Search
Search Results
-
Cardiovascular safety of using non-steroidal anti-inflammatory drugs for gout: a Danish nationwide case-crossover study
Gout attacks are treated with uric-lowering and anti-inflammatory drugs. In patients with gout, non-steroidal anti-inflammatory drugs (NSAIDs) could...
-
The effect of exercise rehabilitation with exergames combined with ice therapy in the treatment of obese patients with gout: protocol for a clinical trial
BackgroundGout remains a leading cause of inflammatory arthritis worldwide, and the main risk factor for gout is persistent hyperuricemia. The...
-
Coffee intake reduced gout risk by decreasing urate and urea while increasing SHBG levels in plasma: a mediation Mendelian randomization study
ObjectiveThis study aims to investigate the causal relationships between specific dietary habits and the risk of gout, while identifying the...
-
Metabolomic analysis for asymptomatic hyperuricemia and gout based on a combination of dried blood spot sampling and mass spectrometry technology
BackgroundGout is the most common inflammatory arthritis and closely related to metabolic syndrome, leading to excruciating pain and the decline in...
-
Circulating microRNA alternations in primary hyperuricemia and gout
ObjectivesMicroRNAs (miRNAs) are short single-stranded RNAs that play a role in the post-transcriptional regulation of gene expression. Their...
-
Egyptian consensus on treat-to-target approach of gout: evidence-based clinical practice guidelines for the management of gout
IntroductionNew therapies, management approaches, and evidence regarding the management of gout have become available over the past years. This...
-
Gender differences in illness perceptions and disease management in patients with gout, results from a questionnaire study in Western Sweden
BackgroundAims were to examine gender differences in patients with gout with regard to a) self-reported gout severity, b) illness perceptions (IP),...
-
Prevalence of Diabetes in Patients with Hyperuricemia and Gout: A Systematic Review and Meta-analysis
Purpose of ReviewTo perform a systematic review and meta-analysis of the prevalence of diabetes in patients with hyperuricemia and gout.
...
-
Relationship between gout, hyperuricemia, and obesity—does central obesity play a significant role?—a study based on the NHANES database
BackgroundOur objective was to evaluate how various measures of obesity, such as body mass index(BMI), body roundness index(BRI), and weigh adjusted...
-
Gut microbiota mediated the therapeutic efficiency of Simiao decoction in the treatment of gout arthritis mice
BackgroundGut microbiota plays a significant role in the development and treatment of gouty arthritis. Simiao decoction has been shown to alleviate...
-
Critical appraisal of serum urate targets in the management of gout
Gout management involves two broad aspects: treatment of gout flares to provide rapid symptomatic relief and long-term urate-lowering therapy to...
-
Effect of omega-three supplementation on serum urate and gout flares in people with gout; a pilot randomized trial
ObjectivesTo determine the effect of omega-three supplementation with fish oil on serum urate, weight and body mass index (BMI) in people with gout.
...
-
SToRytelliing to Improve Disease outcomes in Gout (STRIDE-GO) in African American veterans with gout: a trial study protocol
ObjectiveMedication adherence in gout is suboptimal, and the lack of effective interventions to address it presents a huge challenge. Medication...
-
Prevalence of motor neuron diseases in gout patients: a nationwide population-based cohort study
BackgroundIncreased uric acid may have a protective effect in motor neuron diseases (MNDs). The association between gout, characterized by...
-
SToRytelling to Improve Disease outcomes in Gout (STRIDE-GO): a multicenter, randomized controlled trial in African American veterans with gout
BackgroundUrate-lowering therapy (ULT) adherence is low in gout, and few, if any, effective, low-cost, interventions are available. Our objective was...
-
Insulin use and gout risk among patients with type 2 diabetes mellitus: a real-world cohort study in Shanghai, China
ObjectivesThe effect of insulin use on gout risk remains unknown. This study aimed to investigate the association between insulin use and gout risk...
-
The risk of nonalcoholic fatty liver disease in gout patients with frequent flares: a retrospective cohort study
ObjectiveNonalcoholic fatty liver disease (NAFLD) is a common chronic disease that is related to high serum uric acid; however, the association...
-
Differential gene expression of ABCG2, SLC22A12, IL-1β, and ALPK1 in peripheral blood leukocytes of primary gout patients with hyperuricemia and their comorbidities: a case–control study
BackgroundThe ABCG2, SLC22A12, and ALPK1 genes have been strongly associated with dysfunction of urate metabolism in patients with gout, but it is...
-
What are the core recommendations for gout management in first line and specialist care? Systematic review of clinical practice guidelines
BackgroundGout is the most common inflammatory arthritis, increasing in prevalence and burden. Of the rheumatic diseases, gout is the best-understood...
-
Comparison of the efficacy and safety of benzbromarone and febuxostat in gout and hyperuricemia: a systematic review and meta-analysis
ObjectiveUrate-lowering therapy (ULT) is widely recognized as the primary treatment for hyperuricemia and gout. Xanthine oxidase inhibitors (XOI),...
