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Evaluation of vitamin D levels and affecting factors of vitamin D deficiency in healthy children 0–18 years old
The frequency of vitamin D deficiency in healthy children is relatively high. Moreover, vitamin D supplementation in children is under the requested...
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The effect of vitamin D3 and thyroid hormones on the capillaroscopy-confirmed microangiopathy in pediatric patients with a suspicion of systemic connective tissue disease-a single-center experience with Raynaud phenomenon
Raynaud phenomenon (RP) may be the first manifestation of a systemic connective tissue disease (SCTD). Early detection of dysfunction of small...
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Involvement of the secosteroid vitamin D in autoimmune rheumatic diseases and COVID-19
Evidence supporting the extra-skeletal role of vitamin D in modulating immune responses is centred on the effects of its final metabolite,...
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Vitamin D and Toxic Metals in Pregnancy - a Biological Perspective
Purpose of ReviewTo discuss the potential biological mechanisms between vitamin D and toxic metals and summarize epidemiological studies examining...
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Update on vitamin D role in severe infections and sepsis
Severe infections frequently require admission to the intensive care unit and cause life-threatening complications in critically ill patients. In...
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Increased integrity of cell–cell junctions accompanied by increased expression of claudin 4 in keratinocytes stimulated with vitamin D3
The stratified squamous epithelium has a multilayer structure formed by the differentiation of the keratinized epithelium, which covers the skin and...
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Vitamin D and reproductive disorders: a comprehensive review with a focus on endometriosis
Vitamin D is a fat-soluble steroid hormone that was initially known only for regulating calcium and phosphorus levels and maintaining bone health....
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Dietary vitamin D intake and risk of colorectal cancer according to vitamin D receptor expression in tumors and their surrounding stroma
BackgroundColorectal Cancer (CRC) has been molecularly classified into several subtypes according to tumor, stromal, and immune components. Here, we...
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The effects of Vitamin D3 supplementation on Spermatogram and endocrine factors in asthenozoospermia infertile men: a randomized, triple blind, placebo-controlled clinical trial
ObjectiveEvaluate the effects of vitamin D3 (VD3) on sperm parameters and endocrine markers in infertile men with asthenozoospermia.
Materials and...
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Plain vitamin D or active vitamin D in the treatment of osteoporosis: where do we stand today?
Osteoporosis is a major cause of morbidity and mortality worldwide and its prevention in order to avert fractures was considered of great importance...
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Vitamin D status and supplementation before and after Bariatric Surgery: Recommendations based on a systematic review and meta-analysis
Bariatric surgery is associated with a postoperative reduction of 25(OH) vitamin D levels (25(OH)D) and with skeletal complications. Currently,...
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Long-term effects of vitamin D supplementation and maintaining sufficient vitamin D on knee osteoarthritis over 5 years
ObjectivesThis study aimed to investigate the long-term effect of vitamin D supplementation compared to placebo over 5 years in participants with...
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Vitamin D and human health: evidence from Mendelian randomization studies
We summarized the current evidence on vitamin D and major health outcomes from Mendelian randomization (MR) studies. PubMed and Embase were searched...
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Vitamin D and the microbiota connection: understanding its potential to improve COPD outcomes
The mucosa of the respiratory system is an essential site for local vitamin D synthesis, degradation, and signaling. It modulates the inflammatory...
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What is known about the effects of vitamin D in neuropsychiatric lupus?
Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect several organs and systems. The central and/or peripheral nervous system...
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High-dose vitamin D3 supplementation shows no beneficial effects on white blood cell counts, acute phase reactants, or frequency of respiratory infections
BackgroundVitamin D has been suggested to influence the immune system, and vitamin D metabolites and the vitamin D receptor (VDR) are generated and...
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Multiple electrolytes imbalances in a patient with inflammatory bowel disease associated with vitamin D deficiency: a case report
BackgroundInflammatory bowel disease involves chronic inflammation and ulceration, primarily Crohn’s disease and ulcerative colitis. The prevalence...
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Sex-dependent association of serum vitamin D with muscle strength in older adults: NHANES 2001–2002
BackgroundAlthough several studies have suggested a potential positive association between serum vitamin D levels and muscle strength in older...
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1,25-Dihydroxyvitamin D3 alleviates hyperandrogen-induced ferroptosis in KGN cells
PurposeHyperandrogenism, one of the most frequent causes of anovulation in women, increases the risk of metabolic disorders in patients with...
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Schützt Vitamin D vor COVID-19? Eine beschreibende Übersicht
The pleiotropic effects of Vitamin D (or rather its active metabolite calcitriol) on the immune system and the lung suggest a preventive and...
