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Streptococcus equi subspecies zooepidemicus – a case report of sudden death in a German sow farm
A farm in North-West Germany experienced a high morbidity and mortality in their sow herd. Sows showed fever, lethargy, oedema, mucosal discharge and...
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Large-Scale Serological Survey of Influenza A Virus in South Korean Wild Boar (Sus scrofa)
In this comprehensive large-scale study, conducted from 2015 to 2019, 7,209 wild boars across South Korea were sampled to assess their exposure to...
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Toward better control of classical swine fever in wild boars: susceptibility of boar-pig hybrids to a recent Japanese isolate and effectiveness of a bait vaccine
We analyzed the pathogenicity of a recent Japanese classical swine fever virus (CSFV) to wild boars via an experimental infection using boar-pig...
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Membrane fusion, potential threats, and natural antiviral drugs of pseudorabies virus
Pseudorabies virus (PrV) can infect several animals and causes severe economic losses in the swine industry. Recently, human encephalitis or...
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Major swine viral diseases: an Asian perspective after the African swine fever introduction
Asia is a major pig producer of the world, and at present, African swine fever virus (ASFV) continues to significantly impact the Asian pig industry....
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Management of encephalomyocarditis virus infection in Italian pig farms: a case report
BackgroundEncephalomyocarditis virus (EMCV) has been isolated from many animals, frequently as the cause of fatal myocarditis, but pigs are the most...
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Current and prospective control strategies of influenza A virus in swine
BackgroundInfluenza A Viruses (IAV) are endemic pathogens of significant concern in humans and multiple keystone livestock species. Widespread...
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Antiviral activity of ISG15 against classical swine fever virus replication in porcine alveolar macrophages via inhibition of autophagy by ISGylating BECN1
Interferons (IFNs) induce the expression of interferon-stimulated genes (ISGs) for defense against numerous viral infections, including classical...
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African swine fever vaccines: a promising work still in progress
AbstractAfrican swine fever (ASF), a disease of obligatory declaration to the World Organization for Animal Health (OIE), has contributed to poverty...
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Transcriptome analysis of PK-15 cells expressing CSFV NS4A
BackgroundClassical swine fever (CSF) is a severe disease of pigs that results in huge economic losses worldwide and is caused by classical swine...
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Swine acute diarrhea syndrome coronavirus Nsp1 suppresses IFN-λ1 production by degrading IRF1 via ubiquitin–proteasome pathway
Swine acute diarrhea syndrome coronavirus (SADS-CoV) is a novel porcine enteric coronavirus that causes acute watery diarrhea, vomiting, and...
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Pseudorabies virus hijacks the Rab6 protein to promote viral assembly and egress
Pseudorabies virus (PRV) is recognized as the aetiological agent responsible for Aujeszky’s disease, or pseudorabies, in swine populations. Rab6, a...
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Development of an accurate lateral flow immunoassay for PEDV detection in swine fecal samples with a filter pad design
Porcine epidemic diarrhea virus (PEDV), as the main causative pathogen of viral diarrhea in pigs, has been reported to result in high morbidity and...
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A neutralizing monoclonal antibody-based competitive ELISA for classical swine fever C-strain post–vaccination monitoring
BackgroundVirus neutralization test (VNT) is widely used for serological survey of classical swine fever (CSF) and efficacy evaluation of CSF...
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Development and evaluation of duplex TaqMan real-time PCR assay for detection and differentiation of wide-type and MGF505-2R gene-deleted African swine fever viruses
BackgroundAfrican swine fever (ASF) is the most important disease to the pigs and cause serious economic losses to the countries with large-scale...
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Vertical transmission of porcine circovirus-like virus P1 in BALB/c mice
BackgroundPorcine circovirus-like virus P1 is the animal virus with the smallest genome discovered so far, and it has become widely distributed in...
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Guanylate-binding protein 1 inhibits nuclear delivery of pseudorabies virus by disrupting structure of actin filaments
The alphaherpesvirus pseudorabies virus (PRV) is the causative agent of pseudorabies, responsible for severe economic losses to the swine industry...
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Design of live-attenuated animal vaccines based on pseudorabies virus platform
Pseudorabies virus (PRV) is a double-stranded DNA virus with a genome approximating 150 kb in size. PRV contains many non-essential genes that can be...
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Guidelines for oral fluid-based surveillance of viral pathogens in swine
Recent decades have seen both rapid growth and extensive consolidation in swine production. As a collateral effect, these changes have exacerbated...
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Visual detection of porcine epidemic diarrhea virus by recombinase polymerase amplification combined with lateral flow dipstrip
BackgroundPorcine epidemic diarrhea virus (PEDV) is one of the most important enteric viruses causing diarrhea in pigs. The establishment of a rapid...
