Search
Search Results
-
Mitigation of letrozole induced polycystic ovarian syndrome associated inflammatory response and endocrinal dysfunction by Vitex negundo seeds
BackgroundPolycystic ovary syndrome (PCOS) is a complex endocrine disorder in women that necessitates effective and safe treatment alternatives. This...
-
Effect of melatonin supplementation on cardiometabolic risk factors, oxidative stress and hormonal profile in PCOS patients: a systematic review and meta-analysis of randomized clinical trials
BackgroundTo investigate whether melatonin supplementation can enhance cardiometabolic risk factors, reduce oxidative stress, and improve hormonal...
-
New insights gained from cellular landscape changes in myocarditis and inflammatory cardiomyopathy
Advances in the etiological classification of myocarditis and inflammatory cardiomyopathy (ICM) have reached a consensus. However, the mechanism of...
-
IL-10-providing B cells govern pro-inflammatory activity of macrophages and microglia in CNS autoimmunity
B cells contribute to chronic inflammatory conditions as source of antibody-secreting plasma cells and as antigen-presenting cells activating...
-
-
Inhibition of Bcl-6 Expression Ameliorates Asthmatic Characteristics in Mice
ObjectiveThe function of Bcl-6 in T follicular helper (Tfh) cell maturation is indispensable, and Tfh cells play a pivotal role in asthma. This study...
-
Neuropeptide Y directly reduced apoptosis of granulosa cells, and the expression of NPY and its receptors in PCOS subjects
BackgroundMost women with anovulatory infertility show polycystic ovarian syndrome (PCOS), and androgen excess is known as a key factor involved in...
-
ApoC3 is expressed in oocytes and increased expression is associated with PCOS progression
BackgroundPolycystic ovary syndrome (PCOS) is a lifelong metabolic disorder and the most common cause of anovulatory infertility affecting women in...
-
Comparison of allergy prevalence using brinzolamide 1.0% / brimonidine 0.2% fixed combination with and without β-blocker in glaucoma patients: a retrospective cohort study
BackgroundGlaucoma treatment often involves multi-drug regimens, which can lead to poor adherence and side effects. Fixed-dose combinations aim to...
-
Effect of Endometrioma cystectomy on cytokines of follicular fluid and IVF outcomes
BackgroundEndometriosis patients undergoing in vitro fertilization-embryo transfer (IVF-ET) treatment suffer from lower success rates. The success of...
-
BTK inhibitors in the treatment of hematological malignancies and inflammatory diseases: mechanisms and clinical studies
Bruton’s tyrosine kinase (BTK) is an essential component of multiple signaling pathways that regulate B cell and myeloid cell proliferation,...
-
Pathogenic Autoimmunity in Atherosclerosis Evolves from HSP60-Reactive CD4 + T Cells
Clinical evidence suggests anti-Hsp60 antibodies could contribute to atherosclerosis (AS) development, with unclear mechanisms. This study aims to...
-
Conception, pregnancy and inflammatory bowel disease—Current concepts for the practising clinician
The peak incidence of inflammatory bowel disease (IBD) coincides with a woman’s prime reproductive years. The management of IBD during pregnancy can...
-
A review of nitric oxide and oxidative stress in typical ovulatory women and in the pathogenesis of ovulatory dysfunction in PCOS
Polycystic ovary syndrome (PCOS) is a heterogeneous functional endocrine disorder associated with a low-grade, chronic inflammatory state. Patients...
-
Systemic inflammatory autoimmune disease before allogeneic hematopoietic stem cell transplantation is a risk factor for death in patients with myelodysplastic syndrome or chronic myelomonocytic leukemia
Myelodysplastic syndrome (MDS) is well known to be complicated by systemic inflammatory autoimmune disease (SIADs). However, it remains unclear how...
-
25(OH)D3 improves granulosa cell proliferation and IVF pregnancy outcomes in patients with endometriosis by increasing G2M+S phase cells
BackgroundThe 25-hydroxyvitamin D3 (25 (OH) D3) is crucial for follicular development. This study aimed to investigate the relationship between the...
-
Meningeal inflammation as a driver of cortical grey matter pathology and clinical progression in multiple sclerosis
Growing evidence from cerebrospinal fluid samples and post-mortem brain tissue from individuals with multiple sclerosis (MS) and rodent models...
-
The degree of risk factor and accumulation effect for large niche in individuals after cesarean section
BackgroundThe risk factors associated with niche on the cesarean scar have been reported, however, the degree of these factors associated with large...
-
Bariatric Surgery and Inflammatory Bowel Disease: National Trends and Outcomes Associated with Procedural Sleeve Gastrectomy vs Historical Bariatric Surgery Among US Hospitalized Patients 2009–2020
Abstract PurposeThe association between bariatric surgery and IBD-related inpatient outcomes is not well characterized. We report, analyze, and...
-
Immune cell profiles in synovial fluid after anterior cruciate ligament and meniscus injuries
BackgroundAnterior cruciate ligament (ACL) and meniscus tears are common knee injuries. Despite the high rate of post-traumatic osteoarthritis (PTOA)...
