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1. Isorhamnetin Downregulates MMP2 and MMP9 to Inhibit Development of Rheumatoid Arthritis through SRC/ERK/CREB Pathway

   Objective

   To investigate the effect of isorhamnetin on the pathology of rheumatoid arthritis (RA).

   Methods

   Tumor necrosis factor (TNF)- α -induced...

   **ao-rong Liu, Shuo-fu Li, ... Ri-bao Zhou in Chinese Journal of Integrative Medicine

   Article 12 January 2024

2. Mechanistic target of rapamycin (mTOR): a potential new therapeutic target for rheumatoid arthritis

   Rheumatoid arthritis (RA) is an autoimmune disease characterized by systemic synovitis and bone destruction. Proinflammatory cytokines activate...

   Fen Zhang, Ting Cheng, Sheng-**ao Zhang in Arthritis Research & Therapy

   Article Open access 02 October 2023
   

3. Pneumocystosis in a patient with rheumatoid arthritis on adalimumab therapy: a case-based review

   Pneumocystis jirovecii pneumonia (PJP) is a potentially fatal type of pneumonitis, which may have devastating consequences. Typically, it occurs in...

   Dimitris C. Kounatidis, Vasileios Papadimitropoulos, ... Dimitrios Vassilopoulos in Rheumatology International

   Article 18 October 2023
   

4. Salt Behind the Scenes of Systemic Lupus Erythematosus and Rheumatoid Arthritis

   Purpose of Review

   Sodium is vital for human health. High salt intake is a global health problem and is associated with cardiovascular morbidity and...

   Baris Afsar, Rengin Elsurer Afsar in Current Nutrition Reports

   Article 18 November 2023
   

5. The relationship between clinical phenotype and kallikrein-kinin bioregulation in different forms of arthritis

   Objective

   Patients with rheumatoid arthritis (RA) have shown increased levels of neutrophils generating kallikrein-kinin peptides in blood which are...

   Dino B. A. Tan, Chantalia Tedja, ... Helen I. Keen in BMC Musculoskeletal Disorders

   Article Open access 18 May 2023

6. Juvenile idiopathic arthritis

   Juvenile idiopathic arthritis (JIA) is an umbrella term for arthritis of unknown origin, lasting for >6 weeks with onset before 16 years of age. JIA...

   Alberto Martini, Daniel J. Lovell, ... Nicolino Ruperto in Nature Reviews Disease Primers

   Article 27 January 2022
   

7. EC-18 prevents autoimmune arthritis by suppressing inflammatory cytokines and osteoclastogenesis

   Background

   EC-18, a synthetic monoacetyldiaglyceride, exhibits protective effects against lung inflammation, allergic asthma, and abdominal sepsis....

   **-Sil Park, Seung Cheon Yang, ... Sung-Hwan Park in Arthritis Research & Therapy

   Article Open access 17 November 2022
   

8. The efficacy of low dose short-term prednisone therapy for remission induction in newly diagnosed rheumatoid arthritis patients

   Background

   The ACR/EULAR recommendations endorse the use of glucocorticoids (GCs) for rheumatoid arthritis (RA) patients’ flares and as a bridge to a...

   John M. Stacy, Jacob R. Greenmyer, ... Erdal Diri in Advances in Rheumatology

   Article Open access 09 August 2021
   

9. Extensive preclinical evaluation of combined mangiferin and glycyrrhizic acid for restricting synovial neovascularization in rheumatoid arthritis

   Background

   Synovial neovascularization promotes rheumatoid arthritis (RA) progression. Baihu guizhi decoction (BHGZD) has a potential in restricting...

   **a Mao, **angying Yan, ... Na Lin in Chinese Medicine

   Article Open access 30 November 2023
   

10. Sirtuin 6 ameliorates arthritis through modulating cyclic AMP-responsive element binding protein/CCN1/cyclooxygenase 2 pathway in osteoblasts

    Introduction

    CCN1 is an immediate-early gene product pivotal for arthritis progression. We have previously shown that sirtuin 6 (SIRT6) inhibited...

    Sze-Kwan Lin, Han-Wei Wang, ... Sang-Heng Kok in Journal of Bone and Mineral Metabolism

    Article 29 October 2023
    

11. Role of DNA dioxygenase Ten-Eleven translocation 3 (TET3) in rheumatoid arthritis progression

    Background

    Rheumatoid arthritis (RA) patients present with abnormal methylation patterns in their fibroblast-like synoviocytes (FLS). Given that DNA...

    Akio Kawabe, Kaoru Yamagata, ... Yoshiya Tanaka in Arthritis Research & Therapy

    Article Open access 16 September 2022
    

12. The role of interleukin (IL)-23 in regulating pain in arthritis

    Current understanding of IL-23 biology, with its link to other pro-inflammatory cytokines, for example, IL-17 and granulocyte macrophage-colony...

    Kevin M.-C. Lee, Jonathan P. Sherlock, John A. Hamilton in Arthritis Research & Therapy

    Article Open access 25 April 2022

13. Adherence to biological therapies in patients with rheumatoid arthritis: a retrospective cohort study

    The advent of biologic disease-modifying antirheumatic drugs has dramatically changed the comprehensions of treatment and long-term prognosis in...

    Stefka Neycheva, Emilia Naseva, ... Anastas Batalov in Rheumatology International

    Article 19 April 2023

14. Shared inflammatory pathways of rheumatoid arthritis and atherosclerotic cardiovascular disease

    The association between chronic inflammation and increased risk of cardiovascular disease in rheumatoid arthritis (RA) is well established. In the...

    Brittany N. Weber, Jon T. Giles, Katherine P. Liao in Nature Reviews Rheumatology

    Article 25 May 2023
    

15. Predominant ligament-centric soft-tissue involvement differentiates axial psoriatic arthritis from ankylosing spondylitis

    Since the original description of spondyloarthritis 50 years ago, results have demonstrated similarities and differences between ankylosing...

    Dennis McGonagle, Paula David, ... Abdulla Watad in Nature Reviews Rheumatology

    Article 02 November 2023
    

16. Comprehensive overview of microRNA function in rheumatoid arthritis

    MicroRNAs (miRNAs), a class of endogenous single-stranded short noncoding RNAs, have emerged as vital epigenetic regulators of both pathological and...

    **aole Peng, Qing Wang, ... Dechun Geng in Bone Research

    Article Open access 24 January 2023
    

17. Study on the mechanism of action of Wu Mei Pill in inhibiting rheumatoid arthritis through TLR4-NF-κB pathway

    Background

    Wu Mei Pills (WMP) is a traditional Chinese medication that exhibits considerable anti-inflammatory effects. While WMP has been documented...

    Yuheng Fu, Chunyu Gao, ... Haibo Zhang in Journal of Orthopaedic Surgery and Research

    Article Open access 13 January 2024
    

18. Radiological insights into rheumatoid meningitis – a rare central nervous system manifestation of rheumatoid arthritis: a retrospective review of six cases

    Background

    The objective is to analyze and review the clinical, laboratory, and neuroimaging characteristics of rheumatoid meningitis (RM) in six...

    Zhao Hui Chen Zhou, Amaya Hilario, ... Ana Ramos González in Neurological Sciences

    Article 15 May 2024
    

19. Metabolic reprogramming of proinflammatory macrophages by target delivered roburic acid effectively ameliorates rheumatoid arthritis symptoms

    Rheumatoid arthritis (RA) is a common chronic inflammatory disorder that usually affects joints. It was found that roburic acid (RBA), an ingredient...

    Na Jia, Yunzhen Gao, ... Ling Zhang in Signal Transduction and Targeted Therapy

    Article Open access 28 July 2023
    

20. Salidroside suppresses cell growth and inflammatory response of fibroblast-like synoviocytes via inhibition of phosphoinositol-3 kinase/threonine kinase signaling in rheumatoid arthritis

    Background

    Salidroside (Sal) is a natural product commonly isolated from Rhodiola rosea L., which has been found to have numerous pharmacological...

    Ya**g Qin, Juan Su in Zeitschrift für Rheumatologie

    Article 18 October 2023