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Risk factors for post-cerebral infarction cognitive dysfunction in older adults: a retrospective study
ObjectiveOur research aims to elucidate the significance of type 2 diabetes (T2D) and provides an insight into a novel risk model for post-cerebral...
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Quantification of lipoproteins by proton nuclear magnetic resonance spectroscopy (1H-NMRS) improves the prediction of cardiac autonomic dysfunction in patients with type 1 diabetes
AimsTo assess if advanced characterization of serum glycoprotein and lipoprotein profile, measured by proton nuclear magnetic resonance spectroscopy (
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Higher testosterone is associated with increased inflammatory markers in women with SARS-CoV-2 pneumonia: preliminary results from an observational study
PurposeObjective of this study was to assess the association between testosterone (T) levels and biochemical markers in a cohort of female patients...
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Development and validation of a nomogram for predicting deep venous thrombosis in patients with pelvic and acetabular fractures: a retrospective cohort study
PurposeTo construct a novel nomogram model that can predict DVT and avoid unnecessary examination.
MethodsPatients admitted to the hospital with...
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Low FXIII activity levels in intensive care unit hospitalized COVID-19 patients
BackgroundCOVID-19 infection is associated with a hypercoagulable state. Severe COVID-19 patients present with high plasma fibrinogen levels,...
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Evaluation of disease severity and prediction of severe cases in children hospitalized with influenza A (H1N1) infection during the post-COVID-19 era: a multicenter retrospective study
BackgroundThe rebound of influenza A (H1N1) infection in post-COVID-19 era recently attracted enormous attention due the rapidly increased number of...
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Type IV collagen turnover is predictive of mortality in COPD: a comparison to fibrinogen in a prospective analysis of the ECLIPSE cohort
BackgroundIdentifying subjects with chronic obstructive pulmonary disease (COPD) at high risk of exacerbation and mortality is key to aid individual...
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An integrated framework for identifying clinical-laboratory indicators for novel pandemics: COVID-19 and MIS-C
During the critical early stages of an emerging pandemic, limited availability of pathogen-specific testing can severely inhibit individualized risk...
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Clinical Frailty Scale and Biomarkers for Assessing Frailty in Elder Inpatients in China
ObjectiveThis study aimed to assess the feasibility of the Clinical Frailty Scale (CFS) and clinical biomarkers in assessing the frailty in elder...
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Prognostic value of platelet count-related ratios on admission in patients with pyogenic liver abscess
ObjectiveThe purpose of the current study was to evaluate the association between C-reactive protein-to-platelet ratio (CPR),...
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Effects of regional citrate anticoagulation on thrombin generation, fibrinolysis and platelet function in critically ill patients receiving continuous renal replacement therapy for acute kidney injury: a prospective study
BackgroundRegional citrate anticoagulation (RCA) is recommended for continuous renal replacement therapy (CRRT). However, filter life varies and...
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Proteomic associations with forced expiratory volume: a Mendelian randomisation study
BackgroundA decline in forced expiratory volume (FEV1) is a hallmark of respiratory diseases that are an important cause of morbidity among the...
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A randomized, controlled clinical study of low-molecular-weight heparin improving pregnancy outcomes in PCOS women undergoing IVF: study protocol
BackgroundPolycystic ovary syndrome (PCOS), an incidence of 10–15% in women of reproductive age, shows sex hormone disorders, luteal insufficiency,...
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The role of apheresis and insulin therapy in hypertriglyceridemic acute pancreatitis—a concise review
Severe hypertriglyceridemia (HTG) is the third most common cause of acute pancreatitis (AP) and is involved in its pathogenesis. Chylomicrons...
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Clinical significance of dynamic variation of low cholesterol and its prognostic value in patients with pyogenic liver abscesses: a retrospective study
BackgroundSerum lipids variations are closely related to the sepsis progression; however, their value for patients with pyogenic liver abscesses...
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Hymecromone: a clinical prescription hyaluronan inhibitor for efficiently blocking COVID-19 progression
Currently, there is no effective drugs for treating clinically COVID-19 except dexamethasone. We previously revealed that human identical sequences...
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Immunogenicity and clinical features relating to BNT162b2 messenger RNA COVID-19 vaccine, Ad26.COV2.S and ChAdOx1 adenoviral vector COVID-19 vaccines: a systematic review of non-interventional studies
BackgroundVaccination against Coronavirus disease 2019 (COVID-19) is an important means of controlling the pandemic, however they are expected to...
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Critical role of acute hypoxemia on the cognitive impairment after severe COVID-19 pneumonia: a multivariate causality model analysis
BackgroundA high proportion of coronavirus disease 2019 (COVID-19) survivors may develop long-term cognitive impairment. We aimed to develop a...
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Is it required to routinely check fibrinogen level in patients with rheumatic diseases on tocilizumab? Case-based review
Tocilizumab (TCZ) may rarely cause hematological side effects including neutropenia and thrombocytopenia. TCZ is essentially expected to lower the...
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