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Prevalence, correlates and in-hospital outcomes of kidney dysfunction in hospitalized patients with heart failure in Buea-Cameroon
BackgroundKidney dysfunction is common in patients with heart failure (HF) and has been associated with poor outcomes. This study aimed to determine...
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Association of metabolic dysfunction-associated fatty liver disease with kidney disease
Non-alcoholic fatty liver disease (NAFLD) is characterized by the accumulation of fat in more than 5% of hepatocytes in the absence of excessive...
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Kidney and urological involvement in Down syndrome: frequent, underestimated, but associated with impaired quality of life and risk of kidney failure
Patients with Down syndrome (DS) are at risk of multiorgan dysfunction; kidney and urological impairment are common. This is due to a likely...
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Nephron index rather than serum FGF 23 predicts endothelial dysfunction in early but not advanced chronic kidney disease patients
BackgroundEndothelial dysfunction is the primary step for the development of CKD-related cardiovascular disease. Early prediction and management can...
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A kidney-brain neural circuit drives progressive kidney damage and heart failure
Chronic kidney disease (CKD) and heart failure (HF) are highly prevalent, aggravate each other, and account for substantial mortality. However, the...
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Circulating osteoprotegerin as a cardiac biomarker for left ventricular diastolic dysfunction in patients with pre-dialysis chronic kidney disease: the KNOW-CKD study
BackgroundHeart failure with preserved ejection fraction (HFpEF) is a major cause of mortality in patients with chronic kidney disease (CKD), and...
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Adult Renal Dysfunction and Risk of Dementia or Cognitive Decline: Brain-Kidney Axis Hypothesis Based on a Systematic Review and Meta-Analysis
ObjectiveThe brain-kidney axis was proposed to emphasize roles of kidney functioning in modulating neurodegeneration. We aimed to evaluate the...
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Sunitinib-related high-grade proteinuria and allograft dysfunction in a kidney recipient: a rare case report
BackgroundSunitinib-induced high-grade proteinuria and irreversible renal allograft dysfunction are rare conditions. Here, we present a patient who...
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Global, regional, and national burden of kidney dysfunction from 1990 to 2019: a systematic analysis from the global burden of disease study 2019
ObjectiveWe aim to explore the prevalence and temporal trends of the burden of kidney dysfunction (KD) in global, regional and national level, since...
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Prognostic and predictive value of endothelial dysfunction biomarkers in sepsis-associated acute kidney injury: risk-stratified analysis from a prospective observational cohort of pediatric septic shock
BackgroundSepsis-associated acute kidney injury (SA-AKI) is associated with high morbidity, with no current therapies available beyond continuous...
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Subclinical cardiac dysfunction in pediatric kidney transplant recipients identified by speckle-tracking echocardiography
BackgroundKidney transplantation (KTx) improves prognosis in children with kidney failure; still, these patients are prone to cardiovascular damage...
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Urine alpha 1-microglobulin-to-creatinine ratio and beta 2-microglobulin-to-creatinine ratio for detecting CAKUT with kidney dysfunction in children
BackgroundThe leading cause of advanced chronic kidney disease (CKD) in children is congenital anomalies of the kidney and urinary tract (CAKUT)....
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Kidney transplant outcomes in children with simultaneous versus sequential heart–kidney transplants
BackgroundHeart transplant recipients frequently require kidney transplantation for concomitant advanced chronic kidney disease. Data on simultaneous...
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Association Between Kidney Dysfunction Types and Mortality Among Hospitalized Patients with Cirrhosis
Background and AimsKidney dysfunction is associated with increased mortality among patients with cirrhosis. We investigated whether kidney...
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Evolutions in Combined Heart-Kidney Transplant
Purpose of ReviewThis review describes management practices, outcomes, and allocation policies in candidates for simultaneous heart-kidney...
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Kidney disease and thyroid dysfunction: the chicken or egg problem
Patients with non-dialysis-dependant chronic kidney disease (NDD-CKD) and dialysis-dependant chronic kidney disease (DD-CKD) frequently also suffer...
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Moving toward a contemporary classification of drug-induced kidney disease
Drug-induced kidney disease (DIKD) accounts for about one-fourth of all cases of acute kidney injury (AKI) in hospitalized patients, especially in...
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Intermediate monocytes expansion and homing markers expression in COVID-19 patients associate with kidney dysfunction
Patients with severe SARS-CoV-2 infection have an overwhelming inflammatory response characterized by remarkable organs monocyte infiltration. We...
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Nontraditional risk factors in chronic kidney disease: correlation between creatinine clearance, Framingham risk score, endothelial dysfunction, and inflammation
BackgroundChronic kidney disease became a public health problem increasing healthcare burden. Our aim was to detect the relationship between...