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Treatment of pulmonary arterial hypertension in patients with connective tissue diseases: a systematic review and meta-analysis
The evidence for the treatment of connective tissue disease-associated pulmonary arterial hypertension (CTD-PAH) mostly depends on subgroup or post...
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The citrullinated/native index of autoantibodies against hnRNP-DL predicts an individual “window of treatment success” in RA patients
BackgroundThere is a need for biomarker to identify patients “at risk” for rheumatoid arthritis (risk-RA) and to better predict the therapeutic...
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Nailfold videocapillaroscopic changes in patients with pulmonary arterial hypertension associated with connective tissue diseases
Pulmonary arterial hypertension (PAH) represents one of the most devastating complications in connective tissue diseases (CTDs). The aim of this...
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Clinical Significance of Antinucleolar Antibodies: Biomarkers for Autoimmune Diseases, Malignancies, and others
Nucleolar staining is one of the standard patterns in immunofluorescence antinuclear antibodies (ANA), seen in 5–9% of ANA in various conditions....
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Effect of preoperative long-term use of corticosteroids on the development of post-transplant lymphoproliferative disorders after lung transplantation: a single-center experience in Japan
PurposePost-transplant lymphoproliferative disorder (PTLD) is a major complication of lung transplantation (LTx). However, few studies on PTLD in...
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Serum uric acid is associated with disease severity and may predict clinical outcome in patients of pulmonary arterial hypertension secondary to connective tissue disease in Chinese: a single-center retrospective study
BackgroundPrevious studies have shown that serum uric acid (UA) levels are correlated with the severity of idiopathic pulmonary arterial hypertension...
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Case report: “an unexpected origin of coma in a young adult”
We report a peculiar case of acute non-traumatic coma due to neuromuscular hypoventilation syndrome caused by a non-traumatic spinal cord injury...
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A systematic review of the incidence, risk factors and prognosis of acute exacerbation of systemic autoimmune disease-associated interstitial lung disease
IntroductionAcute exacerbation (AE) is a devastating phenomenon and reported to be complicated with systemic autoimmune disease-associated...
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Use of machine learning models to predict prognosis of combined pulmonary fibrosis and emphysema in a Chinese population
BackgroundCombined pulmonary fibrosis and emphysema (CPFE) is a novel clinical entity with a poor prognosis. This study aimed to develop a clinical...
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Diagnostic accuracy and predictive value of autoantibody profiles in patients with systemic sclerosis: a single-center study
ObjectiveTo determine diagnostic accuracy and evaluate the predictive value of autoantibody profiles in patients with systemic sclerosis (SSc).
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Lungenmanifestationen bei adulten rheumatischen Erkrankungen
BackgroundRheumatic diseases frequently present with pulmonary involvement. All anatomic structures of the lungs can be affected. Interstitial lung...
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Connective Tissue Disease-Related Interstitial Lung Disease: Prevalence, Patterns, Predictors, Prognosis, and Treatment
Interstitial lung disease is a common pulmonary manifestation of connective tissue diseases and results in significant morbidity and mortality....
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An explainable machine learning-based model to predict intensive care unit admission among patients with community-acquired pneumonia and connective tissue disease
BackgroundThere is no individualized prediction model for intensive care unit (ICU) admission on patients with community-acquired pneumonia (CAP) and...
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Anti-Ro52 positivity is associated with progressive interstitial lung disease in systemic sclerosis—an exploratory study
BackgroundInterstitial lung disease (ILD) is the most common cause of death in patients with systemic sclerosis (SSc). Prognostic biomarkers are...
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Clinical features and risk factors of Raynaud’s phenomenon in primary Sjögren’s syndrome
ObjectiveThe aim at the current study was to investigate the clinical characteristics and risk factors of Raynaud’s phenomenon (RP) in patients with...
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A Narrative Review of Pathogenetic and Histopathologic Aspects, Epidemiology, Classification Systems, and Disease Outcome Measures in Systemic Sclerosis
Systemic sclerosis (SSc) is a rare systemic autoimmune disease, characterized by the presence of three main actors: vasculopathy, immune activation,...
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French recommendations for the management of systemic sclerosis
Systemic sclerosis (SSc) is a generalized disease of the connective tissue, arterioles, and microvessels, characterized by the appearance of fibrosis...
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Right atrial function for the prediction of prognosis in connective tissue disease-associated pulmonary arterial hypertension: a study with two-dimensional speckle tracking
Pulmonary arterial hypertension (PAH) is a serious and often fatal complication of connective tissue disease (CTD). Right atrial (RA) function is...
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IgG anti-hinge antibodies against IgG4 F(ab’)2 fragments generated using pepsin are useful diagnostic markers for rheumatoid arthritis: implications of the possible roles of metalloproteinases and IgG subclasses in generating immunogenic hinge epitopes
BackgroundPepsin agglutinators, discovered over 50 years ago, have been recently referred to as anti-hinge antibodies (AHAs) because of their...
