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The efficacy of switching basal–bolus insulin therapy to basal insulin-supported oral therapy with a glinide and an α-glucosidase inhibitor in patients with type 2 diabetes depends on insulin secretory capacity, but not on blood glucose profiles and insulin dosages prior to the switching
AimsWe aimed to identify patients who would benefit from basal insulin-supported oral therapy (BOT) with a glinide and an α-glucosidase inhibitor (a...
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Continuous glucose monitoring data for artificial intelligence-based predictive glycemic event: A potential aspect for diabetic care
BackgroundDiabetes mellitus is a chronic metabolic disorder that affects 537 million of the population worldwide whereby continuous glucose...
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Glucose and HbA1c variability and time in range (TIR)
Glycated hemoglobin (HbA1c) is the pillar of diabetes management, but does not capture blood glucose fluctuations over time. Recent data suggest that...
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Postoperative fasting plasma glucose and family history diabetes mellitus can predict post-transplantation diabetes mellitus in kidney transplant recipients
PurposeTo explore whether glycated albumin (GA) or fasting plasma glucose (FPG), both routinely monitored during patients’ hospital stay, can be used...
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Absence of fluctuation and inverted circadian rhythm of blood pressure increase the risk of cognitive dysfunction in cerebral small vessel disease patients
Background and purposeCerebral small vessel disease (CSVD) is a common cause of stroke and senile vascular cognitive impairment, imposing a heavy...
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Time in Range Estimation in Patients with Type 2 Diabetes is Improved by Incorporating Fasting and Postprandial Glucose Levels
IntroductionTime in range (TIR) as assessed by continuous glucose monitoring (CGM) measures an individual’s glucose fluctuations within set limits in...
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Effects of intermittently scanned continuous glucose monitoring on blood glucose control and the production of urinary ketone bodies in pregestational diabetes mellitus
ObjectiveTo investigate the effects of intermittently scanned continuous glucose monitoring (isCGM) on blood glucose control, clinical value of blood...
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Performance Evaluation of the Glunovo® Continuous Blood Glucose Monitoring System in Chinese Participants with Diabetes: A Multicenter, Self-Controlled Trial
IntroductionThe present study was aimed to evaluate the performance and safety of the Glunovo® real-time continuous glucose monitoring system (CGMS)...
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Glucose fluctuations aggravate myocardial fibrosis via activating the CaMKII/Stat3 signaling in type 2 diabtetes
BackgroundGlucose fluctuations (GF) are a risk factor for cardiovascular complications associated with type 2 diabetes. However, there is a lack of...
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A Prospective Longitudinal Study on the Relationship Between Glucose Fluctuation and Cognitive Function in Type 2 Diabetes: PROPOSAL Study Protocol
IntroductionAlthough the risk of dementia among patients with type 2 diabetes mellitus (T2DM) is double that of those without T2DM, the mechanism...
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The efficacy of intraoperatie continuous glucose monitoring in patients undergoing liver transplantation: a study protocol for a prospective randomized controlled superiority trial
BackgroundThe high incidence of intraoperative glucose dysregulations in liver transplantation (LT) is related to the lack of highly orchestrated...
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Use of Continuous Glucose Monitoring in Patients Following Bariatric Surgery: A Sco** Review
The objective of this sco** review was to summarize the emerging literature on the use of continuous glucose monitoring (CGM) in post-bariatric...
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Effect of lunch with different calorie and nutrient balances on dinner-induced postprandial glucose variability
AimThis study aimed to examine the effect of lunches with different caloric contents (Study 1) and nutrient balances (Study 2) on dinner-induced...
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Visit-to-visit fasting blood glucose variability and lifetime risk of cardiovascular disease: a prospective study
AimsPrevious studies suggested an adverse association between higher fasting blood glucose (FBG) variability and cardiovascular disease (CVD)....
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Abnormal cerebral blood flow and brain function in type 2 diabetes mellitus
PurposeType 2 diabetes mellitus (T2DM) lead to impaired cerebral blood perfusion, which leads to changes in brain function and affects the cognitive...
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Stacked LSTM based deep recurrent neural network with kalman smoothing for blood glucose prediction
BackgroundBlood glucose (BG) management is crucial for type-1 diabetes patients resulting in the necessity of reliable artificial pancreas or insulin...
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Analysis of Changes in Glucose and Lipid Metabolism in Patients with Clinically Severe Obesity and Type 2 Diabetes Mellitus Undergoing Laparoscopic Sleeve Gastrectomy—Prospective Observational Study
IntroductionWe still lack studies providing analysis of changes in glucose and lipid metabolism after laparoscopic sleeve gastrectomy (LSG) in...
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Differences in glycemic trends due to reconstruction methods after proximal gastrectomy from the perspective of continuous glucose-monitoring
PurposeIn recent years, clinicians have focused on the importance of preventing hypoglycemia. We evaluated the impact of different reconstruction...
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Assessing the temporal within-day glycemic variability during hospitalization in patients with type 2 diabetes patients using continuous glucose monitoring: a retrospective observational study
AimsFrequent and extensive within-day glycemic variability (GV) in blood glucose levels may increase the risk of hypoglycemia and long-term mortality...
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Glucose variability: a new risk factor for cardiovascular disease
Aims and data synthesisGlucose variability (GV) is increasingly considered an additional index of glycemic control. Growing evidence indicates that...