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Organotrifluoroborate enhances tumor targeting of fibroblast activation protein inhibitors for targeted radionuclide therapy
PurposeFibroblast activation protein (FAP) is a pan-cancer target and now the state-of-the-art to develop radiopharmaceuticals. FAP inhibitors have...
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Locoregional Radionuclide Cancer Therapy Clinical and Scientific Aspects
This book reviews locoregional radionuclide cancer therapies (LRCT). Proving an increasingly viable alternative to radiotherapy, radionuclide therapy...
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Routine first-line detection of breast cancer therapy-related cardiotoxicity by serial, fast and ultra-low-dose equilibrium radionuclide angiography
BackgroundThis study assesses a first-line left ventricular ejection fraction (LVEF) monitoring provided by an ultra-low-dose equilibrium...
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Preclinical evaluation of FAP-2286 for fibroblast activation protein targeted radionuclide imaging and therapy
PurposeFibroblast activation protein (FAP) is a membrane-bound protease that has limited expression in normal adult tissues but is highly expressed...
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Radionuclide Imaging of Infection and Inflammation A Pictorial Case-Based Atlas
This atlas explores the latest advances in radionuclide imaging in the field of inflammatory diseases and infections, which now typically includes... -
EANM recommendations based on systematic analysis of small animal radionuclide imaging in inflammatory musculoskeletal diseases
Inflammatory musculoskeletal diseases represent a group of chronic and disabling conditions that evolve from a complex interplay between genetic and...
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Efficacy and safety of peptide receptor radionuclide therapy with [177Lu]Lu-DOTA-TATE in 15 patients with progressive treatment-refractory meningioma
PurposeThere is no evidence-based systemic therapy for patients with progressive meningiomas for whom surgery or external radiotherapy is no longer...
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Semi-automated segmentation methods of SSTR PET for dosimetry prediction in refractory meningioma patients treated by SSTR-targeted peptide receptor radionuclide therapy
ObjectivesTumor dosimetry with somatostatin receptor–targeted peptide receptor radionuclide therapy (SSTR-targeted PRRT) by 177 Lu-DOTATATE may...
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First preclinical evaluation of [225Ac]Ac-DOTA-JR11 and comparison with [177Lu]Lu-DOTA-JR11, alpha versus beta radionuclide therapy of NETs
BackgroundThe [ 177 Lu]Lu-DOTA-TATE mediated peptide receptor radionuclide therapy (PRRT) of neuroendocrine tumors (NETs) is sometimes leading to...
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Peptide Receptor Radionuclide Therapy of Pulmonary Neuroendocrine Neoplasms: a Single-Centre Experience
PurposePeptide receptor radionuclide therapy represents a therapeutic option for neuroendocrine neoplasms; to date, experiences with peptide receptor...
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Dosimetry in Lu-177-DOTATATE peptide receptor radionuclide therapy: a systematic review
Purpose177 Lu- labelled somatostatin analog DOTATATE is an excellent vector for systemic radiation therapy in NETs. However, this treatment can...
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In patients with well-differentiated neuroendocrine tumours, there is no apparent benefit of somatostatin analogues after disease control by peptide receptor radionuclide therapy
PurposePeptide receptor radionuclide therapy (PRRT) and somatostatin analogues (SSAs) are commonly combined as primary treatment for neuroendocrine...
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In vitro and in vivo study on the treatment of non-small cell lung cancer with radionuclide labeled PD-L1 nanobody
PurposeNanobodies have become promising carriers due to excellent in vivo properties. Radiopharmaceutical therapy targeting programmed cell death...
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Strategies Towards Improving Clinical Outcomes of Peptide Receptor Radionuclide Therapy
Purpose of ReviewPeptide receptor radionuclide therapy (PRRT) with [ 177 Lu-DOTA 0 ,Tyr 3 ] octreotate is an effective and safe second- or third-line...
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ASNC Imaging Indications (ASNC-I2): Multisocietal indications for radionuclide imaging in the multimodality context—Series rationale and methodology
BackgroundAppropriate use criteria (AUC) enhance application of cardiovascular imaging techniques but have been applied in limited settings,...
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Prostate-Specific Membrane Antigen (PSMA)-Targeted Radionuclide Therapies for Prostate Cancer
Purpose of ReviewProstate-specific membrane antigen (PSMA)-targeted radionuclide therapy (TRT) is a promising investigational treatment for...