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Detailed statistical analysis plan for ALBINO: effect of Allopurinol in addition to hypothermia for hypoxic-ischemic Brain Injury on Neurocognitive Outcome — a blinded randomized placebo-controlled parallel group multicenter trial for superiority (phase III)
BackgroundDespite therapeutic hypothermia (TH) and neonatal intensive care, 45–50% of children affected by moderate-to-severe neonatal...
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Fish oil-containing multicomponent lipid emulsion vs soy-based lipid emulsion and neurodevelopmental outcomes of children born < 29 weeks’ gestation
ObjectiveTo compare neurodevelopmental outcomes of extremely preterm children who received soy-medium chain triglycerides-olive-fish oil-containing...
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Neurodevelopmental outcomes following bevacizumab treatment for retinopathy of prematurity: a systematic review and meta-analysis
ObjectiveTo systematically review the studies exploring the association between bevacizumab and neurodevelopmental outcomes.
MethodsEmbase, Medline,...
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Impact of multiple placental pathologies on neonatal death, bronchopulmonary dysplasia, and neurodevelopmental impairment in preterm infants
BackgroundTo determine the association of placental pathology, including multiple placental lesions, with the occurrence and severity of...
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Maternal age and long-term neurodevelopmental outcomes of preterm infants < 29 weeks gestational age
ObjectiveThe objective of this study is to assess the impact of maternal age on neurodevelopmental (ND) outcomes of infants < 29 weeks gestational...
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Is late treatment with acetaminophen safe and effective in avoiding surgical ligation among extremely preterm neonates with persistent patent ductus arteriosus?
ObjectiveEvaluate the association of late treatment with acetaminophen vs. immediate surgical ligation with death or neurodevelopmental impairment...
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Relationship between biparietal diameter/ventricular ratio and neurodevelopmental outcomes in non-handicapped very preterm infants
PurposePreterm infants are at high risk for brain damage and long-term neurodevelopmental problems. Cranial ultrasonography is the main neuroimaging...
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The role of early-onset-sepsis in the neurodevelopment of very low birth weight infants
AimsThe study investigated a putative association between early-onset-sepsis (EOS) and poor neurodevelopmental outcomes at 2 years corrected age in...
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Growth and neuro-developmental outcomes of probiotic supplemented preterm infants—a systematic review and meta-analysis
Gut dysbiosis is associated with sepsis and necrotizing enterocolitis in preterm infants, which can adversely affect long-term growth and...
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Neonatal subgaleal hemorrhage: twenty years of trends in incidence, associations, and outcomes
BackgroundIn 2011, we reported 38 neonates with subgaleal hemorrhage (SH), relating an increasing incidence. It is unclear whether the incidence in...
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Timing of postnatal steroids for bronchopulmonary dysplasia: association with pulmonary and neurodevelopmental outcomes
ObjectiveTo determine the associations between age at first postnatal corticosteroids (PNS) exposure and risk for severe bronchopulmonary dysplasia...
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Early surgery in very preterm infants is associated with brain abnormalities on term MRI: a propensity score analysis
ObjectiveTo investigate the association between exposure to surgery under general anesthesia and brain abnormalities and neurodevelopmental outcomes...
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Association of growth with neurodevelopment in extremely low gestational age infants: a population-based analysis
To assess the association between postnatal growth and neurodevelopment at the age of 2 years in extremely low gestational age newborns...
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Anti-inflammatory effects of antenatal administration of stem cell derived extracellular vesicles in the brain of rat fetuses with congenital diaphragmatic hernia
PurposeCongenital diaphragmatic hernia (CDH) survivors may experience neurodevelopmental impairment, whose etiology remains elusive. Preclinical...
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The role of point-of-care ultrasound in the management of neonates with congenital diaphragmatic hernia
AbstractIn the last few years, current evidence has supported the use of point-of-care ultrasound (POCUS) for a number of diagnostic and procedural...
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Dynamic magnetic resonance imaging findings in the early stages of neonatal hypoglycemic brain injury
Hypoglycemia is common among neonates and can cause neurological dysfunction. This study aimed to identify the specific time window to perform...
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Transfusions and neurodevelopmental outcomes in extremely low gestation neonates enrolled in the PENUT Trial: a randomized clinical trial
BackgroundOutcomes of extremely low gestational age neonates (ELGANs) may be adversely impacted by packed red blood cell (pRBC) transfusions. We...
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Status of the neonatal follow-up system in China: survey and analysis
BackgroundThere is little information about neonatal follow-up programs (NFUPs) in China. This study aimed to conduct a survey of hospitals...
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Mode of delivery, perinatal outcome and neurodevelopment in uncomplicated monochorionic diamniotic twins: a single-center retrospective cohort study
BackgroundThere is no agreement on the effect of planned mode of delivery in the perinatal morbidity and neurodevelopment in uncomplicated...
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Bronchopulmonary dysplasia precursors influence risk of white matter injury and adverse neurodevelopmental outcome in preterm infants
BackgroundCumulative supplemental oxygen (CSO) and cumulative mean airway pressure (CMAP) are associated with bronchopulmonary dysplasia (BPD) in...