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Lower anatomical femoral ACL tunnel can be created in the large volume of femoral intercondylar notch
PurposeThe purpose of this study was to investigate the correlation between femoral intercondylar notch volume and the characteristics of femoral...
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2nd Window NIR Imaging of Radiation Injury Mitigation Provided by Reduced Notch-Dll4 Expression on Vasculature
PurposeVascular endothelium plays a central role in the pathogenesis of acute and chronic radiation injuries, yet the mechanisms which promote...
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Sex-specific involvement of the Notch–JAG pathway in social recognition
Under the hypothesis that olfactory neural epithelium gene expression profiles may be useful to look for disease-relevant neuronal signatures, we...
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Age-related prevalence and imaging characteristics of the superior acetabular roof notch in children, adolescents, and young adults
ObjectiveTo determine the age-related prevalence and imaging characteristics of the superior acetabular roof notch (SARN) on hip MRI and radiographs...
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Automatic segmentation model of intercondylar fossa based on deep learning: a novel and effective assessment method for the notch volume
BackgroundNotch volume is associated with anterior cruciate ligament (ACL) injury. Manual tracking of intercondylar notch on MR images is...
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The lateral femoral notch sign and coronal lateral collateral ligament sign in magnetic resonance imaging failed to predict dynamic anterior tibial laxity
PurposeTo investigate the relationship between the lateral femoral notch sign as well as the coronal lateral collateral ligament (LCL) sign and...
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The influence of age on greater sciatic notch morphology: testing the Walker method in an Australian population
Sex estimation is an integral aspect of a forensic biological profile. The pelvis, being the most dimorphic part of the skeleton, has been studied in...
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Study of Strawberry Notch homolog 1 and 2 expression in human glioblastoma
PurposeIn this work, we aimed to comprehensively document the expression of Strawberry Notch homolog (SBNO) 1 and 2 in glioblastoma (GBM) tissue and...
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NOTCH gene alterations in metastatic colorectal cancer in the Nationwide Cancer Genome Screening Project in Japan (SCRUM-Japan GI-SCREEN)
PurposeActivated Notch receptor signaling has been implicated in tumor growth and progression in colorectal cancer (CRC). However, the pathogenic...
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Mammary Development and Breast Cancer: a Notch Perspective
Mammary gland development primarily occurs postnatally, and this unique process is complex and regulated by systemic hormones and local growth...
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Posterior tibial slope, notch width index and tibial tubercle to trochlear groove distance contribute to development of mucoid degeneration of the anterior cruciate ligament: a systematic review
PurposeTo determine what knee morphological factors are associated with the development of mucoid degeneration of the anterior cruciate ligament...
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Roles of the Notch Signaling Pathway in Ovarian Functioning
The Notch signaling pathway regulates cell invasion, adhesion, proliferation, apoptosis, and differentiation via cell-to-cell interactions and plays...
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CircFBXW7 in patients with T-cell ALL: depletion sustains MYC and NOTCH activation and leukemia cell viability
Circular RNAs (circRNAs) are emerging as new players in leukemogenic mechanisms. In patients with T-cell Acute Lymphoblastic Leukemia (T-ALL), the...
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The Notch pathway regulates KLF4 in podocyte injury induced by high glucose
BackgroundDiabetic nephropathy (DN) is a common complication of diabetes. The Notch pathway plays an important role in podocyte injury and decreases...
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Diagnostic value of the lateral femoral notch sign and kissing contusion in patients with anterior cruciate ligament injuries: a case–control study
IntroductionThe lateral femoral notch sign (LFNS) and the kissing contusion (KC) are two indirect signs of anterior cruciate ligament (ACL) injuries....
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The inter-individual anatomical variation of the trochlear notch as a predisposition for simple elbow dislocation
PurposeBesides the multi-layered capsule–ligamentous complex of the elbow joint the high bony congruence in the ulnohumeral joint contributes to...
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Knees with straight Blumensaat’s line have small volume of femoral intercondylar notch
PurposeSmaller femoral intercondylar notch volume has been identified as a risk factor for anterior cruciate ligament injury. The present study aims...
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TOB1 modulates the decidualization of human endometrial stromal cells via the Notch pathway
BackgroundDecidualization is critical for embryo implantation and the success of pregnancy; however, the mechanisms underlying this process remain...
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Altered expression of Notch signaling, Tlr receptors, and surfactant protein expression after prostaglandin inhibition may be associated with the delayed labor in LPS-induced mice
PurposeThis study aims to investigate whether indomethacin (IND) delays preterm birth by regulating the Notch pathway, Tlr receptors, and Sp-A in the...
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Analysis of intercondylar notch size and shape in patients with cyclops syndrome after anterior cruciate ligament reconstruction
BackgroundCyclops lesion is the second most common cause of extension loss after anterior cruciate ligament reconstruction. This study focused on the...
