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Haven’t lost the positive feeling: a dose-response, oral alcohol challenge study in drinkers with alcohol use disorder
Models of addiction are based on neurobiological, behavioral, and pharmacological studies in animals, but translational support from human studies is...
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Male-selective effects of oxytocin agonism on alcohol intake: behavioral assessment in socially housed prairie voles and involvement of RAGE
Targeting the oxytocin (OXT) peptide system has emerged as a promising new approach for the treatment of alcohol use disorder (AUD). However, further...
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The role of PPAR-γ in memory deficits induced by prenatal and lactation alcohol exposure in mice
Patients diagnosed with fetal alcohol spectrum disorder (FASD) show persistent cognitive disabilities, including memory deficits. However, the...
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The GlyT1-inhibitor Org 24598 facilitates the alcohol deprivation abolishing and dopamine elevating effects of bupropion + varenicline in rats
Alcohol Use Disorder (AUD) is a relapsing brain disorder that involves perturbations of brain dopamine (DA) systems, and combined treatment with...
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An Overview of Sex and Gender Considerations in Sleep and Alcohol Use
Purpose of ReviewThis paper explored the under-researched bidirectional alcohol/sleep link, examining sex and gender’s impact on this relationship...
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Spironolactone as a potential new pharmacotherapy for alcohol use disorder: convergent evidence from rodent and human studies
Evidence suggests that spironolactone, a nonselective mineralocorticoid receptor (MR) antagonist, modulates alcohol seeking and consumption....
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Alcohol-specific transcriptional dynamics of memory reconsolidation and relapse
Relapse, a critical issue in alcohol addiction, can be attenuated by disruption of alcohol-associated memories. Memories are thought to temporarily...
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Epigenetic drugs and psychedelics as emerging therapies for alcohol use disorder: insights from preclinical studies
Alcohol use disorder (AUD) is a public health issue that affects millions of people worldwide leading to physical, mental and socio-economic...
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Prenatal exposure to alcohol and its impact on reward processing and substance use in adulthood
Heavy maternal alcohol drinking during pregnancy has been associated with altered neurodevelopment in the child but the effects of low-dose alcohol...
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“I Thought Cancer was a Tobacco Issue”: Perspectives of Veterans with and without HIV on Cancer and Other Health Risks Associated with Alcohol and Tobacco/Nicotine Use
U.S. Veterans and people living with HIV (PWH) experience higher rates of unhealthy alcohol and tobacco/nicotine use than non-Veterans and people...
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An Updated Narrative Review on the Role of Alcohol Among Indigenous Communities
Purpose of ReviewThe role of alcohol varies considerably among Indigenous Peoples and is the backdrop of persistent stereotypes despite decades of...
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Hazardous drinking and alcohol use disorders
Alcohol is one of the most widely consumed psychoactive drugs globally. Hazardous drinking, defined by quantity and frequency of consumption, is...
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Adapting an Alcohol Care Linkage Intervention to US Military Veterans Presenting to Primary Care with Hazardous Drinking and PTSD and/or Depression Symptoms: A Qualitative Study
There is a critical need to improve linkage to alcohol care for veterans in primary care with hazardous drinking and PTSD and/or depression symptoms...
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The intersection between alcohol-related liver disease and nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) and alcohol-related liver disease (ALD) are the leading causes of chronic liver disease worldwide. NAFLD and...
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Leucine-rich repeat kinase 2 limits dopamine D1 receptor signaling in striatum and biases against heavy persistent alcohol drinking
The transition from hedonic alcohol drinking to problematic drinking is a hallmark of alcohol use disorder that occurs only in a subset of drinkers....
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Treatment Referrals Post-prohibition of Alcohol Exclusion Laws: Evidence from Colorado and Illinois
BackgroundIndividuals with alcohol-related disorders often encounter barriers to accessing treatment. One potential barrier is the state alcohol...
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Within and Beyond the Binary: Sex and Gender Differences in Pain and Alcohol Use Disorder
Purpose of ReviewAlcohol use disorder (AUD) and chronic pain are frequently comorbid conditions. This review aims to communicate recent research...
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Intoxicating effects of alcohol depend on acid-sensing ion channels
Persons at risk for develo** alcohol use disorder (AUD) differ in their sensitivity to acute alcohol intoxication. Alcohol effects are complex and...
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A Narrative Review of Emotion Regulation Abilities, Strategy Use, and Their Relationship to Alcohol
Purpose of ReviewPoor emotion regulation (ER) abilities are associated with co** motives, alcohol use problems, and difficulties recovering from an...
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Predictors of Alcohol Use Among Latinx Men in South Florida: Machismo as a Correlate of Alcohol Use Frequency and Quantity
Previous studies have found Latinx cultural values to be positively associated with healthy behaviors. This study aims to examine socioeconomic and...