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Quick and improved immune responses to inactivated H9N2 avian influenza vaccine by purified active fraction of Albizia julibrissin saponins
BackgroundH9N2 Low pathogenic avian influenza virus (LPAIV) raises public health concerns and its eradication in poultry becomes even more important...
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Detecting influenza and emerging avian influenza virus by influenza and pneumonia surveillance systems in a large city in China, 2005 to 2016
BackgroundDetecting avian influenza virus has become an important public health strategy for controlling the emerging infectious disease.
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Sinensetin suppresses influenza a virus-triggered inflammation through inhibition of NF-κB and MAPKs signalings
BackgroundHuman respiratory system infected with influenza A virus (IAV) elicited a robust pro-inflammatory response that resulted in severe illness...
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Rapid and simple colorimetric detection of multiple influenza viruses infecting humans using a reverse transcriptional loop-mediated isothermal amplification (RT-LAMP) diagnostic platform
BackgroundIn addition to seasonal influenza viruses recently circulating in humans, avian influenza viruses (AIVs) of H5N1, H5N6 and H7N9 subtypes...
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Small-scale spatiotemporal epidemiology of notifiable infectious diseases in China: a systematic review
BackgroundThe prevalence of infectious diseases remains one of the major challenges faced by the Chinese health sector. Policymakers have a...
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Preparing intensive care for the next pandemic influenza
Few viruses have shaped the course of human history more than influenza viruses. A century since the 1918–1919 Spanish influenza pandemic—the largest...
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Inside-out assembly of viral antigens for the enhanced vaccination
Current attempts in vaccine delivery systems concentrate on replicating the natural dissemination of live pathogens, but neglect that pathogens...
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Progress in public health risk communication in China: lessons learned from SARS to H7N9
BackgroundFollowing the SARS outbreak, the World Health Organization revised the International Health Regulations to include risk communication as...
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Investigational Use of Mesenchymal Stem/Stromal Cells and Their Secretome as Add-On Therapy in Severe Respiratory Virus Infections: Challenges and Perspectives
Serious manifestations of respiratory virus infections such as influenza and coronavirus disease 2019 (COVID-19) are associated with a dysregulated...
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Influenza
Influenza continues to baffle humans by its constantly changing nature. The twenty-first century has witnessed considerable advances in the...
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Identification of two residues within the NS1 of H7N9 influenza A virus that critically affect the protein stability and function
The emerging avian-origin H7N9 influenza A virus, which causes mild to lethal human respiratory disease, continues to circulate in China, posing a...
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One health insights to prevent the next HxNy viral outbreak: learning from the epidemiology of H7N9
BackgroundWith an increased incidence of viral zoonoses, there is an impetus to strengthen collaborations between public health, agricultural and...
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Impact of corticosteroid treatment on clinical outcomes of influenza-associated ARDS: a nationwide multicenter study
BackgroundCorticosteroid treatment has been widely used in the treatment of septic shock, influenza, and ARDS, although some previous studies...
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Strengthened Monitoring of H5 Avian Influenza Viruses in External Environment in Hubei, 2018
The contamination status of H5 avian influenza viruses and distribution of subtypes of H5N1 and H5N6 in poultry-related environment of Hubei areas...
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Non-pharmaceutical interventions for COVID-19 reduced the incidence of infectious diseases: a controlled interrupted time-series study
BackgroundNon-pharmaceutical interventions (NPIs) have been implemented worldwide to suppress the spread of coronavirus disease 2019 (COVID-19)....
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Analysis of the microRNA expression profiles of chicken dendritic cells in response to H9N2 avian influenza virus infection
MicroRNA (miRNA) plays a key role in virus-host interactions. Here, we employed deep sequencing technology to determine cellular miRNA expression...
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Efficacy and practice of facemask use in general population: a systematic review and meta-analysis
In recent decades, respiratory infections, including SARS, HINI and the currently spreading COVID-19, caused by various viruses such as influenza and...
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Host DNA released by NETosis in neutrophils exposed to seasonal H1N1 and highly pathogenic H5N1 influenza viruses
BackgroundNeutrophil is of the most abundant number in human immune system. During acute influenza virus infection, neutrophils are already active in...
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Experiences and management of physician psychological symptoms during infectious disease outbreaks: a rapid review
BackgroundPrior to the COVID-19 pandemic, physicians experienced unprecedented levels of burnout. The uncertainty of the ongoing COVID-19 pandemic...
