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Intraoperative motor-evoked potential with tetanic stimulation changes pre- and post-hemispherotomy
BackgroundCareful examination of motor-evoked potential (MEP) findings is critical to the safety of intraoperative neuromonitoring during...
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Acquired resistance to osimertinib in patients with non-small-cell lung cancer: mechanisms and clinical outcomes
PurposeOsimertinib, a third-generation epidermal growth factor receptor tyrosine-kinase inhibitor (EGFR-TKI), has demonstrated substantial clinical...
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MYCN amplification, TERT rearrangements and ATRX mutations in neuroblastoma: clinicopathological correlates- an Indian perspective
BackgroundNeuroblastoma (NB) is the most common extracranial solid tumour in childhood with a diverse clinical presentation and course. The early age...
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Development of a CRISPR/Cas12a-based fluorescent detection method of Senecavirus A
BackgroundSenecavirus A (SVA), identified in 2002, is known to cause porcine idiopathic vesicular disease (PIVD), which presents with symptoms...
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Reducing travel-related SARS-CoV-2 transmission with layered mitigation measures: symptom monitoring, quarantine, and testing
BackgroundBalancing the control of SARS-CoV-2 transmission with the resumption of travel is a global priority. Current recommendations include...
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Extraskeletal chondroma of the toe in a child with DICER1 tumor predisposition syndrome: support for a dominant negative mechanism
DICER1 tumor predisposition syndrome is a pleiotropic disorder that gives rise to various mainly pediatric-onset lesions. We report an extraskeletal...
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The Origin Along the Cochlea of Otoacoustic Emissions Evoked by Mid-Frequency Tone Pips
PurposeTone-pip-evoked otoacoustic emissions (PEOAEs) are transient-evoked otoacoustic emissions (OAEs) that are hypothesized to originate from...
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Optimisation of the DNA dipstick as a rapid extraction method for Schistosoma japonicum in infected mice samples and spiked human clinical samples
BackgroundSchistosomiasis remains a public health issue and the need for accurate and affordable diagnostics is crucial in the elimination of the...
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Molecular and phenotypic identification of bacterial species isolated from cows with mastitis from three regions of Poland
BackgroundBovine mastitis is a widespread disease affecting dairy cattle worldwide and it generates substantial losses for dairy farmers. Mastitis...
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Primary Epithelioid Angiosarcoma of the Submandibular Gland—A Case Report with Histology-Cytology Correlation and Comprehensive Molecular Analysis
BackgroundAngiosarcoma is a sarcoma that occurs in a range of tissue types, and only rarely in the salivary glands, showing a predilection for the...
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Detection method for reverse transcription recombinase-aided amplification of avian influenza virus subtypes H5, H7, and H9
BackgroundAvian influenza virus (AIV) not only causes huge economic losses to the poultry industry, but also threatens human health. Reverse...
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Serological investigation and isolation of Salmonella abortus equi in horses in **njiang
BackgroundSalmonella enterica subspecies enterica serovar abortus equi ( S. abortus equi ) is one of the main pathogens that causes abortion in...
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A Reliable Method for Quantifying Plasma Cell-Free DNA Using an Internal Standard Strategy: Evaluation in a Cohort of Non-Pregnant and Pregnant Women
The use of plasma cell-free DNA (cfDNA) as a useful biomarker in obstetric clinical practice has been delayed due to the lack of reliable...
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Specific quantification of inducible HIV-1 reservoir by RT-LAMP
BackgroundStrategies toward HIV-1 cure aim to clear, inactivate, reduce, or immunologically control the virus from a pool of latently infected cells...
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Central nervous system embryonal tumor with PLAGL1 amplification: a case report of a novel entity focusing on imaging findings
The embryonal central nervous system (CNS) tumor with PLAGL1 (pleomorphic adenoma gene-like) amplification is a novel type of pediatric neoplasm with...
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The value of GLI1 and p16 immunohistochemistry in the premolecular screening for GLI1-altered mesenchymal neoplasms
Mesenchymal neoplasms with GLI1 alterations have recently been reported in several anatomic locations. Their morphology and immunohistochemistry...
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Clinical application of the HM-1000 image processing for HER2 fluorescence in situ hybridization signal quantification in breast cancer
BackgroundAccurate quantification of human epidermal growth factor receptor 2 ( HER2 ) gene amplification is important for predicting treatment...
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Blocker displacement amplification-based genetic diagnosis for autosomal dominant polycystic kidney disease and the clinical outcomes of preimplantation genetic testing
ObjectiveGiven that the molecular diagnosis of autosomal dominant polycystic kidney disease (ADPKD) is complicated, we aim to apply blocker...
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A phase I trial of the pan-ERBB inhibitor neratinib combined with the MEK inhibitor trametinib in patients with advanced cancer with EGFR mutation/amplification, HER2 mutation/amplification, HER3/4 mutation or KRAS mutation
PurposeAberrant alterations of ERBB receptor tyrosine kinases lead to tumorigenesis. Single agent therapy targeting EGFR or HER2 has shown clinical...
