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Promotion and Mechanism of Acupotomy on Chondrocyte Autophagy in Knee Osteoarthritis Rabbits
ObjectiveTo explore the effect of acupotomy intervention on autophagy of chondrocytes in rabbits with knee osteoarthritis (KOA), and to determine the...
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Exploring the Efficacy of Biologics in Knee Osteoarthritis: Ultrasound Evaluation of Cartilage Regeneration Effects
IntroductionBiologics like growth factors, stem cells, and platelet-rich plasma show potential in stimulating cartilage regrowth and reducing...
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Assessment of a novel deep learning-based software developed for automatic feature extraction and grading of radiographic knee osteoarthritis
BackgroundThe Kellgren-Lawrence (KL) grading system is the most widely used method to classify the severity of osteoarthritis (OA) of the knee....
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Lateral versus medial approach for total knee arthroplasty for valgus knee deformity shows comparable functional outcomes, hip–knee–ankle angle values, and complication rates: a meta-analysis of comparative studies
IntroductionThe aim of this meta-analysis of comparative studies was to update the current evidence on functional and radiographic outcomes and...
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Analgesic efficacy of collagen peptide in knee osteoarthritis: a meta-analysis of randomized controlled trials
BackgroundThe management of knee osteoarthritis involves various treatment strategies. It is important to explore alternative therapies that are both...
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Associations amongst dynamic knee stiffness during gait, quadriceps stiffness, and the incidence of knee osteoarthritis over 24 months: a cohort study with a mediation analysis
BackgroundDecreased strength and increased stiffness of the quadriceps have been associated with a higher risk of develo** knee osteoarthritis (OA)...
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Relationship between spinal imbalance and knee osteoarthritis by using full-body EOS
BackgroundOrthostatic state is maintained by harmonizing the spine, pelvis and lower extremities. In the past few decades, several studies have...
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Non-Arthroplasty Surgical Treatments for Knee Osteoarthritis and Cartilage Damage: a 10 Year Update
Osteoarthritis is a chronic, degenerative disease leading to pain and decreased functionality in millions of people in the United States every year....
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Subchondral bone in knee osteoarthritis: bystander or treatment target?
The subchondral bone is an important structural component of the knee joint relevant for osteoarthritis (OA) incidence and progression once disease...
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Effect of weight loss on knee joint synovitis over 48 months and mediation by subcutaneous fat around the knee: data from the Osteoarthritis Initiative
BackgroundObesity influences the development of osteoarthritis via low-grade inflammation. Progression of local inflammation (= synovitis) increased...
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Functional gait analysis reveals insufficient hindfoot compensation for varus and valgus osteoarthritis of the knee
PurposeThe hindfoot is believed to compensate varus and valgus deformities of the knee by eversion and inversion movements. But these mechanisms were...
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Phenotype-considered kinematically aligned total knee arthroplasty for windswept-deformity-associated osteoarthritis: surgical strategy and clinical outcomes
BackgroundWindswept deformity (WSD) in relation to advanced osteoarthritis (OA) presents a significant surgical challenge in total knee arthroplasty...
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The association between tibial torsion, knee flexion excursion and foot progression during gait in people with knee osteoarthritis: a cross-sectional study
BackgroundLower limb malalignment is associated with gait kinematics, but there is limited information on the relationship between gait kinematics...
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Efficacy of Mulligan joint mobilizations and trunk stabilization exercises versus isometric knee strengthening in the management of knee osteoarthritis: a randomized controlled trial
BackgroundKnee osteoarthritis (KOA) progression is often influenced by biomechanical factors. Biomechanical interventions, such as Trunk...
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Quadriceps strength is negatively associated with knee joint structural abnormalities—data from osteoarthritis initiative
ObjectiveThe aim of this study was to explore the longitudinal associations between baseline quadriceps strength and knee joint structural...
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Unicompartmental knee arthroplasty vs. high tibial osteotomy for medial knee osteoarthritis (UNIKORN): a study protocol of a randomized controlled trial
BackgroundMedial knee osteoarthritis (OA) is a common health problem resulting in knee pain and limiting patients’ physical activity. After failed...
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Maximum flexion and lateral rollback revealed better patient satisfaction after total knee arthroplasty
IntroductionPatient satisfaction is an important outcome of total knee arthroplasty (TKA). However, we cannot predict how and why patients are...
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Demographic and radiographic factors for knee symptoms and range of motion in patients with knee osteoarthritis: a cross-sectional study in Bei**g, China
BackgroundKnee osteoarthritis (KOA) causes not only pain, stiffness, and dysfunction of the knee, but also the reduction of the joint range of motion...
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The effectiveness of a 6-week biofeedback gait retraining programme in people with knee osteoarthritis: protocol for a randomised controlled trial
BackgroundGait retraining is a common therapeutic intervention that can alter gait characteristics to reduce knee loading in knee osteoarthritis...
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Interactions of cumulative load with biomarkers of cartilage turnover predict knee cartilage change over 2 years: data from the osteoarthritis initiative
The purpose was to investigate relationships of cumulative load and cartilage turnover biomarkers with 2-year changes in cartilage in knee...
