastases from prostate cancer
Whole-body magnetic resonance imaging (WB-MRI) is currently used worldwide for detecting bone metastases from prostate cancer. The 5-year survival...
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Validating the screening criteria for bone metastases in treatment-naïve unfavorable intermediate and high-risk prostate cancer - the prevalence and location of bone- and lymph node metastases
ObjectiveThe European Association of Urology (EAU) recommends a bone scan for newly diagnosed unfavorable intermediate- and high-risk prostate...
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The efficacy of laser interstitial thermal therapy in the management of spinal metastases: a systematic review of the literature
BackgroundIn the last years, laser interstitial thermal therapy (LITT) has started to be used also in neurosurgical setting. Its efficacy for...
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Aggressive variant prostate cancer with multiple subcutaneous metastases: a case report
A 71-year-old man with bone metastasis of hormone-sensitive prostate cancer was treated with androgen deprivation therapy and apalutamide. Radium-223...
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Design and 3D printing of novel titanium spine rods with lower flexural modulus and stiffness profile with optimised imaging compatibility
PurposeTo manufacture and test 3D printed novel design titanium spine rods with lower flexural modulus and stiffness compared to standard solid...
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Clinical efficacy analysis of percutaneous “tripod” combined with radiofrequency ablation and bone cement filling in the treatment of periacetabular metastases
BackgroundTo investigate the clinical efficacy of a percutaneous “tripod” combined with radiofrequency ablation and bone cement filling surgery in...
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Radiomics analysis based on CT for the prediction of pulmonary metastases in ewing sarcoma
ObjectivesThis study aimed to develop and validate radiomics models on the basis of computed tomography (CT) and clinical features for the prediction...
