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1. A tree-based explainable AI model for early detection of Covid-19 using physiological data

   With the outbreak of COVID-19 in 2020, countries worldwide faced significant concerns and challenges. Various studies have emerged utilizing...

   Manar Abu Talib, Yaman Afadar, ... Ahmad Hasasneh in BMC Medical Informatics and Decision Making

   Article Open access 24 June 2024
   

2. SNAP25 is a potential target for early stage Alzheimer’s disease and Parkinson’s disease

   Background

   Alzheimer’s disease (AD) and Parkinson’s disease (PD), two common irreversible neurodegenerative diseases, share similar early stage...

   Qian Wang, Sijue Tao, ... Yingwei Zheng in European Journal of Medical Research

   Article Open access 06 December 2023
   

3. Identification of Early Warning Signals of Infectious Diseases in Hospitals by Integrating Clinical Treatment and Disease Prevention

   The global incidence of infectious diseases has increased in recent years, posing a significant threat to human health. Hospitals typically serve as...

   Lei Zhang, Min-ye Li, ... Hui Ma in Current Medical Science

   Article 18 April 2024

4. Development of a blood-based extracellular vesicle classifier for detection of early-stage pancreatic ductal adenocarcinoma

   Background

   Pancreatic ductal adenocarcinoma (PDAC) has an overall 5-year survival rate of just 12.5% and thus is among the leading causes of cancer...

   Juan Pablo Hinestrosa, Rosalie C. Sears, ... Paul R. Billings in Communications Medicine

   Article Open access 19 October 2023
   

5. Holistic Approach for the Early Detection of Oral Cancer: A Comprehensive Training Module

   Objectives

   Oral cancer is significantly high in India, and screening is an effective approach to downstage the disease. Educating Community Health...

   Keerthi Gurushanth, Sumsum P. Sunny, ... Praveen N. Birur in Journal of Maxillofacial and Oral Surgery

   Article 18 May 2024

6. Clinical value of noninvasive lens advanced glycation end product detection in early screening and severity evaluation of patients with diabetic kidney disease

   Background

   Advanced glycation end products (AGEs) deposited in the lens are correlated with those in the kidneys, indicating a possible value in...

   **aodi Zheng, Yuan Gao, ... Bingbing Zha in BMC Nephrology

   Article Open access 19 December 2023
   

7. Recent diagnostic techniques for the detection of Alzheimer’s disease: a short review

   Alzheimer’s disease (AD) is a neurological condition that affects millions of individuals around the world and for which there are few effective...

   Santosh S. Bhujbal, Minal M Kad, Vinita C. Patole in Irish Journal of Medical Science (1971 -)

   Article 16 December 2022
   

8. Testicular self-examination for early detection of testicular cancer

   Testicular cancer (TCa) commonly presents as a painless scrotal mass. It has been suggested that testicular self-examination (TSE) can help in early...

   Ryan I. H. Chong, Jeffrey J. Leow, ... Yew-Lam Chong in World Journal of Urology

   Article 10 April 2023

9. Early adverse physiological event detection using commercial wearables: challenges and opportunities

   Data from commercial off-the-shelf (COTS) wearables leveraged with machine learning algorithms provide an unprecedented potential for the early...

   Jesse Phipps, Bryant Passage, ... Roozbeh Jafari in npj Digital Medicine

   Article Open access 23 May 2024
   

10. Screening for early rheumatoid arthritis using high-frequency ultrasound, serum RANKL, and OPG detection

    Objective

    To conduct a comparative study of high-frequency ultrasound and magnetic resonance imaging (MRI) combined with serum RANKL and OPG...

    Hong Mo, Zhi-Hua Su, ... Feng-**a Li in Clinical Rheumatology

    Article 05 December 2023
    

11. Clinicopathological and molecular predictors of [¹⁸F]FDG-PET disease detection in HER2-positive early breast cancer: RESPONSE, a substudy of the randomized PHERGain trial

    Background

    The PHERGain study (NCT03161353) is assessing early metabolic responses to neoadjuvant treatment with trastuzumab-pertuzumab and...

    Antonio Llombart-Cussac, Aleix Prat, ... Geraldine Gebhart in European Journal of Nuclear Medicine and Molecular Imaging

    Article Open access 08 April 2024
    

12. Metabolite changes in the posterior cingulate cortex could be a signature for early detection of Alzheimer’s disease: a systematic review and meta-analysis study based on ¹H-NMR

    Background

    Posterior cingulate cortex (PCC) is a paralimbic cortical structure with a fundamental role in integrative functions of the default mode...

    Fakher Rahim, Mohammad Khalafi, ... Kiarash Shirbandi in The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

    Article Open access 05 May 2023
    

13. Validation, Deployment, and Real-World Implementation of a Modular Toolbox for Alzheimer’s Disease Detection and Dementia Risk Reduction: The AD-RIDDLE Project

    The Real-World Implementation, Deployment, and Validation of Early Detection Tools and Lifestyle Enhancement (AD-RIDDLE) project, recently launched...

    K. Malzbender, P. Barbarino, ... Miia Kivipelto in The Journal of Prevention of Alzheimer's Disease

    Article Open access 30 January 2024
    

14. High frequency of MEFV disease-causing variants in children with very-early-onset inflammatory bowel disease

    Background

    Biological similarities between inflammatory bowel disease (IBD) and familial Mediterranean fever (FMF) have been described in humans and...

    Aasem Abu Shtaya, Naama Orenstein, ... Lina Basel-Salmon in Pediatric Research

    Article 11 May 2024

15. Use of Circulating Tumor DNA (ctDNA) for Early Molecular Detection of Breast Cancer Relapse in Patients with Triple-Negative Breast Cancer (TNBC)

    Purpose of Review

    The intent of this review is to discuss the clinical utility of circulating tumor DNA (ctDNA) analysis for molecular residual...

    Nusayba A. Bagegni, Foluso O. Ademuyiwa in Current Breast Cancer Reports

    Article 21 September 2023

16. Early detection of peripheral neuropathy in patients with diabetes mellitus type 2

    Background

    Early diagnosis of diabetic polyneuropathy (DPN) can significantly improve the prognosis and help prevent severe complications. The aim of...

    Ahmed W. Fadel, Amin E. Nawar, ... Osama A. Ragab in The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

    Article Open access 10 January 2024
    

17. Development of a Serum-Based MicroRNA Signature for Early Detection of Pancreatic Cancer: A Multicenter Cohort Study

    Background

    A grim prognosis of pancreatic cancer (PCa) was attributed to the difficulty in early diagnosis of the disease.

    Aims

    Identifying novel...

    **g Huang, Ge Gao, ... Gary Guishan **ao in Digestive Diseases and Sciences

    Article Open access 07 March 2024
    

18. Early detection of cancer therapy cardiotoxicity by radionuclide angiography: An update

    Cancer therapy-induced cardiotoxicity is an emerging clinical and healthcare issue. Myocardial dysfunction and heart failure are mostly responsible...

    Cinzia Valzania, Andrea Paccagnella, ... Nazzareno Galié in Journal of Nuclear Cardiology

    Article 28 February 2023
    

19. Constructing diagnostic signature of serum microRNAs using machine learning for early pan-cancer detection

    Background

    Cancer is a major public health concern and the second leading cause of death worldwide. Various studies have reported the use of serum...

    Yuyan Xu, Wei Liao, ... Mingxin Pan in Discover Oncology

    Article Open access 04 July 2024
    

20. Urinary orosomucoid and retinol binding protein levels as early diagnostic markers for diabetic kidney Disease

    Background

    Diabetic kidney disease (DKD) is the most common microvascular complication of diabetes, which has been a major cause of end-stage renal...

    Xue-hong Zhou, Shu-yan Liu, ... Bao-hua Hou in BMC Nephrology

    Article Open access 04 December 2023