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Synchronous bilateral primary ovarian cancer with right endometroid carcinoma and left high-grade serous carcinoma: a case report and literature review
BackgroundEpithelial ovarian cancer is the most frequent gynecologic malignancy; it has a poor prognosis and often occurs bilaterally. Most cases of...
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Development of a dual energy CT based model to assess response to treatment in patients with high grade serous ovarian cancer: a pilot cohort study
BackgroundIn patients with cancer, the current gold standard for assessing response to treatment involves measuring cancer lesions on computed...
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A bioinformatic analysis of WFDC2 (HE4) expression in high grade serous ovarian cancer reveals tumor-specific changes in metabolic and extracellular matrix gene expression
Human epididymis protein-4 (HE4/ WFDC2 ) has been well-studied as an ovarian cancer clinical biomarker. To improve our understanding of its functional...
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USP13 promotes development and metastasis of high-grade serous ovarian carcinoma in a novel mouse model
Epithelial ovarian cancer is the most lethal gynecologic malignancy and one of the most common causes of cancer mortality among women worldwide....
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Preoperative prediction of miliary changes in the small bowel mesentery in advanced high-grade serous ovarian cancer using MRI radiomics nomogram
PurposeTo develop and validate an MRI-based radiomics nomogram for the preoperative prediction of miliary changes in the small bowel mesentery...
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Identification of antigenic epitopes recognized by tumor infiltrating lymphocytes in high grade serous ovarian cancer by multi-omics profiling of the auto-antigen repertoire
Immunotherapeutic strategies aimed at enhancing tumor cell killing by tumor-specific T cells hold great potential for reducing tumor burden and...
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AMIGO2 is involved in the spread of peritoneal metastasis in serous ovarian cancer via promoting adhesion to the peritoneal mesothelial cells
BackgroundAmphoterin-induced gene and open reading frame 2 (AMIGO2) have been reported to be related to the prognosis of colorectal, gastric, and...
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Biological and prognostic value of ETV5 in high-grade serous ovarian cancer
BackgroundETS transcription factors are known to act as either positive or negative regulators of the expression of genes involved in various...
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Development and validation of an individualized gene expression-based signature to predict overall survival of patients with high-grade serous ovarian carcinoma
BackgroundHigh-grade serious ovarian carcinoma (HGSOC) is a subtype of ovarian cancer with a different prognosis attributable to genetic...
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Prediction of platinum resistance for advanced high-grade serous ovarian carcinoma using MRI-based radiomics nomogram
ObjectiveThis study aimed to explore the value of a radiomics nomogram to identify platinum resistance and predict the progression-free survival...
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Intra- and peritumoral radiomics for predicting early recurrence in patients with high-grade serous ovarian cancer
PurposeTo explore values of intra- and peritumoral CT-based radiomics for predicting recurrence in high-grade serous ovarian cancer (HGSOC) patients.
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Prognostic value of regulatory T cells and T helper 17 cells in high grade serous ovarian carcinoma
PurposeIn recent years the tumor microenvironment and its interaction with the tumor has emerged into research focus with increased attention to the...
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Discordance of PD-L1 expression in primary and metastatic ovarian high-grade serous carcinoma and its correlation with CD8 + tumor-infiltrating lymphocytes and patient prognosis
Differential expression of programmed death-1 ligand (PD-L1) and its clinical significance in primary and metastatic ovarian high-grade serous...
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Rett Syndrome with Synchronous Serous Ovarian Borderline Tumor and Recurrent Villous Adenomas of Colon
IntroductionRett syndrome is a rare neurodevelopmental disorder that is characterized by an early normal growth pattern followed by a progressive...
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Targeted Therapies in Low-Grade Serous Ovarian Cancers
Low grade serous carcinoma of the ovary has been delineated as a separate entity from its counterpart high grade serous carcinoma of the ovary....
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Proteomic analysis of exosomes secreted during the epithelial-mesenchymal transition and potential biomarkers of mesenchymal high-grade serous ovarian carcinoma
BackgroundThe epithelial-mesenchymal transition (EMT) promotes cell signaling and morphology alterations, contributing to cancer progression....
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Metastasis of serous ovarian carcinoma to the breast: a case report and review of the literature
BackgroundBreast metastasis from primary ovarian cancer is rare, with an estimated frequency of 0.07%. More than 110 cases are reported in the...
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Molecular cluster mining of high-grade serous ovarian cancer via multi-omics data analysis aids precise medicine
PurposeHGSOC is a kind of gynecological cancer with high mortality and strong heterogeneity. The study used multi-omics and multiple algorithms to...
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An immune related signature inhibits the occurrence and development of serous ovarian cancer by affecting the abundance of dendritic cells
Serous ovarian cancer is one of the major causes of cancer related death among women worldwide. The advanced diagnosis worsens the prognosis of...
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Natural Killer Cells: the Missing Link in Effective Treatment for High-Grade Serous Ovarian Carcinoma
Ovarian cancer (OC), especially high-grade serous cancer (HGSC), is a highly heterogeneous malignancy with limited options for curative treatment and...
