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Pediatric liver cirrhosis interventional procedures: from biopsy to transjugular intrahepatic portosystemic shunt
Cirrhosis is a complex diffuse process whereby the architecture of the liver is replaced by abnormal nodules because of the presence of fibrosis....
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Retrospective, single-center analysis of autoimmune hepatitis in Jordanian children: clinical features, treatments, and outcomes
ObjectivesThis study describes clinical, biochemical, and histological features and long-term outcomes in pediatric patients diagnosed with...
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Long-term outcomes and health-related quality of life 20 years after pediatric liver transplantation
Pediatric liver transplantation is a challenging surgical procedure requiring complex post-transplant patient management. Liver transplantation in...
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Systemic Complications Secondary to Chronic Liver Disease
The systemic sequelae of chronic liver disease (CLD) may be due to portal hypertension and shunting, malnutrition, and/or a low grade inflammatory...
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Prognostic markers in hepatitis A–related pediatric acute liver failure and validation of the Peds-hepatitis A virus prognostic model
ObjectivesHepatitis A virus (HAV) is the commonest cause for pediatric acute liver failure (PALF) in India. The objective of the study was to...
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An Approach to Investigations of Chronic Liver Disease
Chronic liver disease (CLD) in children is more diverse compared to adults with respect to the etiology, progression and response to therapy. After...
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LncOb rs10487505 variant is associated with leptin levels in pediatric non-alcoholic fatty liver disease
BackgroundLow and high leptin levels are associated with non-alcoholic fatty liver disease (NAFLD). The LncOb rs10487505 variant has been associated...
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Ascites and Chronic Liver Disease in Children
Development of ascites in children with chronic liver disease is the most common form of decompensation. It is associated with a poor prognosis and...
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Hypogonadism and nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD), recently proposed to be renamed to metabolic dysfunction-associated steatotic liver disease (MASLD), is a...
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Major complications after percutaneous biopsy of native or transplanted liver in pediatric patients: a nationwide inpatient database study in Japan
AimAlthough major complication rates following percutaneous liver biopsy (PLB) have been reported to be higher in children than in adults, scarce...
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Prognostic factors and scoring systems associated with outcome in pediatric acute liver failure
BackgroundPediatric acute liver failure (PALF) is an uncommon, devastating illness with significant mortality. Liver transplantation remains the...
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Magnetic resonance elastography in evaluation of liver fibrosis in children with chronic liver disease
BackgroundMagnetic resonance elastography (MRE) has been used to stage liver fibrosis in adults. We aimed to assess the agreement between the Ishak...
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Diagnosis and Management of Pediatric Acute Liver Failure: ESPGHAN and NASPGHAN 2022
Guidelines for management of pediatric acute liver failure (PALF) were recently published by the North American Society for Pediatric...
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Frequency of hepatitis C virus infection in patients with pediatric inflammatory bowel disease: a cross-sectional study
BackgroundPatients with pediatric inflammatory bowel disease (PIBD) are believed to be at higher risk of hepatitis C virus (HCV) infection not only...
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Comparison of liver T1 relaxation times without and with iron correction in pediatric autoimmune liver disease
BackgroundMagnetic resonance imaging (MRI) T1 relaxometry (map**) has been reported as a quantitative biomarker of liver injury due to inflammation...
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Association between liver diffusion-weighted imaging apparent diffusion coefficient values and other measures of liver disease in pediatric autoimmune liver disease patients
BackgroundMultiple quantitative magnetic resonance imaging (MRI) methods have been described to noninvasively detect and characterize liver fibrosis,...
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Treatment Options in Pediatric Behçet’s Disease
Behçet’s disease is a rare and poorly understood vasculitis affecting blood vessels of all types and sizes. Uveitis and oral and genital ulcers...
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Navigating the microbial maze: unraveling the connection between gut microbiome and pediatric kidney and urinary tract disease
The gut microbiome is made up of trillions of bacteria, viruses, archaea, and microbes that play a significant role in the maintenance of normal...
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Multicenter registry of pediatric inflammatory bowel disease from a develo** country
BackgroundDespite the rising incidence of pediatric inflammatory bowel disease (PIBD) globally, multicenter collaborative studies of PIBD children...
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Heart rate variability is associated with encephalopathy and outcomes in pediatric acute liver failure
BackgroundMore than half of children with pediatric acute liver failure (PALF) experience hepatic encephalopathy (HE), which is related to poor...