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Dynamic Role of miRNAs in Salivary Gland Carcinomas: From Biomarkers to Therapeutic Targets
BackgroundSalivary gland carcinomas (SGCs) are a rare group of malignant neoplasms of the head and neck region. MicroRNAs (miRNAs) are a class of...
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Liquid biopsy using non-coding RNAs and extracellular vesicles for breast cancer management
This article examines liquid biopsy using non-coding RNAs and extracellular vesicles in detail. Liquid biopsy is emerging as a prominent non-invasive...
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Roles of non-coding RNA in diabetic cardiomyopathy
In recent years, the incidence of diabetes has been increasing rapidly, posing a serious threat to human health. Diabetic cardiomyopathy (DCM) is...
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Endothelin-3 is epigenetically silenced in endometrioid endometrial cancer
PurposeChanges in the activity of endothelins and their receptors may promote neoplastic processes. They can be caused by epigenetic modifications...
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Gray matter volume and microRNA levels in patients with attention-deficit/hyperactivity disorder
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder often characterized by gray matter (GM) volume reductions....
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Using the Precision Lasso for gene selection in diffuse large B cell lymphoma cancer
BackgroundGene selection from gene expression profiles is the appropriate tool for diagnosing and predicting cancers. The aim of this study is to...
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Profiling miRNAs in tear extracellular vesicles: a pilot study with implications for diagnosis of ocular diseases
PurposeTo estimate the roles of extracellular vesicles (EVs) in tears and to determine whether their profiles are associated with the type of ocular...
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Non-coding RNAs in leukemia drug resistance: new perspectives on molecular mechanisms and signaling pathways
Like almost all cancer types, timely diagnosis is needed for leukemias to be effectively cured. Drug efflux, attenuated drug uptake, altered drug...
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The role of non-coding RNAs in extracellular vesicles in breast cancer and their diagnostic implications
Breast Cancer (BC) is the most common form of cancer worldwide, responsible for 25% of cancers in women. Whilst treatment is effective and often...
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miRNAs in decidual NK cells: regulators worthy of attention during pregnancy
The critical immune effectors, including T, B, and natural killer (NK) cells, dendritic cells, and macrophages participate in regulating immune...
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Unraveling the microRNAs, key players in folliculogenesis and ovarian diseases
BackgroundFolliculogenesis is an intricate process that involves the development and maturation of ovarian follicles in females. During...
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Prognostic implication of downregulated exosomal miRNAs in patients with sepsis: a cross-sectional study with bioinformatics analysis
BackgroundDespite the understanding of sepsis-induced extracellular vesicles (EVs), such as exosomes, and their role in intercellular communication...
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Updates on the role of epigenetics in familial mediterranean fever (FMF)
Familial Mediterranean Fever (FMF) is an autosomal recessive autoinflammatory disease caused by mutations in the MEFV ( ME diterranean F e V er) gene that...
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Predictive value of circulating coagulation related microRNAs expressions for major adverse cardiac and cerebral event risk in patients undergoing continuous ambulatory peritoneal dialysis: a cohort study
BackgroundWe aimed to investigate the correlation of coagulation related microRNAs (miRNAs) expressions with major adverse cardiac and cerebral event...
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miRNAs as biomarkers of autism spectrum disorder: a systematic review and meta-analysis
Autism spectrum disorder (ASD) is a neurodevelopmental disorder with complex clinical manifestations that arise between 18 and 36 months of age....
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Secreted microRNAs in bone metastasis
Bone metastasis is a common complication in several solid cancers, including breast, prostate, and lung. In the bone microenvironment, metastatic...
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LncRNA HOTTIP impacts the proliferation and differentiation of fibroblast-like synoviocytes in ankylosing spondylitis through the microRNA-30b-3p/PGK1 axis
ObjectiveLong non-coding RNAs (lncRNAs) and microRNAs (miRNAs) have been reported to exert regulatory effects on biological processes. This study...
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MicroRNA based combinatorial therapy against TKIs resistant CML by inactivating the PI3K/Akt/mTOR pathway: a review
Chronic myeloid leukemia (CML) is characterized by presence of Philadelphia chromosome, which harbors BCR-ABL oncogene responsible for encoding...
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Exosomal microRNAs in Parkinson’s disease: insights into biomarker potential and disease pathology
Parkinson’s disease (PD) is a prevalent neurodegenerative condition primarily affecting the elderly population. Despite its high incidence in aged...
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A literature review of microRNA and gene signaling pathways involved in the apoptosis pathway of lung cancer
BackgroundLung cancer is one of the leading causes of death in the world and the deadliest of all cancers. Apoptosis is a key pathway in regulating...
