Search
Search Results
-
Utilization of Screening Breast MRI in Women with Extremely Dense Breasts
Purpose of reviewTo review the current evidence for the use of magnetic resonance imaging (MRI) as a supplemental breast cancer screening method for...
-
Integrated structure model-based virtual screening approaches identified anti-cancer agents against prostate cancer by targeting MAOB protein
BackgroundFlavin monoamine oxidase gene encodes a protein (MAOB) that forms a part of the flavin monoamine oxidase family in the outer membrane of...
-
Phytochemical screening, gas chromatograph/mass spectrometer (GCMS) analysis and molecular toxicological potential of Hunteria umbellata aqueous fruit extract against Staphylococcus aureus in accessory gene regulators (AGRs)
BackgroundFruits of Hunteria umbellata (HU) have been utilized in folk medicine as potent against Staphylococcus aureus (SA) infections,...
-
The early impacts of primary HPV cervical screening implementation in Australia on the pathology sector: a qualitative study
BackgroundThe transition of Australia’s National Cervical Screening Program from cytology to a molecular test for human papillomavirus (HPV) (locally...
-
Breast Cancer Screening in the Geriatric Population: Challenges and Future Considerations
Purpose of ReviewWith the aging population of the USA, the role of mammographic screening over the age of 75 is controversial. This review...
-
Experience of Antenatal Thalassemia Screening and Prenatal Diagnosis from a Tertiary Care Teaching Hospital in Punjab
Prevention of birth of thalassemia major children by identification of risk couples and prenatal diagnosis has been recommended as a realistic and...
-
-
Lipoprotein(a): a Case for Universal Screening in Youth
Purpose of ReviewLipoprotein(a) has emerged as a strong independent risk factor for cardiovascular disease. Targeted screening recommendations for...
-
Optimizing congenital cytomegalovirus detection by pool testing in saliva by a rapid molecular test
Universal congenital cytomegalovirus (cCMV) screening in saliva is increasingly recommended. The aim of our study was to correlate the performance of...
-
Post-mortem genetic testing in sudden cardiac death and genetic screening of relatives at risk: lessons learned from a Czech pilot multidisciplinary study
Sudden cardiac death (SCD) might have an inherited cardiac condition background. Genetic testing supports post-mortem diagnosis and screening of...
-
Induced pluripotent stem cells (iPSCs): molecular mechanisms of induction and applications
The induced pluripotent stem cell (iPSC) technology has transformed in vitro research and holds great promise to advance regenerative medicine. iPSCs...
-
CRISPR screening in hematology research: from bulk to single-cell level
The CRISPR genome editing technology has revolutionized the way gene function is studied. Genome editing can be achieved in single genes or for...
-
Establishment of a large-scale patient-derived high-risk colorectal adenoma organoid biobank for high-throughput and high-content drug screening
BackgroundColorectal adenoma (CA), especially high-risk CA (HRCA), is a precancerous lesion with high prevalence and recurrence rate and accounts for...
-
Diagnostic capabilities of artificial intelligence as an additional reader in a breast cancer screening program
ObjectivesWe aimed to evaluate the early-detection capabilities of AI in a screening program over its duration, with a specific focus on the...
-
Following the High-Risk Patient: Breast Cancer Risk-Based Screening
Breast cancer (BC) is the most common cancer occurring in women in the USA today, and accounts for more than 40,000 deaths annually (Giaquinto in CA...
-
The value of GLI1 and p16 immunohistochemistry in the premolecular screening for GLI1-altered mesenchymal neoplasms
Mesenchymal neoplasms with GLI1 alterations have recently been reported in several anatomic locations. Their morphology and immunohistochemistry...
-
Next-generation sequencing based newborn screening and comparative analysis with MS/MS
BackgroundNewborn screening (NBS), such as tandem mass spectrometry (MS/MS), may yield false positive/negative results. Next-generation sequencing...
-
Lung Cancer in Never Smokers: Delving into Epidemiology, Genomic and Immune Landscape, Prognosis, Treatment, and Screening
Lung cancer in never smokers (LCINS) represents a growing and distinct entity within the broader landscape of lung malignancies. This review provides...
-
Virtual screening reveals aprepitant to be a potent inhibitor of neutral sphingomyelinase 2: implications in blockade of exosome release in cancer therapy
PurposeExosomes are membrane-derived nano-vesicles upregulated in pathological conditions like cancer. Therefore, inhibiting their release is a...
-
Preoperative MRSA screening using a simple questionnaire prior elective total joint replacement
IntroductionThe purpose of this study was to evaluate the management and results of our standarized protocol for preoperative identification of MRSA...
