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Inhibition effect of choline and parecoxib sodium on chronic constriction nerve injury-induced neuropathic pain in rats
PurposeThe simultaneous use of drugs with different mechanisms of analgesic action is a strategy for achieving effective pain control while...
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Pediatric Drug Hypersensitivity
Purpose of ReviewPediatric drug hypersensitivity is a rapidly evolving field. The purpose of this paper is to review the current state of pediatric...
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New Technical Aspects Used in the Management of Desensitization to Antineoplastic Drugs
Purpose of ReviewThis review will focus on the most recent technical developments in rapid drug desensitization to antineoplastic agents...
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Toxic myocarditis presenting as an acute coronary syndrome
BackgroundAcute myocarditis is one of the causes of acute non-ischemic myocardial injury mimicking acute coronary syndrome (ACS) on presentation. It...
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NSAIDs in sciatica (NIS): study protocol for an investigator-initiated multicentre, randomized placebo-controlled trial of naproxen in patients with sciatica
BackgroundNonsteroidal anti-inflammatory drugs (NSAIDs) are widely used to treat sciatica, despite insufficient evidence from placebo-controlled...
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Management of corneal melting after collagen cross-linking for keratoconus: a case report and a review of the literature
PurposeWe describe the management of a case of severe corneal melting after corneal cross-linking (CXL) treated with a staged approach using a...
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Medical ID use by international patients with Aspirin-Exacerbated Respiratory Disease
BackgroundPatients widely use medical identification (ID) to indicate their food and drug allergies, and chronic medical conditions. One chronic...
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Perioperative management of mastocytosis
PurposePatients with mastocytosis have an increased risk of anaphylaxis during surgical procedures with general anesthesia. Therefore, we reviewed...
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Post orgasmic illness syndrome: a review
POIS is a rare condition characterized by multisystem symptoms with unclear aetiology. Various attempts have been made to characterize this condition...
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Incidence, etiology, predictors and outcomes of suspected drug hypersensitivity reactions in a tertiary care university hospital’s emergency department
BackgroundAllergic drug reactions are adverse drug reactions that result from a specific immunologic response to a medication. Considering the...
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New Mechanistic Advances in FcεRI-Mast Cell–Mediated Allergic Signaling
Mast cells originate from the CD34 + /CD117 + hematopoietic progenitors in the bone marrow, migrate into circulation, and ultimately mature and reside...
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Demonstrating antibiotic stewardship while diagnosing and treating bilateral pseudoseptic arthritis: a case report
IntroductionAlthough viscosupplementation is a commonly used treatment for osteoarthritis and is widely regarded as a safe treatment option, it is...
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Coronary Artery Disease and Aspirin Intolerance: Background and Insights on Current Management
Aspirin is one of the most widely used medications across the global healthcare system and is the foundation in treating ischemic heart disease, as...
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Efficacy and Safety of NSAIDs in Infants: A Comprehensive Review of the Literature of the Past 20 Years
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used in infants, children, and adolescents worldwide; however, despite sufficient...
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Burden of Renal Events Associated with Nonsteroidal Anti-inflammatory Drugs in Patients with Osteoarthritis and Chronic Low Back Pain: A Retrospective Database Study
IntroductionNonsteroidal anti-inflammatory drugs (NSAIDs) have long-term benefits but are limited by side effects. We assessed the health and...
