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Comparison of guidelines for prescription and follow-up of biologics for chronic rhinosinusitis with nasal polyps
PurposeTo compare international and regional guidelines for prescription and monitoring of response to biologics in chronic rhinosinusitis with nasal...
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Chronische Rhinosinusitis mit Polyposis nasi
BackgroundChronic rhinosinusitis with nasal polyps (CRSwNP) is a multifactorial inflammatory disease, the treatment of which has undergone...
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Slower Recovery with Early Lopinavir/Ritonavir use in Pediatric COVID-19 Patients: A Retrospective Observational Study
ObjectivesThere was initially insufficient understanding regarding suitable pharmacological treatment for pediatric Coronavirus Disease 2019...
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Omalizumab Treatment in Uncontrolled Asthma and CRSwNP Patients, with Previous Endoscopic Sinus Surgery, to Improve Quality of Life and Endoscopic Outcomes: a Two-Year Real-Life Study
Purpose of ReviewDespite molecular underlying advances, limited and divergent data on monoclonal antibodies (mAb) therapy in chronic rhinosinusitis...
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Comorbidities and clinical complications associated with SARS-CoV-2 infection: an overview
The novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes major challenges to the healthcare system. SARS-CoV-2 infection leads...
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Endoscopic Extended Sinus Surgery for Patients with Severe Chronic Rhinosinusitis with Nasal Polyps, the Choice of Mucoplasty: A Systematic Review
Purpose of ReviewThe advances in the knowledge of the molecular basis of the inflammatory response in chronic rhinosinusitis with nasal polyps...
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Efficacy and Safety of NSAIDs in Infants: A Comprehensive Review of the Literature of the Past 20 Years
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used in infants, children, and adolescents worldwide; however, despite sufficient...
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The “real life” efficacy of dupilumab is independent of initial polyp size and concomitant steroids in CRSwNP
BackgroundDupilumab significantly improves symptom control in chronic rhinosinusitis with nasal polyps (CRSwNP). Patients with large polyps at the...
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Refractory drug-induced systemic small-vessel vasculitis with two varied extracutaneous manifestations: a case report and review of the literature
BackgroundClopidogrel and ticagrelor are rarely reported to cause vasculitis via drug hypersensitivity reaction, largely mediated by T cells and...
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Dupilumab: A Review in Chronic Rhinosinusitis with Nasal Polyps
Dupilumab (Dupixent ® ) is a fully human IgG4 monoclonal antibody against the interleukin (IL)-4 receptor α (IL-4Rα) subunit, which is shared by the...
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Dupilumab: a delayed response in asthmatic and atopic patients treated for chronic rhinosinusitis with nasal polyps
PurposeChronic Rhinosinusitis with Nasal Polyps (CRSwNP) is a common disease, which was previously approached with sinus surgery or systemic...
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The time course of nasal cytokine secretion in patients with aspirin-exacerbated respiratory disease (AERD) undergoing aspirin desensitization: preliminary data
PurposeAspirin-exacerbated respiratory disease (AERD) is a severe form of chronic rhinosinusitis with nasal polyps (CRSwNP) accompanied by asthma and...
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Eosinophile in der HNO-Heilkunde: Freund oder Feind?
This article summarizes the essential aspects of current knowledge about eosinophils, classifies eosinophilia in terms of the dimensions healthy or...
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Headache Management in the Neuroscience Intensive Care Unit
Purpose of ReviewHeadache is a common symptom in the Neuroscience Intensive Care Unit (NeuroICU). Our goal is to provide an overview of approaches to...